CAS: 105-45-3; Methyl 3-Oxobutanoate

相似化合物

590-90-9 53562-86-0 1487-49-6

上下游产品

CAS号674-82-8 双乙烯酮 | CAS号67-56-1 甲醇 | CAS号1694-31-1 乙酰乙酸叔丁酯 | CAS号623-43-8 巴豆酸甲酯 | CAS号1487-49-6 3-羟基丁酸甲酯 | CAS号79-20-9 乙酸甲酯 | CAS号77-92-9 柠檬酸 | CAS号2033-24-1 丙二酸环(亚)异丙酯 | CAS号75-36-5 乙酰氯 | CAS号201230-82-2 carbon monoxide | CAS号105702-03-2 1,4-diacetyl-3-... | CAS号100-02-7 对硝基苯酚 | CAS号689-67-8 6,10-二甲基-5,9-十一... | CAS号141-10-6 6,10-二甲基-3,5,9-... | CAS号134143-47-8 10-methyl-6-met... | CAS号105737-79-9 10-methyl-6-met... | CAS号104990-30-9 methyl 2-[(2,4-... | CAS号53779-37-6 (5E,8Z)-6,10-di... | CAS号105553-49-9 10-methyl-6-met... | CAS号100063-41-0 5-Methyl-2-phen...

5-(1-羟基乙亚基)-2,2-二甲基-1,3-二氧杂环己-4,6-二酮 以 乙醇 用作溶剂,化学反应 3.0H,反应生成乙酰乙酸甲酯
参考文献:在无金属催化剂,无外源氧化剂和无外源电解质的条件下电化学合成多功能氧化铵
标题:在无金属催化剂,无外源氧化剂和无外源电解质的条件下电化学合成多功能氧化铵
摘要:已经开发了2.5-取代的吡唑啉-5-酮与硫氰酸铵之间的电化学氧化交叉偶联反应,从而在金属催化剂,外源氧化剂和外源电解质-的作用下产生了一系列前所未有的交叉偶联产物.免费条件.值得注意的是,由于所得的交叉偶联产物几乎不溶于mecn,因此无需硅胶柱纯化即可提供纯产物.此外,制备的氧化铵是用于合成官能化吡唑衍生物的通用构建基.
Doi:10.1039/d1Cc00486G

专利信息

专利号:EP-0454867-B1
优先权日:1989-11-17
标题:A METHOD FOR THE SYNTHESIS OF $g(a), $g(b)-UNSATURATED KETONES
发明人：TSUKASHIMA KEIICHI TAKAOKA PLA; NAKAJIMA MASASHI TAKAOKA PLANT; FUJIMARU MASAYOSHI TAKAOKA PLA; SUZUKI KENJI TAKAOKA PLANT
权利人:NIPPON SODA CO
摘要:The present invention relates to a method for the synthesis of alpha , beta -unsaturated ketones which comprises, in the method for the synthesis of alpha , beta -unsaturated ketones represented by general formula (I) (where R<1> is an aliphatic group with a side chain at the 1 position, an alicyclic group, a substituted alicyclic group, a heterocyclic group, a substituted heterocyclic group, a phenyl group or a substituted phenyl group), reacting aldehydes represented by general formula (II): R<1>CHO (where R<1> is as defined above) with alkali metal salt of acetoacetic acid represented by general formula (III) (where M<+> is an alkali metal ion), in the presence as a catalyst of 3-azabicyclo[3,2,2] nonane, a cyclic secondary amine represented by general formula (1) (where n is 3 or more and up to 5, m is 1 or more and up to 10, R<2> is an alkyl group having 1 to 10 carbon atoms and of straight chain or with side chains, an alkyl group substituted by alicyclic groups or phenyl groups, an alicyclic group which may be substituted by lower alkyl groups, or a phenyl group which may be substituted by lower alkyl groups, and an R<2> substitution position is at a carbon atom other than the two adjacent to N), a cyclic secondary amine represented by general formula (2) (where l is 1 or more and up to 6, a ring with N is a 6-membered, 7-membered or 8-membered ring, the two neighbors of N are methylene, R<3> is a lower alkyl group, its substitution position is at a carbon atom other than the two adjacent to N, and (a) is an alicyclic group or a phenyl group), or a secondary amine represented by general formula (3): CH3NHCH2R<4> (where R<4> is an aliphatic group having 5 to 17 carbon atoms and of straight chain or with side chains, an alicyclic group which may be substituted by lower alkyl groups, a phenyl group which may be substituted by lower alkyl groups, or an alkyl group substituted by phenyl groups), in a mixture solvent of water and water-insoluble organic solvent, while keeping the pH constant with mineral acid, and by adjusting the amount of water.

专利号:US-9199913-B2
优先权日:2011-04-25
标 题:Process for continous flow synthesis of beta-amino crotonate
发明人：KULKARNI ARVIND A; JOSHI ANNA R; JOSHI RAMESH R
权利人:KULKARNI ARVIND A; JOSHI ANNA R; JOSHI RAMESH R; COUNCIL SCIENT IND RES
摘要:Beta aminocrotonates are important intermediates for the synthesis of Ca channel blockers. The processes available in the art are batch processes with yields about 85%. There are no continuous processes available for the synthesis of such compounds. This gap in the art is addressed by the invention by disclosing a continuous process resulting in high yields of beta amino crotonates.

专利号:US-5484949-A
优先权日:1993-01-29
标题:Method for the synthesis of α β-unsaturated ketones
发明人：TSUKASHIMA KEIICHI; NAKAJIMA MASASHI; FUJIMARU MASAYOSHI; SUZUKI KENJI
权利人:NIPPON SODA CO
摘要:The present invention relates to a method for the synthesis of alpha , beta -unsaturated ketones which comprises, in the method for the synthesis of alpha , beta -unsaturated ketones represented by general formula reacting aldehydes represented by general formula R1CHO (where R1 is as defined above) with alkali metal salt of acetoacetic acid represented by general formula sence as a catalyst of 3-azabicyclo[3,2,2]nonane, a cyclic secondary amine represented by general formula (1) (1) a cyclic secondary amine represented by general formula (2) (2) (where, l is 1 or more and up to 6, a ring with N is a 6-membered, 7-membered or 8-membered ring, the two neighbors of N are methylene, R3 is a lower alkyl group, its substitution position is at a carbon atom other than two those adjacent to N, and is an alicyclic group or a phenol group), or a secondary amine represented by general formula (3) CH3NHCH2R4(3) in a mixuture solvent of water and water-insoluble organic solvent, while keeping the pH constant with mineral acid, and by adjusting an amount of water.

专利号:US-6642035-B2
优先权日:2001-01-26
标题 :Synthesis of B-keto esters
发明人：JANDA KIM D; CORDOVA ARMANDO
权利人:SCRIPPS RESEARCH INST
摘要:β-keto esters are prepared by way of a lipase-catalyzed transesterification. The synthetic methodology provides a simple scheme for the synthesis of optically active β-keto esters that are useful building blocks and starting materials for natural product synthesis. Moreover, the methodology employs mild, solvent-free conditions. The methodology may also be employed for resolving racemic alcohols.

专利号:US-6143887-A
优先权日:1998-05-14
标题:Process for the stereoselective synthesis of 16-substituted-4-aza-androstanones
发明人：GRATALE DOMINICK F; TOLMAN RICHARD L; SAHOO SOUMYA P
权利人:MERCK & CO INC
摘要:The novel process of the present invention involves the stereoselective synthesis of certain 16β-substituted 4-aza-5α-androstan-3-ones and the useful intermediates obtained therein.

专利号:WO-2022036662-A1
优先权日:2020-08-21
标题:Method for enzymatic synthesis of 3-hydroxybutyrate
发明人：FAN WENCHAO; GAO SHULIANG; WANG JINGANG; LIANG YAN; YANG HAIFENG; REN LIANG; Yuan shenglun
权利人:ZHEJIANG HUARUI BIOTECHNOLOGY CO LTD
摘要:Provided is a method for the enzymatic synthesis of 3-hydroxybutyrate. According to the method, acetoacetate is taken as a substrate, and a reduction reaction is catalyzed with an alcohol dehydrogenase of SEQ ID No:1 or a mutant thereof of SEQ ID Nos:3-27, to obtain 3-hydroxybutyrate.