专利号:US-2008312430-A1 优先权日:2004-10-20 标题:Method of Preparing or Synthesizing Polyazamacrocycle Derivatives 发明人:CIHELNIK SIMON; DROZ LADISLAV; SRAMEK MARTIN 权利人:THERAPHARM GMBH 摘要:The present invention relates to novel processes for the synthesis of polyazamacrocycle derivatives. Furthermore, the present invention relates to novel polyazamacrocycle derivatives as well as novel intermediates for the synthesis of said polyazamacrocycle derivatives.
专利号:US-2009162290-A1 优先权日:2005-09-09 标 题 :Method for the synthesis of penta-pendant enantiomer-pure chelators and process for therapeutically active bioconjugates preparation by a covalent binding thereof 发明人:BENES IVAN; CIHELNIK SIMON; DROZ LADISLAV; SRAMEK MARTIN 权利人:THERAPHARM GMBH 摘要:The present invention provides a method for synthesis and binding methods of pentapendant enantiomer-pure chelators of formula (VII) wherein R 1 , R 2 , R 3 , R 4 are groups forming an adequate enantiomer of the chelator; and X 1 -X 5 , Y 1 -Y 5 , Z 1 -Z 5 each individually forming pendant chelating groups.
专利号:US-9102961-B2 优先权日:2009-03-11 标 题 :Biological synthesis of difunctional hexanes and pentanes from carbohydrate feedstocks 发明人:BAYNES BRIAN M; GEREMIA JOHN MICHAEL; LIPPOW SHAUN M 权利人:CELEXION LLC 摘要:Provided herein are methods for the production of difunctional alkanes in microorganisms. Also provided are enzymes and nucleic acids encoding such enzymes, associated with the difunctional alkane production from carbohydrates feedstocks in microorganisms. The invention also provides recombinant microorganisms and metabolic pathways for the production of difunctional alkanes.
专利号:US-10851407-B2 优先权日:2014-05-08 标题:Left-handed gamma-peptide nucleic acids, methods of synthesis and uses therefor 发明人:LY DANITH H; HSIEH WEI-CHE; SACUI IULIA; MANNA ARUNAVA 权利人:UNIV CARNEGIE MELLON 摘要:A method of making optically pure preparations of chiral γPNA (gamma peptide nucleic acid) monomers is provided. Nano structures comprising chiral γPNA structures also are provided. Methods of amplifying and detecting specific nucleic acids, including in situ methods are provided as well as compositions and kits useful in those methods. Lastly, methods of converting nucleobase sequences from right-handed helical PNA, nucleic acid and nucleic acid analog structures to left-handed γPNA, and vice-versa, are provided.
专利号:US-2013017593-A1 优先权日:2009-03-11 标题:Biological Synthesis of Difunctional Hexanes and Pentanes from Carbohydrate Feedstocks
专利号:EP-1942949-A1 优先权日:2005-09-09 标 题 :Method for the synthesis of pentapendant enantiomer-pure chelators and process for therapeutically active bio-conjugates preparation by a covalent binding of thereof
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