CAS: 55721-65-8; Boc-D-Ile-Oh

相似化合物

55780-90-0 13139-16-7 138775-22-1

上下游产品

L-isoleucine tert-butoxycarbonyloxy-6-chloro-1H-benzotriazole1-tert-butoxycarbonyloxy-6-chloro-1H-benzotriazole tert-butyl alcoholtert-butyl alcohol tert-butyl dicarbonatedi-tert-butyl dicarbonateε-Z-Lys-°CH3)B°C-Ileu-(Nε-Z-Lys-°CH3) tert-(butoxycarbonyl)isoleucine succinimidyl ester N-tert-Butyloxycarbonyl-L-leucyl-L-phenylalanin-heptylester 2-{(R)-1-[(2S,3S)-2-((S)-2-tert-Butoxycarbonylamino-3-methyl-pentanoylamino)-3-hydroxy-butyrylamino]-2-phenyl-ethyl}-thiazole-4-carboxylic acid methyl ester

(2S,3R)-2-Hydroxy-3-Methyl-N-Phenylpent-4-Enamide置于palladium On Activated Charcoal 4-二甲氨基吡啶,Lithium Hydroxide,Sodium Azide,氢气,双氧水,三乙胺体系中,用 四氢呋喃,乙醇,二氯甲烷,水,N,N-二甲基甲酰胺,乙腈 作为反应溶剂,20.0~70.0 °C,101.33 Kpa 条件下,反应生成 Boc-D-异亮氨酸
参考文献:Asymmetric,Anti-Selective Scandium-Catalyzed Sakurai Additions To Glyoxyamide. Applications To The Syntheses Of N-Boc D-Alloisoleucine And D-Isoleucine
标题:Asymmetric,Anti-Selective Scandium-Catalyzed Sakurai Additions To Glyoxyamide. Applications To The Syntheses Of N-Boc D-Alloisoleucine And D-Isoleucine
摘要:An Enantio-And Diastereoselective Sakurai-Hosomi Reaction,Catalyzed By Chiral Scandium Pyridyl-Bis(Oxazoline) (Pybox) Complexes,Has Been Developed. Both Alkyl-And Aryl-Substituted Allylsilanes Are Effective Coupling Partners With N-Phenylglyoxamide. Applications Of This Reaction To The Asymmetric Syntheses Of N-Boc D-Alloisoleucine And D-Isoleucine Are Described.
DOI:10.1021/ol0604771