CAS: 5394-13-8; 2-Bromobenzo[b]Thiophene

上下游产品

benzothiophen-2-yllithium diethyl ether bromine methanol 2-(piperidin-1-yl)-1-benzothiophene 2-(4-methoxyphenyl)benzo[b]thiophene 2,2'-bibenzo[b]thiophene 2,3-dihydrobenzo(b)thiophene

苯并噻吩置于sodium 2,2,6,6-Tetramethylpiperidide,1,1,2,2-四溴乙烷体系中,用 正己烷 作为反应溶剂,化学反应 1.5H,以81%的收率获得产物2-溴苯并噻吩
参考文献:2,2,6,6-四甲基哌啶钠的无锂合成及其合成应用
标题:2,2,6,6-四甲基哌啶钠的无锂合成及其合成应用
摘要:已经开发了使用钠分散液作为唯一钠源的无锂合成方法制备2,2,6,6-四甲基哌啶钠(natmp).制备的natmp用作brønsted碱,与litmp的反应性表现出一些差异.
DOI:10.1002/adsc.201900215

专利信息

专利号:US-9074050-B2
优先权日:2011-05-30
标 题 :Process for the production of polymers by using coupling reactions
发明人：KLEINER MATTHIAS; ELBS MARTIN; KASTLER MARCEL
权利人:KLEINER MATTHIAS; ELBS MARTIN; KASTLER MARCEL; BASF SE
摘要:The present invention relates to a continuous process for the production of polymeric coupling products by using a reactor assembly which is equipped with two or more reaction cells. The educt fluid is pumped through the reaction cells and thoroughly mixed therein by means of agitators. Preferably the process according to the invention is used for the preparation of coupling products which show at least partially precipitation and/or gelation effects during the performance of the synthesis. The precipitation and/or gelation effects are associated with and increase of the viscosity of the reaction system under reaction conditions. The products which are obtained by the process according to the invention have increased molecular weight and low polydispersity over similar products which were obtained in batch experiments.

专利号:US-9370515-B2
优先权日:2013-03-07
标题 :Mixed lineage kinase inhibitors and method of treatments
发明人：GOODFELLOW VAL S; NGUYEN THONG X; RAVULA SATHEESH B; GELBARD HARRIS A
权利人:CALIFIA BIO INC; UNIV ROCHESTER
摘要:Provided herein are imidazopyridine compounds having an inhibitory effect on mixed lineage kinases (MLKs), methods of their synthesis, and methods of their therapeutic. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and pharmaceutical compositions.

专利号:US-11332462-B2
优先权日:2012-02-08
标 题 :Heteroaryl compounds and methods of use thereof
发明人：CAMPBELL JOHN EMMERSON; CAMPBELL UNA; HANANIA TALEEN G; SHAO LIMING
权利人:SUNOVION PHARMACEUTICALS INC; PGI DRUG DISCOVERY LLC
摘要:Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.

专利号:CN-118221736-A
优先权日:2022-12-19
标 题 :Synthesis method of bis (2-benzothienyl) phosphorus chloride

专利号:CN-112500390-A
优先权日:2020-11-20
标 题:A kind of organic hole transport material and its synthesis method and perovskite battery

专利号:CN-114605378-B
优先权日:2022-03-24
标 题 :A kind of thiophene fused ring compound and its synthesis method and application