CAS: 511295-00-4; (2,3,4,6-Tetrafluorophenyl)Boronic Acid

该化合物是一种有机有机体化合物,其特征是,一种附于苯环的碳酸功能组,以四氟原子代替四氟原子,这种化合物一般具有高度的抗体,因为二氟酸酸混合物可参与各种化学反应,包括铃木结合和其他交叉反应,使其在有机合成和材料科学中具有价值.氟原子的存在会增强它的电子特性,有可能增加其脂质,并改变其相对于非氟模拟体的再活性.此外,氟基亚成分会影响化合物在不同溶剂中的溶解性和稳定性. 2,3,4,6-四氟苯乙基酸经常用于制药和农用化学物质以及复杂的有机分子合成中.在处理这一化合物时,应参考安全数据,因为溴酸对水分敏感,可能需要具体的储存条件.

英文名称(2,3,4,6-Tetrafluorophenyl)Boronic Acid
中文名称2,3,4,6-四氟苯硼酸
IUPAC名称(2,3,4,6-tetrafluorophenyl)boronic acid
其它别名2,3,4,6-TETRAFLUOROBENZENEBORONIC ACID; 2,3,4,6-TETRAFLUOROPHENYLBORONIC ACID
CAS编号511295-00-4
MFCD编号:MFCD04039309
EINECS号:676-443-4
分子式:C6H3BF4O2分子量:193.89
产品CID: 1500266
产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

相似结构搜索
InChIKey: FYJHKJSCYHAWFW-UHFFFAOYSA-N
InChI=1S/C6H3BF4O2/c8-2-1-3(9)5(10)6(11)4(2)7(12)13/h1,12-13H
计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数1.0

MSDS等安全信息

GHS符号GHS07
警示词Warning
危险描述H315-H319-H335
防范说明P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
危险品标志Xi
安全声明S26,S37
危险类别码R36/37/38
WGK Germany3

上下游产品

Trimethyl borate 1,2,3,5-tetrafluorobenzene 1,2,3,5-tetrafluorobenzene

合成工艺路线路线简述

📜在盐酸,水体系中,化学反应生成 (2,3,4,6-C6Hf4)2Boh,2,3,4,6-四氟苯硼酸
参考文献:Polyfluoroorganoboron-Oxygen Compounds. 7. Studies Of Conversion Of [(C6Hnf5-N)B(Ome)3]-Into [(C6Hnf5-N)2B(Ome)2]-(N = 0,1)
标题:Polyfluoroorganoboron-Oxygen Compounds. 7. Studies Of Conversion Of [(C6Hnf5-N)B(Ome)3]-Into [(C6Hnf5-N)2B(Ome)2]-(N = 0,1)
摘要:在二氯甲烷-Dme溶液中研究了盐li[(C6Hnf5-N)B(Ome)3] (N = 0,1) 转化为(Li.dme)[(C6Hnf5-N)2B(Ome)2].观测到的速率常数k从(21.4 +/-0.9) x 10-3升摩尔-1秒-1 (Li[c6F5B(Ome)3]) 下降到(6.99 +/-0.11) x 10-3升摩尔-1秒-1 (Li[(2,3,5,6-C6Hf4)B(Ome)3]),最终到(2.94 +/-0.05) x 10-3升摩尔-1秒-1 (Li[(2,3,4,6-C6Hf4)B(Ome)3]),而li[(2,3,4,5-C6Hf4)B(Ome)3] 不发生任何转化.对(Li.dme)[(C6Hnf5-N)2B(Ome)2]的水解导致相应的硼酸,而用含hf的水溶液处理它们,结果是高产率的m[(C6Hnf5-N)2Bf2] (M = Bu4N,K).
DOI:10.1135/cccc20081681

专利信息

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.