CAS: 76578-14-8; Quizalofop-Ethyl

该化合物是一种选择性的抗生除草剂,主要用于控制宽叶麻作物中的草杂草,属于除草剂的丙氧苯丙基丙酰丙丙烯酯类别和功能,抑制对植物脂肪酸合成至关重要的酶乙酰丙酰氨基氨基乙基酶.这一机制会破坏细胞膜完整性,并最终造成植物死亡.基萨洛福乙基的特点是它对哺乳动物和鸟类的毒性相对较低,因此在农业应用中成为首选.它通常用于液体配方,并通过目标植物的叶子吸收.该化合物在对多种草种具有效力,同时对许多宽叶麻作物是安全的,并允许采用综合的除草管理战略.此外,它具有适度的环境持久性,需要谨慎管理,以尽量减少对非目标物种和生态系统的潜在影响.适当的应用技术和遵守所建议的准则对于最大限度地发挥其效力和尽量减少环境风险至关重要.

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76578-79-5 243455-09-6 338394-64-2

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6-chloro-2-(4-hydroxyphenoxy)quinoxaline ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate 2,6-dichloroquinoxaline ethanolquizalofop-p (RS)-tetrahydrofuran-2-ylmethyl (R)-2-[4-(6-chloro-2-quinoxalinyloxy)phenoxy]propionate

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    专利信息


    专利号:EP-1105359-B1
    优先权日:1998-08-21
    标 题:Solid phase synthesis of compounds by carbon-carbon bond forming mitsunobu reactions
    发明人:CHATURVEDI SURENDRAKUMAR
    权利人:PE CORP NY
    摘要:Processes are provided for the Mitsunobu alkylation reaction of carbon-carbon bond formation between a solid support reagent and a reagent in solution. The resulting novel products can be prepared as a combinatorial library by high-throughput, parallel synthesis under robotic automation. Cleaved or support-bound products are useful precursors to biologically active compounds.

    专利号:US-11919928-B2
    优先权日:2016-03-16
    标题 :Method for producing dihydrotentoxin
    发明人:KUBO TAKASHI; MACHIDA MASAYUKI; FUJIOKA TOMONORI; YAMAGUCHI Shigenari; KAWAI KIYOSHI
    权利人:KUMIAI CHEMICAL INDUSTRY CO
    摘要:An object of the present invention is to identify an enzyme having activity of synthesizing dihydrotentoxin that is a tentoxin precursor and an enzyme having activity of synthesizing tentoxin using dihydrotentoxin as a substrate. The present invention concerns a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 16 and having activity of nonribosomal peptide synthesis of dihydrotentoxin and a tentoxin synthesis-related gene encoding a protein comprising the amino acid sequence of SEQ ID NO: 18 and having activity of converting dihydrotentoxin to tentoxin.

    专利号:US-2021386068-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and very long chain fatty acid (vlcfa) synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a VLCFA synthesis inhibitor herbicide. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof, and (b) a VLCFA synthesis inhibitor herbicide.

    专利号:US-2021352899-A1
    优先权日:2018-11-07
    标题 :Compositions comprising pyridine carboxylate herbicides and fatty acid and lipid synthesis inhibitor herbicides
    发明人:KISTER JEREMY; SATCHIVI NORBERT M
    权利人:CORTEVA AGRISCIENCE LLC
    摘要:Disclosed herein are compositions comprising (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof. Also disclosed herein are methods of controlling undesirable vegetation, comprising applying to vegetation or an area adjacent the vegetation or applying in soil or water to control the emergence or growth of vegetation (a) a pyridine carboxylate herbicide or an agriculturally acceptable N-oxide, salt, or ester thereof and (b) a fatty acid and lipid synthesis inhibitor (FA/LSI) herbicide, an agriculturally acceptable salt or ester thereof, or mixtures thereof.

    专利号:US-9644469-B2
    优先权日:2012-07-24
    标题 :Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylic acid or a derivative thereof and VLCFA and lipid synthesis inhibiting herbicides
    发明人:YERKES CARLA N; MANN RICHARD K; SHIRAISHI IKUO; YANAGIYAMA SHINGO; SATCHIVI NORBERT M
    权利人:DOW AGROSCIENCES LLC
    摘要:A synergistic herbicidal composition containing (a) a compound of formula (I): n nor an agriculturally acceptable salt or ester thereof and (b) VLCFA and fatty acid/lipid synthesis inhibiting herbicides, including but not limited to, acetochlor, alachlor, anilofos, benfuresate, cafenstrole, dimethenamid-P, fentrazamide, indanofan, flufenacet, mefenacet, s-metolachlor, molinate, pethoxamid, pretilachlor, prosulfocarb, pyroxasulfone, thenylchlor and thiobencarb, or a salt or ester thereof, provide synergistic weed control of undesirable vegetation in direct-seeded, water-seeded and transplanted rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crops, vegetables, industrial vegetation management (IVM) or rights-of-way (ROW).

    专利号:US-2010190794-A1
    优先权日:2007-06-12
    标 题:Herbicidally Active Composition
    发明人:HUPE EIKE; MOBERG WILLIAM KARL; REINHARD ROBERT; SIEVERNICH BERND; KIBLER ELMAR
    权利人:BASF SE
    摘要:The present invention relates to herbicidally active compositions comprising at least one piperazinedione compound of the formula I n n n n n n n n n n n n in which: n R x , R y are each hydrogen or together are a chemical bond; n R 1 is cyano or nitro; n R 2 is hydrogen, fluorine, chlorine, C 1 -C 2 -alkyl, ethenyl or C 1 -C 2 -alkoxy; n R 3 is fluorine or hydrogen; n R 4 is methyl; n R 5 is hydrogen, methyl or ethyl; n R 6 is hydrogen, methyl or ethyl; and n R 7 is hydrogen or halogen; n and at least one further active compound selected from the group consisting of n b1) lipid biosynthesis inhibitors; n b2) acetolactate synthase inhibitors (ALS inhibitors); n b3) photosynthesis inhibitors; n b4) protoporphyrinogen-IX oxidase inhibitors, n b5) bleacher herbicides; n b6) enolpyruvyl shikimate 3-phosphate synthase inhibitors (EPSP inhibitors); n b7) glutamine synthetase inhibitors; n b8) 7,8-dihydropteroate synthase inhibitors (DHP inhibitors); n b9) mitose inhibitors; n b10) inhibitors of the synthesis of very long chain fatty acids (VLCFA inhibitors); n b11) cellulose biosynthesis inhibitors; n b12) decoupler herbicides; n b13) auxin herbicides; n b14) auxin transport inhibitors; n b15) other herbicides, and n C) safeners.

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    主要参考文献


    1: Zhang H, Li M, Li J, Wang G, Liu Y. Purification and properties of a novel quizalofop-p-ethyl-hydrolyzing esterase involved in quizalofop-p-ethyl degradation by Pseudomonas sp. J-2. Microb Cell Fact. 2017 May 10;16(1):80. doi: 10.1186/s12934-017-0695-8.
    2: Zhu LZ, Qi SZ, Cao FJ, Mu XY, Yang Y, Wang C. Quizalofop-P-ethyl exposure increases estrogen axis activity in male and slightly decreases estrogen axis activity in female zebrafish (Danio rerio). Aquat Toxicol. 2017 Feb;183:76-84. doi: 10.1016/j.aquatox.2016.12.011. Epub 2016 Dec 12. Epub 2016 Sep 13. doi: 10.1016/j.jchromb.2016.07.043. Epub 2016 Jul 25. doi: 10.1016/j.chemosphere.2016.02.084. Epub 2016 Mar 9. doi: 10.1007/s11356-015-5572-6. Epub 2015 Oct 21. doi: 10.1016/j.pestbp.2015.04.006. Epub 2015 May 8. doi: 10.1002/jssc.201401063. Epub 2015 Feb 4. doi: 10.1371/journal.pone.0101052. eCollection 2014.
    10: Mandal K, Sahoo SK, Battu RS, Singh B. Estimation of quizalofop ethyl residues in black gram (Vigna mungo L.) by gas liquid chromatography. Bull Environ Contam Toxicol. 2014 Jan;92(1):115-8. doi: 10.1007/s00128-013-1159-4. Epub 2013 Nov 26. doi: 10.1016/j.pestbp.2012.11.003. Epub 2012 Dec 3. Chinese. doi: 10.1080/10934529.2012.687175. doi: 10.1007/s10661-012-2662-5. Epub 2012 May 11. doi: 10.1002/chir.22053. Epub 2012 May 8. doi: 10.1007/s00216-011-4969-4. Epub 2011 Apr 13. doi: 10.1016/j.jhazmat.2010.11.081. Epub 2010 Nov 27. doi: 10.1016/j.chroma.2010.07.016. Epub 2010 Jul 16. doi: 10.1007/s00244-009-9382-z. Epub 2009 Sep 16. doi: 10.1007/s00128-009-9692-x. Epub 2009 Mar 17.

    合成参考文献


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