上下游产品
carbamimidoyl-amidosulfuric acid dicyanodiamidine sulfate phenylhydrazine bis(trimethylsilyl)sulphate2-amino-5-(4-chlorophenyl)-6-ethylpyrimidin-4(3H)-one 4-thiophen-2-yl-6-trifluoromethyl-pyrimidin-2-ylamine 2-amino-6-methyl-4-(trifluoromethyl)pyrimidine 2-amino-4-phenyl-6-(trifluoromethyl)pyrimidine 专利信息
专利号:EP-2905293-A1
优先权日:2013-12-09
标 题:Process for catalytic synthesis of low-carbon polyether-based compound by using acidic ionic liquid
发明人:XIA CHUNGU; LI ZHEN; CHEN JING
权利人:LANZHOU CHEM PHYS INST; SUZHOU OST ADVANCED MATERIALS CO LTD
摘要:The present invention relates to a process for catalytic synthesis of a low-carbon polyether-based compound by using an acidic ionic liquid as the catalyst. The low-carbon polyether-based compound is prepared from an acetal compound and paraformaldehyde under the following conditions: reaction temperature of 70°C-200°C and reaction pressure of 0.2MPa-6MPa. The process is mainly characterized by avoiding the use of concentrated sulfuric acid or trifluoromethanesulfonic acid, which has strong corrosivity and will pollute the environment, as the catalyst. The ionic liquid being used has no corrosivity and will not pollute the environment, and has high selectivity for the low-carbon polyether-based compound product. Outstanding characteristics of the process include: the reaction system is free of water, the product can be very easily separated from the catalyst, the product can be widely applied, the ionic liquid can be used repeatedly, and therefore the outlook of the use of the process on industrial scale is very good.
专利号:US-9738647-B2
优先权日:2009-12-24
标题:Methods for the synthesis of polycyclic guanidine compounds
发明人:GRIDNEV ALEXEI
权利人:NOVOMER INC; SAUDI ARAMCO TECH CO
摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.
专利号:US-11584724-B2
优先权日:2018-04-23
标 题:Process for synthesis of a phenoxy diaminopyrimidine compound
发明人:MALONEY KEVIN M; BASU KALLOL; DI MASO MICHAEL JAMES; HUMPHREY GUY R; LEE ALFRED Y; PENG FENG; REN HONG; ZHANG SIWEI
权利人:MERCK SHARP & DOHME; WERTHENSTEIN BIOPHARMA GMBH; MERCK SHARP & DOHME LLC
摘要:Disclosed herein is a novel process for preparing Compound A free base, 5-((2,4-diaminopyrimidin-5-yl)oxy)-4-iso-propyl-2-methoxybenzenesulfonamide, and a citrate salt of Compound A with simplified chemistry and a high overall yield: Compound A. In one embodiment, the overall yield from the starting material 2-isopropylphenol to Compound A citrate salt is greater than 50%. In another embodiment, the overall yield is greater than 60%. Also disclosed herein are novel salts and solvates of Compound A.
专利号:US-2011105797-A1
优先权日:2009-11-02
标题:Creatinol sulfate and synthesis method thereof
发明人:ZHANG GUOJI; ZHANG JIASHU
权利人:TIANJIN TIANCHENG PHARMACEUTICAL CO LTD
摘要:A chemical compound of creatinol sulfate is formed by chemically reacting N-methyl-amino-ethanol, cyanamide, with sulfuric acid to produce the creatinol sulfate with relatively higher yield rate and purity, wherein the mol ratio of N-methyl-amino-ethanol, sulfuric acid, and cyanamide is approximately 2:1:2.
专利号:US-2012259112-A1
优先权日:2009-12-24
标题:Methods for the synthesis of polycyclic guanidine compounds
专利号:CN-114835581-A
优先权日:2022-03-10
标题 :Synthesis of p-methoxycinnamate by synergistic catalysis of small molecule free guanidine and N-methyl-2-pyrrolidone