CAS: 17071-62-4; 1,3-Adamantanedimethanol

相似化合物

39269-10-8 770-71-8 1334415-43-8

上下游产品

CAS号39269-10-8 1,3-金刚烷二甲酸 | CAS号41826-65-7 adamantane-1,3-... | CAS号1459-95-6 1,3-金刚烷二甲酸甲酯 | CAS号50-00-0 甲醛 | CAS号23174-58-5 1,3-Diiodoadamantane | CAS号281-23-2 金刚烷

金刚烷置于lithium Aluminium Tetrahydride,氯化亚砜,硫酸,溴,铁粉,Silver Nitrate体系中,用 四氢呋喃 用作溶剂,化学反应 37.0H,反应生成1,3-金刚烷二甲醇
参考文献:新型简化的eleutherobin类似物作为潜在的抗肿瘤药物的合成和细胞毒性.
标题:新型简化的eleutherobin类似物作为潜在的抗肿瘤药物的合成和细胞毒性.
摘要:使用分子对接技术分析包含紫杉醇和eleutherobin药效团部分的混合简化结构,并基于金刚烷和8-氧杂双环[3.2.1]辛烷骨架进行合成.讨论了取代基的立体化学在生物活性中的关键作用.在微摩尔浓度下,所选的类似物会在体外和在活生物体中干扰微管蛋白动力学.此外,新化合物对人肿瘤细胞系具有细胞毒性.简化的eleutherobin类似物可被视为新型抗肿瘤药物的原型.
Doi:10.1039/c8Ob02915F

专利信息

专利号:CN-110982054-B
优先权日:2019-12-28
标题 :A composite catalyst for catalyzing synthesis of polycarbonate and method for catalyzing synthesis of polycarbonate

专利号:CN-110982054-A
优先权日:2019-12-28
标 题 :A composite catalyst for catalyzing synthesis of polycarbonate and method for catalyzing synthesis of polycarbonate

专利号:US-2012122923-A1
优先权日:2006-06-13
标 题:Dual molecules containing a peroxide derivative, their synthesis and therapeutic uses
发明人：COSLEDAN FREDERIC; MEUNIER BERNARD; PELLET ALAIN
权利人:COSLEDAN FREDERIC; MEUNIER BERNARD; PELLET ALAIN; SANOFI AVENTIS; PALUMED SA; CENTRE NAT RECH SCIENT
摘要:The invention concerns dual molecules corresponding to formula (I): in which: A represents a molecular residue with antimalarial activity of formula (IIa) or (IIIa) or a residue facilitating bioavailability; B represents a cycloalkyl group potentially substituted, or B represents a bi- or tricyclic group capable of being substituted, or B represents 2 cycloalkyl groups linked together through either a single bond or an alkylene chain; m and n represent independently of one another 0, 1 or 2; R 5 represents a hydrogen atom, an alkyl, cycloalkyl or C 1-3 -alkylene-cycloakyl group; Z 1 and Z 2 represent an alkyl radical, the group Z 1 +Z 2 +C i +C j representing a mono- or polycyclic structure, with one of the Z 1 or Z 2 being able to represent a single bond; R 1 and R 2 , identical or different, represent a hydrogen atom or a functional group capable of increasing hydrosolubility; R x and R y forming together a cyclic peroxide including 4 to 8 links and including 1 or 2 additional oxygen atoms in the cyclic structure, possibly substituted by one or more R 3 groups; as a base or a salt to be added to an acid, as a hydrate or solvate, in racemic form, isomers and their mixtures, in addition to their diasteroisomers and their mixtures. Preparation method and use as medications with antimalarial activity.

专利号:CN-119081096-A
优先权日:2024-08-07
标 题:Catalyst, preparation method and application thereof in synthesis of polycarbonate diol

专利号:WO-2019077230-A1
优先权日:2017-10-16
标题:MULTIBLOCK POLYMERS THE SYNTHESIS USES OF OLIGOCARBONATES POLYOLS

专利号:CN-119390956-A
优先权日:2024-11-05
标题:Synthesis method and application of polyethylene naphthalate copolymer