CAS: 466-96-6; Pseudocodeine

英文名称Pseudocodeine
其它别名(5alpha,8beta)-6,7-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-8-ol; 6,7-Didehydro-4,5α-epoxy-3-methoxy-17-methylmorphinan-8β-ol; Neois°Codeine
CAS编号466-96-6
EINECS号:207-380-9
FDA UNII编号:73786Q1Q4G
分子式:C18H21NO3分子量:299.15213
产品CID: 2278760

相似结构搜索
InChIKey: KYIVACLUFRUFLS-CVXFFHBFSA-N
1S/C18H21NO3/c1-19-8-7-18-14-6-4-12(20)16(18)11(19)9-10-3-5-13(21-2)17(22-14)15(10)18/h3-6,11-12,14,16,20H,7-9H2,1-2H3/t11-,12+,14+,16-,18-/m1/s1
计算化学: 氢键受体数4.0氢键供体数1.0可旋转键数1.0

物理性质

LogP:1.8

MSDS等安全信息

合成工艺路线路线简述

海关参考信息

2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2902700000-异丙基苯
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-8450365-B2
优先权日:2009-05-12
标题 :Efficient synthesis of galanthamine
发明人：MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ
权利人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ; UNIV TEXAS
摘要:The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.

专利号:US-2015133664-A1
优先权日:2012-06-07
标题:Chemical transformations of (-)-codeine to afford derivatives of codeine and morphine thereof
发明人：MAGNUS PHILIP; GHAVIMI-ALAGHA BAHMAN
权利人:UNIV TEXAS
摘要:The present invention relates to methods for the synthesis of morphine, codeine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency, steroselectivity, and overall yield of said codeine and morphine related derivatives and intermediates thereof. The present invention relates to new codeine and morphine related derivative compositions.

专利号:US-4089855-A
优先权日:1976-04-23
标题:Process for the stereoselective reduction of 6- and 8-keto morphine and morphinan derivatives with formamidinesulfinic acid and compounds obtained thereby
发明人：CHATTERJIE NITHIANANDA; INTURRISI CHARLES E
权利人:CORNELL RES FOUNDATION INC
摘要:Process for the stereoselective synthesis of 6Î²-and 8Î²- hydroxy epimers by the chemical reduction of 6- and 8-keto derivatives in the morphine and morphinan series utilizing alkaline formamidinesulficic acid. The 6Î²- and 8Î²-hydroxy derivatives obtained according to the invention evidence narcotic antagonist and/or agonist activity and are also useful in the chemical and pharmacological standardization of various morphine and codeine derivatives and metabolites.

专利号:US-2010292475-A1
优先权日:2009-05-12
标题 :Efficient Synthesis Of Morphine And Codeine

专利号:US-8293927-B2
优先权日:2009-05-12
标题 :Efficient synthesis of morphine and codeine

专利号:WO-2010132570-A1
优先权日:2009-05-12
标题:Synthesis of morphine and related derivatives