CAS: 3196-73-4; Methyl 3-Aminopropanoate Hydrochloride

上下游产品

CAS号67-56-1 甲醇 | CAS号107-95-9 β-丙氨酸 | CAS号3303-84-2 B°C-beta-丙氨酸 | CAS号50835-77-3 3-异氰酰基丙酸甲酯 | CAS号3729-19-9 3-Is°Cyanatopro... | CAS号4138-35-6 3-氨基丙酸甲酯 | CAS号51513-29-2 甲基丙二酰胺 | CAS号18967-35-6 3-异硫氰基丙酸甲酯 | CAS号754125-43-4 3-(环戊基氨基)丙酸甲酯 | CAS号107-95-9 β-丙氨酸 | CAS号90558-39-7 3-(2-NITRO-BENZ... | CAS号42116-55-2 3-((叔丁氧基羰基)氨基)丙酸甲酯 | CAS号4874-18-4 3-氨基-n-甲基丙酰胺

氰乙酸甲酯置于氢气,Potassium Hydroxide体系中,用 甲醇 用作溶剂,30.0 °C,2.0 Mpa 条件下,反应 2.0H,以98.6%的收率获得3-氨基丙酸甲酯盐酸盐
参考文献:一种β-丙氨酸酯类化合物的制备方法
标题:一种β-丙氨酸酯类化合物的制备方法
摘要:本发明属于化工技术领域,具体涉及一种β‑丙氨酸酯类化合物的制备方法,包括如下步骤:A)将氰乙酸酯在溶剂ⅰ中溶解,加入碱性物质和雷尼镍进行催化加氢反应,反应结束后过滤并将滤液浓缩,得产物a;B)将产物a溶解于溶剂ⅱ中,滴加氯化氢的溶剂ⅱ溶液,当体系ph值为2~3后,停止滴加,得混合液b;C)将混合液b浓缩,减压干燥,得目标产物.采用上述方案,利用氰乙酸酯催化氢化制备氨基酸衍生物,操作简单,条件温和,对设备要求低,投入成本低;原料易得,且价格较低,降低了运营成本;反应物转化率高,产物收率高,适合工业化大规模生产.

专利信息

专利号:US-2011124634-A1
优先权日:2008-05-13
标 题:Bioactive compounds for treatment of cancer and neurodegenerative diseases
发明人：SUN CONNIE L; LI XIAOYUAN
权利人:PONIARD PHARMACEUTICALS INC
摘要:The invention provides bioactive compounds for the treatment of various malconditions such as cancer and neurodegenerative diseases including Alzheimer's disease. The chemical compounds as disclosed herein are found to show bioactivity in bioassays related to these conditions. Pharmaceutical compositions, combinations and methods of synthesis are provided, as are methods of using the compound, compositions and combinations in the treatment of the diseases.

专利号:CN-1687068-A
优先权日:2005-03-31
标 题 :Total synthesis of brominated derivatives of pyrrole heterocyclic alkaloid aldisin

专利号:US-9321728-B2
优先权日:2012-04-25
标题:Beta-alanine derivatives, pharmaceutically acceptable salts thereof, and pharmaceutical composition comprising same as active ingredient
发明人：AHN JIN HEE; PAGIRE H S; RHEE SANG DAL; KIM KI YOUNG; JUNG WON HOON; BAE MYUNG-AE; SONG JIN SOOK; KIM KWANG-ROK; KWAK HYUN JUNG
权利人:KOREA RES INST CHEM TECH; HANDOK PHARMACEUTICALS CO LTD
摘要:The present invention relates to a beta-alanine derivative, pharmaceutically acceptable salts thereof, and a pharmaceutical composition including the same as an active ingredient. The novel beta-alanine derivative and pharmaceutically acceptable salts thereof according to the present invention may effectively inhibit the activity of DGAT1, which is an enzyme serving as a catalyst in the final step of the synthesis of neutral lipids, to thereby be effectively used as a pharmaceutical composition for preventing or treating various lipid metabolism-related disorders selected from the group consisting of obesity, dyslipidemia, fatty liver, insulin resistance syndrome, and hepatitis.

专利号:CN-107217048-A
优先权日:2017-07-10
标 题:A kind of aminopeptidase that catalyzes the synthesis of carnosine and its preparation method and application

专利号:JP-2012529533-A
优先权日:2009-06-11
标题 :Synthesis of 6-α-amino N-substituted morphinans by catalytic hydrogen transfer

专利号:JP-2015057448-A
优先权日:2009-06-11
标 题:Synthesis of 6-α-amino N-substituted morphinans by catalytic hydrogen transfer