CAS: 1198-69-2; (3R,4R,5R)-5-((R)-1,2-Dihydroxyethyl)-3,4-Dihydroxydihydrofuran-2(3H)-One
该化合物是D-甘酸产生的环状酯,是一种在水中溶解的白对白结晶粉,在各种应用中都有用.该化合物以其微酸特性著称,经常被用作食品添加剂,特别是防腐剂和酸剂.在化妆品行业,D-甘醇内酯是一种发泡剂和发泡剂,促进皮肤水合和改善质.它因其抗氧化性特性而得到承认,有助于保护细胞免受氧化性压力.D-甘醇内酯被林业局归类为GIS(普遍公认的安全性)物质,表明食品消费的安全性.此外,它可以参与Maillard反应,促进食品加工的口味发展.
- 英文名称(3R,4R,5R)-5-((R)-1,2-Dihydroxyethyl)-3,4-Dihydroxydihydrofuran-2(3H)-One
- 中文名称D-葡萄糖酸-1,4-内酯
- IUPAC名称(3R,4R,5R)-5-((R)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one
- 其它别名(3R,4R,5R)-5-((R)-1,2-二羟基乙基)-3,4-二羟基二氢呋喃-2(3H)-酮
- CAS编号1198-69-2
- MFCD编号:MFCD00080784
- FDA UNII编号:F62S8J9R28
- 分子式:C6H10O6分子量:178.14
- 产品CID: 264100
- 产品分类有机原料→生命科学→糖类
相似化合物
22430-23-5 1128-23-0 6322-07-2物理性质
MSDS等安全信息
上下游产品
gluconic acid D-Glucono-1,5-lactone D-Glucose methanolarabino-[2]hexulosonic acid methyl esterD-arabino-[2]hexulosonic acid methyl ester N-phenyl-D-gluconamide D-sorbitol D-idono-1,4-lactone合成工艺路线路线简述
- 合成目标产物 D-Gluconic Acid, .Gamma.-Lactone 主要起始原料 Gluconic Acid
- 526-95-4 = 1198-69-2 + 90-80-2
反应条件:1.1R:48 H,120°C
标题:Synthesis Of Modified Lignin As An Antiplasticizer For Strengthening Poly(Vinyl Alcohol)-Lignin Interactions Toward Quality Gel-Spun Fibers
作者:By Lin,Jiaxian Et Al
参考文献:Acs Applied Polymer Materials 日期:2022 卷标:4(3) 页码:1595-1607
📜(3R,4S,5R)-5-((R)-2,2,7,7-Tetramethyl-3,6-Dioxa-2,7-Disilaoctan-4-yl)-3,4-Bis((Trimethylsilyl)Oxy)Dihydrofuran-2(3H)-One置于potassium Fluoride体系中,用 甲醇 用作溶剂,化学反应 5.25H,以96.6%的收率获得(3R,4R,5R)-5-[(1R)-1,2-二羟基乙基]-3,4-二羟基四氢呋喃-2-酮
参考文献:一种d-葡萄糖酸-γ-内酯及其中间体的制备方法
标题:一种d-葡萄糖酸-γ-内酯及其中间体的制备方法
摘要:本发明公开了一种d‑葡萄糖酸‑γ‑内酯及其中间体的制备方法,属于医药化工技术领域,本方法以葡萄糖内酯为起始物料,在碱性试剂条件下与硅烷试剂反应得到高纯度的固体d‑葡萄糖酸‑γ‑内酯中间体;然后在酸性或氟化物的条件下,脱掉硅烷保护基得到d‑葡萄糖酸‑γ‑内酯.本发明提供的制备方法所需原料及试剂便宜,成本低廉,操作简捷安全,收率高,产率稳定,同时环境污染小,有很好的经济效应,适宜工业生产.
海关参考信息
- 2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-7652172-B2
优先权日:2004-09-20
标题:Expeditious synthesis of DPD
发明人：SEMMELHACK MARTIN F; CAMPAGNA SHAWN R; BASSLER BONNIE L; FEDERLE MICHAEL J
权利人:UNIV PRINCETON
摘要:This invention provides a practical synthesis route for 4,5-dihydroxypentane-2,3-dione (DPD), an unstable small molecule which is proposed to be the source of universal signaling agents for quorum sensing in bacteria. The synthesis route includes new intermediates and allows preparation of isotopically-labeled DPD and ent-DPD. The method provides sufficient quantities of DPD for study of spontaneous binding of borate to DPD, the signal for the marine bacteria V. harveyi.
专利号:US-2006084800-A1
优先权日:2004-06-30
标 题 :Synthesis of aldonolactones, aldarolactones, and aldarodilactones using azeotropic distillation
发明人：CHENAULT HENRY K
权利人:CHENAULT HENRY K
摘要:Processes for making lactones and dilactones from aldaric acids, aldonic acids, and their corresponding salts by dehydrative cyclization and azeotropic distillation. The processes can be carried out in the presence of water because water is removed by azeotropic distillation.
专利号:WO-2006005071-A1
优先权日:2004-06-30
标题:Synthesis of aldonolactones, aldarolactones, and aldarodilactones using azeotrophic distillation
发明人：CHENAULT H KEITH
权利人:DU PONT; CHENAULT H KEITH
摘要:Processes for making lactones and dilactones from aldaric acids, aldonic acids, and their corresponding salts by dehydrative cyclization and azeotropic distillation. The processes can be carried out in the presence of water because water is removed by azeotropic distillation.
专利号:US-2006084817-A1
优先权日:2004-06-30
标 题 :Synthesis of aldonolactones, aldarolactones, and aldarodilactones using gas sparging
发明人：CHENAULT HENRY K
权利人:CHENAULT HENRY K
摘要:Aldaric acids, aldonic acids, and their corresponding salts are cyclized to the corresponding lactone or dilactone using gas sparging to remove water.
专利号:US-2009018368-A1
优先权日:2004-09-20
标 题:Expeditious synthesis of dpd
专利号:EP-1639121-A4
优先权日:2003-06-30
标题:SYNTHESIS OF BETA-L-2-DESOXYNUCLEOSIDES
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Synthesis Of Beta-L-2'-Deoxy Nucleosides摘要:An Improved Process For The Preparation Of 2′-Modified Nucleosides And 2′-Deoxy-Nucleosides, Such As, β-L-2′-Deoxy-Thymidine (Ldt), Is Provided. In Particular, The Improved Process Is Directed To The Synthesis Of A 2′-Deoxynucleoside That May Utilize Different Starting Materials But That Proceeds Via A Chloro-Sugar Intermediate Or Via A 2,2′-Anhydro-1-Furanosyl-Nucleobase Intermediate. Where An 2,2′-Anhydro- 1 -Furanosyl Base Intermediate Is Utilized, A Reducing Agent, Such As Red-Al, And A Sequestering Agent, Such As 15-Crown-5 Ether, That Cause An Intramolecular Displacement Reaction And Formation Of The Desired Nucleoside Product In Good Yields Are Employed. An Alternative Process Of The Present Invention Utilizes A 2,2′-Anhydro-1-Furanosyl Base Intermediate Without A Sequestering Agent To Afford 2′-Deoxynucleosides In Good Yields. The Compounds Made According To The Present Invention May Be Used As Intermediates In The Preparation Of Other Nucleoside Analogues, Or May Be Used Directly As Antiviral And/or Antineoplastic Agents.
合成参考文献
参考文献:10.1021/bm025512f
摘要:Ogawa K, Nakajima-Kambe T, Nakahara T, Kokufuta E. Coimmobilization of gluconolactonase with glucose oxidase for improvement in kinetic property of enzymatically induced volume collapse in ionic gels. Biomacromolecules. 2002 May;3(3):625–31. doi: 10.1021/bm025512f.
参考文献:10.1021/ol0491890
摘要:Liu KG, Yan S, Wu YL, Yao ZJ. Synthesis of 4-azido-4-deoxy-Neu5,7,8,9Ac42en1Me. A key intermediate for the synthesis of GG167 from D-glucono-delta-lactone. Org Lett. 2004 Jun 24;6(13):2269–72. doi: 10.1021/ol0491890.
参考文献:10.1093/mp/ssp105
摘要:Korn M, Gärtner T, Erban A, Kopka J, Selbig J, Hincha DK. Predicting Arabidopsis freezing tolerance and heterosis in freezing tolerance from metabolite composition. Mol Plant. 2010 Jan;3(1):224–35.
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