CAS: 22082-99-1; 2-(4-Bromophenyl)Naphthalene

上下游产品

1,4-bromoiodobenzene naphthalene-2-boronic acid 2-bromonaphthalene 1.4-dibromobenzene 3-Hydroxy-3-(4-naphth-2-yl-phenyl)piperidine 9-(4-(naphthalen-2-yl)phenyl)anthracene 4-(naphthalene-2-yl)phenylboronic acid pinacol ester 3,5-dimethyl-2-(4-naphthalen-2-yl-phenyl)pyrazine

3-(4-溴苯基)-1-(2-(2-甲氧基乙烯基)苯基)丙-2-炔-1-醇置于(乙腈)[(2-联苯)二叔丁基膦]六氟锑酸金(I)体系中,用 二氯甲烷 用作溶剂,化学反应 0.08H,以91%的收率获得2-(4-溴苯基)萘
参考文献:Gold-Catalyzed Annulation/fragmentation: Formation Of Free Gold Carbenes By Retro-Cyclopropanation
标题:Gold-Catalyzed Annulation/fragmentation: Formation Of Free Gold Carbenes By Retro-Cyclopropanation
摘要:The Gold(I)-Catalyzed Cyclization Of 1-(Prop-2-Yn-1-yl)-2-Alkenylbenzenes Substituted At The Benzylic Position With Or Groups Gives 1,3-Disubstituted Naphthalenes With Concomitant Fragmentation Of The Alkene. One Of These Annulations Proceeds By A Retro-Cyclopropanation That Leads To Free Gold(I) Carbenes.
Doi:10.1021/ja104743K

专利信息

专利号:US-5556990-A
优先权日:1994-12-16
标 题:Polyarylcarbamoylaza- and -carbamoylalkanedioic acids
发明人：PAULS HENRY W; CHOI YONG-MI; STUDT ROBERT W; MAGUIRE MARTIN P; SPADA ALFRED P; CHA DON D
权利人:RHONE POULENC RORER PHARMA
摘要:This invention relates to a class of novel dicarboxy amide derivatives of lipophilic amines which exhibit squalene synthase inhibition properties. More specifically the compounds are bis-aryl and/or heteroaryl alkyl or cycloalkylamino dicarboxy amides. Compounds of this invention reduce levels of serum cholesterol in the body without significantly reducing mevalonic metabolite synthesis. This invention relates also to pharmacological compositions and method of treatment for lowering serum cholesterol levels using the compounds of this invention.