CAS: 14431-43-7; (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2,3,4,5-Tetraol Hydrate

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专利信息

专利号:US-8754111-B2
优先权日:2011-01-26
标 题 :Method and substances for preparation of N-substituted pyridinium compounds
发明人：GEBAUER PETER; HEINDL DIETER; HORN CARINA
权利人:ROCHE DIAGNOSTICS OPERATIONS
摘要:A method for the synthesis of N-substituted 3-acylated pyridinium compounds by reacting a pentamethine precursor with a primary amine.

专利号:US-2024117398-A1
优先权日:2021-01-20
标 题:Production of oligosaccharides comprising ln3 as core structure in host cells
发明人：AESAERT SOFIE; BEAUPREZ JOERI; PETERS GERT; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:Described is a method of producing an oligosaccharide comprising a lacto-N-triose (LN3; GlcNAc-beta1,3-Gal-beta1,4-Glc) as a core trisaccharide by cultivation with a genetically modified cell, as well as the genetically modified cell used in the method. The genetically modified cell comprises at least one nucleic acid sequence coding for a galactoside beta-1,3-N-acetylglucosaminyltransferase and a glycosyltransferase involved in the synthesis of an oligosaccharide comprising LN3 as a core trisaccharide and at least one nucleic acid sequence expressing a membrane protein. Furthermore, the present invention provides for a purification of the oligosaccharide comprising LN3 as a core trisaccharide from the cultivation.

专利号:WO-2011147453-A1
优先权日:2010-05-26
标 题 :Enzymatic synthesis of nootkatone
发明人：ZORN HOLGER; FRAATZ MARCO ALEXANDER; RIEMER STEPHANIE JOHANNA LUISE; TAKENBERG MEIKE; KRINGS ULRICH; BERGER RALF GUENTER; MARX STEFAN; ZELENA KATERYNA
权利人:N ZYME BIOTEC GMBH; ZORN HOLGER; FRAATZ MARCO ALEXANDER; RIEMER STEPHANIE JOHANNA LUISE; TAKENBERG MEIKE; KRINGS ULRICH; BERGER RALF GUENTER; MARX STEFAN; ZELENA KATERYNA
摘要:The invention relates to oxygenases from Pleurotus sapidus for the biocatalytic oxidation of valencene to form nootkatone (terpenes).

专利号:US-2011054174-A1
优先权日:2009-08-28
标 题:Process for the preparation of a glucokinase activator compound
发明人：BACHMANN STEPHAN; FETTES ALEC; IDING HANS; WIRZ BEAT; ZUTTER ULRICH
权利人:BACHMANN STEPHAN; FETTES ALEC; IDING HANS; WIRZ BEAT; ZUTTER ULRICH
摘要:The present invention relates to a process for the preparation of a compound of formula I, n n n n n n n n n n wherein R 1 is C 1-6 -alkyl and R 2 is hydrogen or halogen. n (R)-2-phenyl propionic acid derivatives of formula I are key intermediates in the synthesis of 5-substituted-pyrazine or pyridine glucokinase activators of the formula Xa, n n n n n n n n n n which have the potential to be useful for the treatment and/or prophylaxis of type II diabetes.

专利号:US-2024191270-A1
优先权日:2021-04-16
标 题 :Fermentative production
发明人：BEAUPREZ JOERI; COUSSEMENT PIETER; DECOENE THOMAS
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology and metabolic engineering. More particularly, the present invention is in the technical field of metabolically engineered cells and use of said cell in a cultivation, preferably a fermentation. The present invention describes a cell for the production of a compound. The cell comprises a pathway for the production of the compound, which can be a disaccharide, oligosaccharide and/or a Neu(n)Ac-containing bioproduct, wherein (n) is 4, 5, 7, 8 or 9 or a combination thereof. The cell is metabolically engineered for enhanced synthesis of acetyl-Coenzyme A. The invention also resides in a method of producing such compound by cultivation, preferably a fermentation, with such a cell.

专利号:US-2021317023-A1
优先权日:2016-04-14
标 题:Highly efficient aerobic phosphorus-removing bacteria capable of synthesizing nanoparticles by microbial self-assembly using waste water
发明人：ZHOU WEIZHI; JIANG LI; HUANG ZHAOSONG; WANG YANRU; ZHAO HAIXIA
权利人:UNIV SHANDONG
摘要:The present application discloses a class of aerobic efficient-phosphorus-removal bacteria that enable to biologically self-assemble and synthesize nanoparticles while wastewater treatment, including Shewanella sp. CF8-6, Psychrobacter aquimaris X3-1403, and Erythrobacter citreus X3-1411. The strains in the present application have a high adaptability, which may grow, remove nutrients including phosphorus and synthesize nanoparticles within a broad range of pH values, salinity, temperatures, and nutrition concentrations of wastewater. Particularly, the outstanding performance of phosphorous removal at high-salinity has a high significance in wastewater treatment from seawater utilization such as seawater toilet-flushing to solve the fresh water resource deficiency. Self-flocculation and self-assembly are the important properties of the strains to form biofilms and synthesize calcium phosphate nanoparticles at low-concentrations, while decomposing contaminants in the wastewater. The application provides an environmental-friendly nanoparticle synthesis method with low-cost and without chemical additives, which realizes the efficient treatment of wastewater and high value phosphorous resources recovery.