CAS: 5457-28-3; 1H-Indole-3-Carbonitrile

上下游产品

3-甲基吲哚 3-Methylindole 83-34-1
吲哚-3-甲胺 3-Aminomethylindole 22259-53-6
3-吲哚甲醛 Indole-3-Carboxaldehyde 487-89-8
吲哚-3-甲醇 Indole-3-Carbinol 700-06-1
吲哚-3-甲醛肟 Indole-3-Carbaldoxime 04/05/2592
吲哚-3-甲醛肟 (E)-1H-Indole-3-Carbaldehyde Oxime 40747-04-4
芦竹碱 3-(Dimethylaminomethyl)Indole 87-52-5
1-(3-氯丙基)-3-氰基吲哚 1-(3-Chloropropyl)-3-Cyanoindole 156237-50-2
Indole-3-Carboxaldehyde N,N-Dimethylhydrazone 92487-36-0
Indole-3-Carbaldehyde Dimethylhydrazone 92487-36-0

吲哚-3-甲醇置于manganese(Iv) Oxide,氨,Magnesium Sulfate体系中,用 四氢呋喃,异丙醇 作为反应溶剂,化学反应 18.0H,以77%的收率获得产物3-氰基吲哚
参考文献:串联氧化工艺:活性醇直接转化为腈
标题:串联氧化工艺:活性醇直接转化为腈
摘要:据报道,在室温下使用二氧化锰和氨在含有硫酸镁的 2-丙醇-Thf 中将伯醇直接转化为腈(rcH2Oh 转化为 Rcn).这种通过原位氧化-亚胺化-醛亚胺氧化序列进行的转化已应用于一系列苄醇,杂环醇,烯丙醇和炔丙醇.
DOI:10.1055/s-2002-32950

专利信息

专利号:US-5990319-A
优先权日:1996-08-23
标 题 :Synthesis of bisindolylmaleimides
发明人：FAUL MARGARET MARY; WINNEROSKI JR LEONARD LARRY
权利人:LILLY CO ELI
摘要:The present invention provides for the reaction of optionally substituted indole-3-acetamides with optionally substituted methyl indole-3-glyoxyl reagent to prepare potent PKC inhibitors. The reaction is a very efficient and robust macrocyclization methodology.

专利号:EP-2053618-A1
优先权日:2007-10-25
标 题:A dye including an anchoring group in its molecular structure
发明人：FUHRMANN GERDA; NELLES GABRIELE; BAMEDI ZILAI AMENEH; YASUDA AKIO
权利人:SONY CORP
摘要:The present invention relates to a dye including an anchoring group in its structure, to a method of synthesis of such dye, to an electronic device comprising such dye, and to uses of such dye. Said anchoring group being represented by formula 1n nwherein attachment of said anchoring group within said molecular structure of said dye is at the terminal carbon marked with an asterisk in above formula, wherein nG is selected from -COOH, -SO 3 H, -PO 3 H 2 , -BO 2 H 2 , -SH, -OH, -NH 2 , preferably -COOH, wherein A is selected from the group comprising H, -CN, -NO 2 , -COOR, -COSR, -COR-, -CSR, -NCS, -CF 3 , -CONR 2 , -OCF 3 , C 6 H 5-m F m , wherein m = 1 - 5, nR being H or any straight or branched alkyl chain of general formula -C n H 2n+1 , n = 0 - 12, preferably 0-4, or any substituted or non-substituted phenyl or biphenyl.

专利号:WO-2020181931-A1
优先权日:2019-03-08
标 题:Heptamethine carboxylindole cyanine dye and preparation method and application therefor
发明人：LI JUAN; WU AIGUO; YUAN BO; JIANG ZHENQI
权利人:CIXI INSTITUTE OF BIOMEDICAL ENGINEERING NINGBO INSTITUTE OF INDUSTRIAL TECH CHINESE ACADEMY OF SCIE; NINGBO INSTITUTE OF MATERIALS TECH & ENGINEERING CHINESE ACADEMY OF SCIENCES
摘要:Disclosed in the present application are a heptamethine carboxylindole cyanine dye and a preparation method and an application therefor, relating to the field of polymethine indole cyanine dyes and the preparation thereof. The structural formula of the heptamethine carboxylindole cyanine dye is shown in formula (I); the dye has the properties of near infrared light absorption and fluorescence development, and can be used as a probe auxiliary agent. The method comprises the following steps: 1) reacting raw materials comprising a 2,3,3-trimethyl-carboxylindole derivative and a nucleophilic substitution compound in vacuum conditions at a rising temperature to obtain an organic ammonium salt; and 2) reacting a solution containing the organic ammonium salt obtained in step 1) and a cyclo-olefin derivative at a rising temperature in closed conditions. The method has the advantages of a short synthesis route, an environmentally friendly solvent, simple processing, high yield, high purity, and preventing noble metal catalysis, and has high applicability and can be used to synthesise products of various structural types.

专利号:EP-2112671-A1
优先权日:2008-04-23
标 题 :A dye including an anchoring group in its molecular structure
发明人：FUHRMANN GERDA; NELLES GABRIELE; BAMEDI ZILAI AMENEH; YASUDA AKIO
权利人:SONY CORP
摘要:The present invention relates to a dye including an anchoring group in its structure, to a method of synthesis of such dye, to an electronic device comprising such dye, and to uses of such dye.

专利号:US-5948907-A
优先权日:1996-08-23
标题:Synthesis of bisindolylmaleimides

专利号:US-2017158858-A9
优先权日:2013-03-07
标 题:Cyanine compounds
发明人：HERMANSON GREG; CZERNEY PETER T; DESAI SURBHI; WENZEL MATTHIAS S; DWORECKI BOGUSLAWA R; LEHMANN FRANK G
权利人:HERMANSON GREG; CZERNEY PETER T; DESAI SURBHI; WENZEL MATTHIAS S; DWORECKI BOGUSLAWA R; LEHMANN FRANK G
摘要:Compounds used as labels with properties comparable to known fluorescent compounds. The compounds can be conjugated to proteins and nucleic acids for biological imaging and analysis. Synthesis of the compounds, formation and use of the conjugated compounds, and specific non-limiting examples of each are provided.