CAS: 183013-07-2; 1-Methoxycarbonyloxy-Pentane

上下游产品

pentan-1-ol carbonic acid dimethyl ester methanol carbon dioxide

📜戊醇,碳酸二甲酯置于novozyme 435体系中,化学反应 36.0H,以94.3%的收率获得甲基戊基碳酸酯
参考文献:Asymmetric Organic Carbonate Synthesis Catalyzed By An Enzyme With Dimethyl Carbonate: A Fruitful Sustainable Alliance
标题:Asymmetric Organic Carbonate Synthesis Catalyzed By An Enzyme With Dimethyl Carbonate: A Fruitful Sustainable Alliance
摘要:我们成功开发了一种简单高效的生物过程,通过在本工作中进行novozym 435介导的dmc和醇的酯化反应,实现了不对称有机碳酸酯的合成.在优化条件下(60°C,醇与dmc的摩尔比为1:12),碳酸酯的最高产率可达到95.6%.新工艺的另一个优点是,酶在经过九次回收后仍保留90%的原始活性.因此,它有潜力成为工业生产不对称有机碳酸酯的有效酶催化工艺.
Doi:10.1039/c3Ra43698E

专利信息

专利号:US-7521478-B2
优先权日:2002-07-30
标 题 :Total synthesis of myriaporones
发明人：DEL POZO LOSADA CARLOS; FRANCESCH ANDRES; MARCHANTE CARMEN CUEVAS; ALVAREZ MARTA PEREZ
权利人:PHARMA MAR SAU
摘要:Compounds of the general formula (I) or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof are provided: wherein the substituent groups defined by R are each independently selected from the group consisting of H, SiR′ 3 , SOR′, SO 2 X, C(â•?O)R′, C(â•?O)OR′, C(â•?O)NR′, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aryl, heteroaryl or aralkyl; the group R′ is selected from substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, aminoalkyl, aryl, aralkyl and heterocyclic groups; and the group R″ is selected from the group consisting of H, OH, OR′, OCOR′, SH, SR′, SOR′, SO 2 R′, NO 2 , NH 2 , NHR′, N(R′) 2 , NHCOR′, N(COR′) 2 , NHSO 2 R′, CN, halogen, C(â•?O)H, C(â•?O)R′, CO 2 H, CO 2 R′, CH 2 OR, substituted or unsubstituted alkyl, substituted or unsubstituted haloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkylidene, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl and substituted or unsubstituted heteroaromatic; with the proviso that the compound is not compound 1, 3 or 4 of U.S. Pat.No. 5,514,708. The compounds have antitumour activity. A synthetic route is also provided.

专利号:US-4452968-A
优先权日:1981-11-30
标题 :Synthesis of polycarbonate from dialkyl carbonate and bisphenol diester
发明人：BOLON DONALD A; HALLGREN JOHN E
权利人:GEN ELECTRIC
摘要:Polycarbonates are formed by the interaction of a bisphenol diester, carbon monoxide and oxygen. The initial polycarbonate product is an oligomer which, upon heat treatment, polymerizes to a high molecular weight polycarbonate. The products produced according to the present invention are chainstopped prior to heat treatment, making them less thermally and oxidatively sensitive.

专利号:US-2008269511-A2
优先权日:2002-07-30
标题 :Total Synthesis of Myriaporones

专利号:EP-1532139-B1
优先权日:2002-07-30
标题 :Total synthesis of myriaporones

专利号:US-2006084819-A1
优先权日:2002-07-30
标 题 :Total synthesis of myriaporones

专利号:CN-102826946-A
优先权日:2012-09-07
标题 :A green synthesis process of aryl methyl subcarbonate