CAS: 1184-68-5; Guanidiniumsulphate

该化合物是一种有机化合物,其特点是有坚固的基底瓜尼丁,与硫酸离子并存,通常看起来像是白色晶状固体,在水中高度溶解,便于用于各种用途;该化合物以其作为生物化学和药物研究试剂的作用而著称,特别是在蛋白脱硫和稳定过程中;Guanidine硫酸盐也可在某些生物系统中作为氮源;其特性包括一种相对较高的熔点和在标准条件下的稳定性,尽管由于它的潜在毒性和刺激作用,应当谨慎处理它;在实验室环境中,它经常被用于分子生物学协议,包括涉及核酸的协议;

结构式图片

上下游产品

carbamimidoyl-amidosulfuric acid dicyanodiamidine sulfate phenylhydrazine bis(trimethylsilyl)sulphate2-amino-5-(4-chlorophenyl)-6-ethylpyrimidin-4(3H)-one 4-thiophen-2-yl-6-trifluoromethyl-pyrimidin-2-ylamine 2-amino-6-methyl-4-(trifluoromethyl)pyrimidine 2-amino-4-phenyl-6-(trifluoromethyl)pyrimidine

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    专利信息


    专利号:EP-2905293-A1
    优先权日:2013-12-09
    标 题:Process for catalytic synthesis of low-carbon polyether-based compound by using acidic ionic liquid
    发明人:XIA CHUNGU; LI ZHEN; CHEN JING
    权利人:LANZHOU CHEM PHYS INST; SUZHOU OST ADVANCED MATERIALS CO LTD
    摘要:The present invention relates to a process for catalytic synthesis of a low-carbon polyether-based compound by using an acidic ionic liquid as the catalyst. The low-carbon polyether-based compound is prepared from an acetal compound and paraformaldehyde under the following conditions: reaction temperature of 70°C-200°C and reaction pressure of 0.2MPa-6MPa. The process is mainly characterized by avoiding the use of concentrated sulfuric acid or trifluoromethanesulfonic acid, which has strong corrosivity and will pollute the environment, as the catalyst. The ionic liquid being used has no corrosivity and will not pollute the environment, and has high selectivity for the low-carbon polyether-based compound product. Outstanding characteristics of the process include: the reaction system is free of water, the product can be very easily separated from the catalyst, the product can be widely applied, the ionic liquid can be used repeatedly, and therefore the outlook of the use of the process on industrial scale is very good.

    专利号:US-9738647-B2
    优先权日:2009-12-24
    标题:Methods for the synthesis of polycyclic guanidine compounds
    发明人:GRIDNEV ALEXEI
    权利人:NOVOMER INC; SAUDI ARAMCO TECH CO
    摘要:The present invention provides methods for the synthesis of polycyclic guanidine compounds. In certain embodiments, provided methods include the step of contacting a described reagent with a triamine compound to provide a polycyclic guanidine compound.

    专利号:US-11584724-B2
    优先权日:2018-04-23
    标 题:Process for synthesis of a phenoxy diaminopyrimidine compound
    发明人:MALONEY KEVIN M; BASU KALLOL; DI MASO MICHAEL JAMES; HUMPHREY GUY R; LEE ALFRED Y; PENG FENG; REN HONG; ZHANG SIWEI
    权利人:MERCK SHARP & DOHME; WERTHENSTEIN BIOPHARMA GMBH; MERCK SHARP & DOHME LLC
    摘要:Disclosed herein is a novel process for preparing Compound A free base, 5-((2,4-diaminopyrimidin-5-yl)oxy)-4-iso-propyl-2-methoxybenzenesulfonamide, and a citrate salt of Compound A with simplified chemistry and a high overall yield: Compound A. In one embodiment, the overall yield from the starting material 2-isopropylphenol to Compound A citrate salt is greater than 50%. In another embodiment, the overall yield is greater than 60%. Also disclosed herein are novel salts and solvates of Compound A.

    专利号:US-2011105797-A1
    优先权日:2009-11-02
    标题:Creatinol sulfate and synthesis method thereof
    发明人:ZHANG GUOJI; ZHANG JIASHU
    权利人:TIANJIN TIANCHENG PHARMACEUTICAL CO LTD
    摘要:A chemical compound of creatinol sulfate is formed by chemically reacting N-methyl-amino-ethanol, cyanamide, with sulfuric acid to produce the creatinol sulfate with relatively higher yield rate and purity, wherein the mol ratio of N-methyl-amino-ethanol, sulfuric acid, and cyanamide is approximately 2:1:2.

    专利号:US-2012259112-A1
    优先权日:2009-12-24
    标题:Methods for the synthesis of polycyclic guanidine compounds

    专利号:CN-114835581-A
    优先权日:2022-03-10
    标题 :Synthesis of p-methoxycinnamate by synergistic catalysis of small molecule free guanidine and N-methyl-2-pyrrolidone
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    摘要:von Angerer, S., Science of Synthesis Knowledge Updates, (2011) 1, 193.
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