CAS: 34846-64-5; 3-Cyanoquinoline

相似化合物

13669-42-6 6480-68-8 35509-27-4

上下游产品

CAS号5332-24-1 3-溴喹啉 | CAS号143-33-9 氰化钠 | CAS号151-50-8 氰化钾 | CAS号591250-21-4 2-[acetyloxymet... | CAS号557-21-1 氰化锌 | CAS号79476-07-6 3-碘喹啉 | CAS号544-92-3 氰化亚铜 | CAS号612-58-8 3-甲基喹啉 | CAS号552-89-6 邻硝基苯甲醛 | CAS号95104-21-5 2-氯喹啉-3-甲腈 | CAS号91-22-5 喹啉 | CAS号299423-78-2 quinoline-3-car... | CAS号6480-68-8 喹啉-3-羧酸 | CAS号53951-84-1 3-喹啉甲酸甲酯 | CAS号13669-42-6 3-喹啉甲醛 | CAS号6480-67-7 quinoline-3-car... | CAS号72594-76-4 1-methyl-4H-qui... | CAS号85749-95-7 1-benzyl-2H-qui... | CAS号87861-96-9 1-[[4-(trifluor...

📜3-乙炔喹啉置于2-甲基吡啶氧化物,亚硝酸特丁酯体系中,用 四氢呋喃 用作溶剂,以86%的收率获得3-氰基喹啉
参考文献:使用叔丁基亚硝酸盐从炔烃中制得的芳基腈:无金属方法裂解c≡c键
标题:使用叔丁基亚硝酸盐从炔烃中制得的芳基腈:无金属方法裂解c≡c键
摘要:炔烃复分解之外的炔烃c≡c键断裂仍然是反应发现中一个不发达的领域.最近,据报道氮化可以使炔烃生成腈.报道了用于末端炔烃的无金属c≡c键裂解以产生腈的新方案.这种方法提供了一个机会来合成范围广泛的包含芳基,杂芳基和天然产物衍生物的腈(38个例子).另外,证明了t Buono用作末端芳基炔烃的强大氮化剂的潜力.
Doi:10.1021/acs.Orglett.6B00147

专利信息

专利号:US-7126025-B2
优先权日:2003-01-21
标 题 :Synthesis of 4-(amino)-2-butenoyl chlorides and their use in the preparation of 3-cyano quinolines
发明人：CONSIDINE JOHN LEO; DAIGNEAULT SYLVAIN; CHEW WARREN; IERA SILVIO; DUNCAN SCOTT MASON; REN JIANXIN
权利人:WYETH CORP
摘要:This invention provides a compound of Formula (I): n nwhereinn S 1 and S 2 are each independently, hydrogen, alkyl, alkenyl, alkynyl, aralkyl, substituted or unsubstituted aryl, and S 1 and S 2 together with the nitrogen to which they are attached form a nitrogen containing heteroaryl and a pharmaceutically acceptable salt thereof; a method of preparing the compound of Formula (I), and use of the compound of Formula (I) in the preparation of 3-cyano quinolines.

专利号:US-2007208164-A1
优先权日:2006-02-27
标题:Methods of synthesizing radiolabeled 3-cyano[14C]quinolines
发明人：OLSZEWSKI JOHN D; MAY MICHAEL K; BERGER DAN M
权利人:WYETH CORP
摘要:The present invention is directed to radiolabeled 3-cyanoquinolines of the formula: n n nand methods of synthesizing the same, wherein G 1 , G 2 R 1 , R 4 , Z, X, and n are as defined herein. n nThe present invention is also directed to a radiolabeled intermediate compounds of formula (VII): n n nwherein PG, G 1 , R 1 , R 4 , R 10 , and R 11 are as defined herein, and synthesis of the same.

专利号:US-7294740-B2
优先权日:2002-02-05
标 题:Process for the synthesis of N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids
发明人：DUNCAN SCOTT MASON; OSUMA AUGUSTINE TOBI; DAIGNEAULT SYLVAIN; BERNATCHEZ MICHEL
权利人:WYETH CORP
摘要:The invention claimed herein provides a process to oxidize N-(5-alkoxy-2-methyl-4-nitrophenyl)acetamides to N-acyl-2-amino-4-alkoxy-5-nitrobenzoic acids using potassium permanganate in the presence of magnesium sulfate in aqueous sulfolane or aqueous pyridine.

专利号:WO-2017135901-A1
优先权日:2016-02-05
标题 :Heterocyclic compounds, methods of synthesis and uses thereof
发明人：CHUA BOON TIN; KERI GYORGY; ORFI LASZLO; Németh Gábor; WÃ?CZEK FRIGYES; Varga Zoltán; MARKO PETER
权利人:AGENCY SCIENCE TECH & RES; VICHEM CHEMIE RES LTD
摘要:The present invention relates to 3-quinolinecarbonitrile compounds of formula (I) disclosed herein, methods for their synthesis, and uses thereof. Advantageously, the disclosed heterocyclic compounds may demonstrate enhanced efficacy in antitumor properties. Hence, the present disclosure also relates to the use of the disclosed 3-quinolinecarbonitrile compounds or pharmaceutical compositions thereof in cancer treatment.

专利号:US-2004162442-A1
优先权日:2003-01-21
标 题 :Synthesis of 4-(amino)-2-butenoyl chlorides and their use in the preparation of 3-cyano quinolines

专利号:CA-2514550-A1
优先权日:2003-01-21
标题:Synthesis of 4amino-2-butenoyl chlorides and their use in the preparation of 3-cyano quinolines