CAS: 348-28-7; 4-Fluoro-2-Hydroxybenzaldehyde

上下游产品

CAS号50-00-0 甲醛 | CAS号372-20-3 3-氟苯酚 | CAS号75-05-8 乙腈 | CAS号67-66-3 氯仿 | CAS号395-82-4 4-氟-2-甲氧基苯甲酸 | CAS号345-29-9 4-氟水杨酸 | CAS号450-83-9 4-氟-2-甲氧基苯甲醛 | CAS号399-00-8 5-溴-4-氟-2-羟基苯甲醛 | CAS号202857-89-4 2-(苄氧基)-4-氟苯甲醛 | CAS号312314-26-4 4-苄氧基-6-氟吲唑

3-氟苯酚,乌洛托品置于水,三氟乙酸体系中,化学反应 10.0H,以30%的收率获得产物4-氟-2-羟基苯甲醛
参考文献:取代基对亚稳态光酸的影响:其光化学性质的设计,合成和评估
标题:取代基对亚稳态光酸的影响:其光化学性质的设计,合成和评估
摘要:最近,亚稳态光酸已被广泛用于控制许多化学和生物过程以及可见光应用中的质子转移.通常,取代基对分子的光化学性质有很大的影响,这将进一步影响其应用.然而,取代基对亚稳态光酸的影响尚未得到系统的研究.在这项工作中,在具有大范围σ-π电子-给体-受体能力的取代基的基础上,设计和合成了16种亚稳态光酸衍生物.取代基对颜色显示的影响[或最大吸收带],溶解度,P K A值,暗/光酸度,光敏性和松弛动力学被详细研究.这项研究将有助于有前途的光酸的目标设计和合成,以及其光控质子释放过程在功能材料/器件中的应用.
DOI:10.1002/asia.201801687

专利信息

专利号:US-7026339-B2
优先权日:2003-11-07
标题 :Inhibitors of HCV NS5B polymerase
发明人：YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY
权利人:YANG FAN; ZHANG BO; WICNIENSKI NANCY ANNE; PFEFFERKORN JEFFREY ALLEN; GREENE MEREDITH L; CHEN KE; NUGENT RICHARD A; REDING MATTHEW TODD; KELLY ROBERT CHARLES; MITCHELL MARK A; FUNK LEE A; HEIER III RICHARD FREDERICK; ANDERSON REBECCA MERRY
摘要:The present invention relates to compounds, process for their synthesis, compositions and methods for the treatment and prevention of hepatitis C virus (HCV) infection. In particular, the present invention provides novel compounds, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment or prevention of HCV infection. The present invention also provides processes and intermediates for the synthesis of these compounds.

专利号:US-7189749-B2
优先权日:1999-06-25
标 题 :Substituted phenoxyacetic acids
发明人：VAN ZANDT MICHAEL C
权利人:INST FOR PHARM DISCOVERY INC
摘要:Disclosed are substituted phenoxyacetic acids useful in the treatment of chronic complications arising from diabetes mellitus. Also disclosed are pharmaceutical compositions containing the compounds, alone or in combination with other therapeutic agents, and methods of treatment employing the compounds and pharmaceutical compositions, as well as methods for their synthesis.

专利号:US-2023383342-A1
优先权日:2022-05-31
标 题 :Compositions and methods for nucleic acid sequencing
发明人：WU XIAOLIN; MCCAULEY PATRICK; DHARMARWARDANA MADUSHANI; NIRANTAR SAURABH; GOLYNSKIY MISHA; YANG XIANGYUAN; NEELAKANDAN RAMESH; MACKWORTH BENEDICT; ANASTASI CAROLE; KARUNAKARAN AATHAVAN; VESSERE GERY M; BRACHER DAVID
权利人:ILLUMINA CAMBRIDGE LTD; ILLUMINA SINGAPORE PTE LTD; ILLUMINA INC; ILLUMINA SOFTWARE INC
摘要:Embodiments of the present disclosure relate to kits, compositions, and methods for nucleic acid sequencing, for example, two-channel nucleic acid sequencing by synthesis using blue and green light excitation. In particular, unlabeled nucleotides for incorporation may be used in conjunction with affinity reagents containing detectable labels excitable by blue and/or green lights, for specific binding to each type of nucleotides incorporated.