CAS: 524-83-4; Etybenzatropine
该化合物是属于三氯苯衍生物类别的化学化合物,主要因其抗胆碱基特性而得到承认,有助于治疗各种医疗条件,特别是管理与帕金森病和其他运动紊乱有关的症状.该化合物的特征包括一种结构,包括一种具有许多抗胆碱基制剂特征的三氯丙烯环.乙基苯甲酸通常在制药环境中施用,并可能表现出减少肌肉僵硬性和激素等效应.其作用机制涉及抑制肌肉受体的乙酰胆碱,导致某些途径的...
- 英文名称Etybenzatropine
- 中文名称乙苯托品
- IUPAC名称3alpha-(Diphenylmethoxy)-8-ethyl-1alphaH,5alphaH-nortropane
- 其它别名1aH,5aH-Nortropane, 3a-(diphenylmethoxy)-8-ethyl- (8CI); 8-Azabicyclo[3.2.1]°Ctane, 3-(diphenylmethoxy)-8-ethyl-, endo-; 3-(Diphenylmethoxy)-8-ethyl-8-azabicyclo[3.2.1]°Ctane; 3-(Diphenylmethoxy)-8-ethylnortropane; Ethybenztropine; Ethylbenztropine; Etybenzatropine; N-Ethyl-8-aza-3-bicyclo[3.2.1]°Ctyl benzhydryl ether; N-Ethylbenztropine; N-Ethylnortropine benzhydryl ether; Panolid; Ponalid; Ponalide; Tropethydrylin
- CAS编号524-83-4
- MFCD编号:MFCD00865155
- FDA UNII编号:G1X2X9N95N
- 分子式:C22H27NO分子量:321.461
- 产品CID: 1513966
- 同类组份化合物CAS24815-25-6 (HBr)524-83-4 (free base)26598-44-7 (HCl)
- 产品分类原料药 → 神经系统用药 → 拟胆碱药
物理性质
MSDS等安全信息
上下游产品
Bromodiphenylmethane N-ethylnorpseudotropine diazodiphenylmethane °Ctan-3-olendo-8-ethyl-8-azabicyclo3.2.1°Ctan-3-ol合成工艺路线路线简述
📜二苯基重氮甲烷,Endo-8-Ethyl-8-Azabicyclo[3.2.1]octan-3-Ol 在 苯体系中,获得 Etybenzatropine
参考文献:关于6-烷氧基tropines和n-烷基nortropines的二芳基甲烷衍生物.12.关于生物碱合成的交流
标题:关于6-烷氧基tropines和n-烷基nortropines的二芳基甲烷衍生物.12.关于生物碱合成的交流
摘要:描述了二芳基甲基醚,苯甲酸酰胺的醚和托烷衍生物的二芳基甲基胺的合成.一些新化合物显示出抗胆碱能和组胺抑制作用.
Doi:10.1002/Hlca.19590420717
海关参考信息
- 2902300000-甲苯
2905122000-异丙醇
2906210000-苄醇
2905142000-仲丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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专利信息
专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Zakrzewska F. [Direct M motor response in calf muscles during post-tetanic potentiation (PTP) of monosynaptic H reflex before and following administration of ethybenztropine in drug-induced muscle rigidity]. Neurol Neurochir Pol. 1974 Sep-Oct;8(5):719-28. Polish.
合成参考文献
摘要:Psychotropic Drugs and Related Compounds, 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972, -(228), 1972
参考文献:10.2165/00002512-199914050-00002
摘要:Durif F. Treating and preventing levodopa-induced dyskinesias: current and future strategies. Drugs Aging. 1999 May;14(5):337–45. doi: 10.2165/00002512-199914050-00002.
参考文献:10.2165/00003495-199448020-00009
摘要:Grant S, Fitton A. Risperidone. A review of its pharmacology and therapeutic potential in the treatment of schizophrenia. Drugs. 1994 Aug;48(2):253–73. doi: 10.2165/00003495-199448020-00009.
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