专利号:US-6180830-B1 优先权日:1995-11-08 标题 :Method for preparing a bimetallic ruthenium/tin catalyst and a process for the synthesis of aldehydes 发明人:JACQUOT ROLAND 权利人:RHODIA CHIMIE SA 摘要:The present invention relates to a new process for the preparation of a bimetallic ruthenium/tin catalyst. The process for the preparation of a bimetallic ruthenium/tin catalyst according to the invention is characterised by the fact that it consists in carrying out the reduction of a ruthenium complex having an electrovalency of -4 and a coordination number of 6, the ligands being either a halogen atom or an anion or a tin halide. The catalyst is further employed for the preparation of aldehydes by reduction, in the vapor phase, of carboxylic acids, esters and anhydrides.
专利号:US-4764263-A 优先权日:1987-05-18 标 题:Electrochemical synthesis of substituted aromatic amines in basic media 发明人:GREGORY THOMAS D; STUTTS KENNETH J 权利人:DOW CHEMICAL CO 摘要:Substituted amino aromatic compounds such as 3-amino-4-hydroxybenzoic acid are prepared by electrolytically reducing the corresponding nitro aromatic compound in a basic medium at temperatures below 60° C. and current densities greater than 50 milliamps per square centimeter. The aminohydroxybenzoic acids are useful in the preparation of polybenzoxazoles which are used to make fibers and composites having high strength and thermal stability.
专利号:US-5476827-A 优先权日:1991-10-24 标题 :Process for the synthesis of aldehydes and their derivatives and catalyst for use thereof 发明人:FERRERO ROSE-MARIE; JACQUOT ROLAND 权利人:RHONE POULENC CHIMIE 摘要:A process for the preparation of aldehydes by hydrogen reduction of carboxylic acids, esters or anhydrides, characterized in that the reduction conducted in the vapor phase, in the presence of a bimetallic catalyst of the ruthenium/tin type.
专利号:US-2023295613-A1 优先权日:2020-02-14 标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming 发明人:JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J 权利人:UNIV NORTHWESTERN; UNIV ILLINOIS 摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
专利号:US-11814621-B2 优先权日:2018-06-01 标题 :Expanding the chemical substrates for genetic code reprogramming 发明人:JEWETT MICHAEL CHRISTOPHER; LEE JOONGOO; MOORE JEFFREY S; SCHWIETER KENNETH E; SCHWARZ KEVIN JEROME 权利人:UNIV NORTHWESTERN; UNIV ILLINOIS 摘要:Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
[参考文献]: Midori Natsume, Et Al. Inhibitory Effects Of Conjugated Epicatechin Metabolites On Peroxynitrite-Mediated Nitrotyrosine Formation. J Clin Biochem Nutr. 2008 Jan;42(1):50-3.
合成参考文献
参考文献:10.1007/s11426-025-2991-6 摘要:Qu M, Qiao M, Zhang F, Lei Y, Zhang N, Li S, Zhang X. A paddle-wheel pre-construction strategy towards benzoate-protected Cu28 nanoclusters with reshaped electronic landscape for the AAC click reaction. Sci. China Chem. 2025 Dec 09;69(4):1854–9. doi: 10.1007/s11426-025-2991-6.