CAS: 744266-99-7; Methyl 3-(Methyl(Pentyl)Amino)Propanoate

相似化合物

625120-81-2 625120-81-2 1095591-21-1

上下游产品

N-methylpentylamine acrylic acid methyl ester N-methyl-N-pentylamine oxalate

N-甲基正戊胺,丙烯酸甲酯(ma)置于甲醇体系中,用 甲醇 作为反应溶剂,化学反应 8.0H,以to Obtain 188.6 G N-Methyl-N-Pentyl-β-Alanine Methyl Ester (96.1%)的收率获得产物3-(N-甲基正戊氨基)丙酸甲酯
参考文献:Method For Synthesizing Bisphosphonate
标题:Method For Synthesizing Bisphosphonate
摘要:本发明涉及一种新型的多步合成3-(n-甲基-N-戊基)氨基-1-羟基丙烷-1,1-二膦酸,单钠盐,单水合物,其化学式为

专利信息

专利号:US-8178712-B2
优先权日:2006-06-23
标 题:Process for the synthesis of Ibandronate sodium
发明人：RAO DHARAMARAJ RAMCHANDRA; KANKAN RAJENDRA NARAYANRAO; GHAGARE MARUTI GANPATI
权利人:RAO DHARAMARAJ RAMCHANDRA; KANKAN RAJENDRA NARAYANRAO; GHAGARE MARUTI GANPATI; CIPLA LTD
摘要:The present invention relates to an improved process for the synthesis of Ibandronate sodium of formula (I). The present invention also provides novel processes for the synthesis of 3-[N-(methylpentyl)amino]propionic acid (III).

专利号:WO-2008058722-A1
优先权日:2006-11-16
标 题:Reagent and use thereof for the production of bisphosphonates
发明人：LERSTRUP KNUD; PREIKSCHAT HERBERT FRITZ; FISCHER ERIK
权利人:SANDOZ AS; LERSTRUP KNUD; PREIKSCHAT HERBERT FRITZ; FISCHER ERIK
摘要:A new liquid reagent is disclosed in form of an ionic liquid containing phosphorous acid and a tertiary amine. The reagent can be used as a replacement of phosphorous acid, where the new reagent as a liquid reagent can be handled using usual equipment for handling liquids and the dosing of the reagent can therefore be controlled more precisely in industrial plants compared to phosphorous acid, which is a solid at ambient temperature. The new liquid reagent is particular suitable for the synthesis of bisphosphonates.

专利号:US-7214818-B2
优先权日:2004-10-29
标题 :Method for synthesizing bisphosphonate
发明人：BAETZ FRIEDRICH; JUNGHANS BERND
权利人:HOFFMANN LA ROCHE
摘要:The invention relates to a novel multi step synthesis of 3-(N-methyl-N-pentyl) amino-1-hydroxypropane-1,1-diphosphonic acid, monosodium salt, monohydrate, of the formula

专利号:WO-2008125483-A2
优先权日:2007-04-11
标 题 :Multi step synthesis of ibandronate

专利号:US-7662990-B2
优先权日:2007-04-11
标 题:Process for preparing ibandronate
发明人：JUNGHANS BERND
权利人:HOFFMANN LA ROCHE
摘要:The invention relates to a novel multi step synthesis of 3-(N-methyl-N-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid, monosodium salt, monohydrate, of the formula

专利号:EP-2038291-B1
优先权日:2006-06-23
标 题:Process for the synthesis of ibandronate sodium