CAS: 765-85-5; Methyl Cyclobutanecarboxylate

相似化合物

3721-95-7 4415-82-1 2987-17-9

上下游产品

CAS号67-56-1 甲醇 | CAS号3721-95-7 环丁基甲酸 | CAS号186581-53-3 重氮甲烷 | CAS号120-92-3 环戊酮 | CAS号14924-53-9 环丁烷甲酸乙酯 | CAS号694-28-0 2-氯环戊酮 | CAS号50995-48-7 2,5-二溴戊酸甲酯 | CAS号5006-22-4 环丁基甲酰氯 | CAS号15324-42-2 2,2-二苯基环戊酮 | CAS号118431-89-3 3-环丁基-3-氧代丙腈 | CAS号1125702-76-2 1-Cyclobutyl-2-... | CAS号1432-53-7 [cyclobutyliden... | CAS号1485-98-9 1,1'-(1-Cyclope... | CAS号75621-39-5 1-甲基环丁烷羧酸甲酯 | CAS号640768-72-5 N-甲氧基-N-甲基环丁甲酰胺 | CAS号38401-41-1 (1-甲基环丁基)甲醇

环丁基甲酸,碳酸二甲酯置于diiron Nonacarbonyl体系中,化学反应 1.0H,以98%的收率获得产物环丁基甲酸甲酯
参考文献:锰和铁羰基的影响下脂肪族和芳香族羧酸与碳酸二甲酯的甲基化
标题:锰和铁羰基的影响下脂肪族和芳香族羧酸与碳酸二甲酯的甲基化
摘要:甲酯的合成是通过脂肪族和芳香族羧酸与碳酸二甲酯在锰和羰基铁的存在下反应进行的.已经发现以高收率合成羧酸甲酯的最佳催化剂和试剂比例以及其他条件.
DOI:10.1134/s1070363218010036

专利信息

专利号:US-11401273-B2
优先权日:2018-11-20
标题:Asymmetric synthesis of Azaspiro compounds
发明人：LELETI RAJENDER REDDY; WAMAN YOGESH; KALLURE PRIYA; BEGUM ZUBEDA; DIVYA THUMBAN; NALIVELA KUMARA SWAMY; VIJAY SAURABH; PARIKH PARANJAY; KOTTURI SHARADSRIKAR; PATEL CHIRAG; NAYAK KRISHNA; BAHAROONI KASIMRAZA; ZALAVADIYA VINKAL
权利人:PIRAMAL PHARMA LTD
摘要:The present invention relates to an improved asymmetric synthesis of azaspiro or diazaspiro compound (hereafter referred to as the compound 5, (5A) or (5N)) or their pharmaceutically acceptable salts and derivatives; through the formation of intermediate compounds 4, (4A) or (4N) respectively. The process comprises an unusual substrate specific highly diastereoselective as well as enantio-enriched 1-substituted 2-azaspiro[3.3]heptane or 1-substituted 2-diazaspiro[3.3]heptane compounds with high diastereoselectivity by addition of a cyclobutane carboxylate anion to a Davis-Ellman's imine, followed by reduction and cyclisation resulting in the selective formation of azaspiro or diazaspiro intermediate compound 4, (4A) or (4N); which on subsequently removing the sulfinyl group provides corresponding azaspiro or diazaspiro compound 5, (5A) or (5N) respectively.

专利号:US-2023303611-A1
优先权日:2022-01-21
标题:Synthesis of an antiviral azasugar triphosphate
发明人：KOTIAN PRAVIN L; Dang zhao; WU MINWAN
权利人:BIOCRYST PHARM INC
摘要:Provided are methods of making the active 5′-triphosphate form of galidesivir (compound 1) and the active 5′-triphosphate form of azasugar nucleoside analogues (compound 2):a potent anti-viral compound useful for broad spectrum treatment, suppression, and prevention of viral infections. The syntheses of compound 1 and compound 2 can be achieved via selective formation of protected intermediate 1b and protected intermediate 2b, respectively:

专利号:US-5942632-A
优先权日:1995-07-28
标题:Solid phase synthesis method
发明人：WANG GARY T
权利人:ABBOTT LAB
摘要:A solid phase synthesis method and intermediates useful in the process are disclosed for the preparation of diamino diol and diamino alcohol inhibitors of HIV protease.

专利号:US-4086423-A
优先权日:1973-10-12
标题 :Process for cephem synthesis
发明人：FIRESTONE RAYMOND A; RATCLIFFE RONALD W; CHRISTENSEN BURTON G
权利人:MERCK & CO INC
摘要:Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##

专利号:US-2022041609-A1
优先权日:2018-11-20
标题:An improved asymmetric synthesis of azaspiro compounds

专利号:US-8242142-B2
优先权日:2008-08-19
标题:Cyclohexylamines, phenylamines and uses thereof
发明人：LIN SHUO; YANG ZHEN
权利人:LIN SHUO; YANG ZHEN; UNIV CALIFORNIA; UNIV PEKING SHENZHEN GRAD SCHO
摘要:Compounds having the formula I, their methods of synthesis, and pharmaceutically acceptable salts of certain of them are provided in which the variables have the definitions described herein. n n n n n n n n n n Compositions including the compounds having the formula I-A in which the variables have the definitions described herein, and methods of using the compositions for the treatment of certain diseases mediated by the up-regulation of Smo are also disclosed.