CAS: 939986-65-9; 6-Chloropyrimidine-4-Carbonitrile
该化合物是一种多用途的七环化合物,在4号位置上用一个环球组取代了氯基,使该化合物成为有机合成中的宝贵中间体,特别是在制药,农用化学品和特殊化学品的制作方面.活氯和硝基三联联体能够选择性地发挥作用,便利复杂的分子框架的构建.其高纯度和稳定性确保核循环替代和交叉反应的一贯性.该化合物在药用化学中特别有助于开发以湿米丁为基础的抑制剂和离心剂.建议,在受控制的条件下进行适当处理,因为其具有再活动性.
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37131-91-2 81333-06-4 26293-93-6物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
N,N-dimethyl-anilineN,N-dimethyl-aniline 6-hydroxy-pyrimidine-4-carbaldehyde oxime 6-hydroxy-4-pyrimidinecarboxamide ethyl 6-oxo-3,6-dihydropyrimidine-4-carboxylate合成工艺路线路线简述
- 98024-63-6 = 939986-65-9
反应条件:1.1 Reagents: Phosphorus Oxychloride; 16 H,Reflux1.2 Reagents: Ammonium Hydroxide Solvents: Water; Neutralized,Cooled
标题:Pyrimidine-4-Carboxamide Compounds Useful As Raf Kinase Inhibitors And Their Preparation And Use In The Treatment Of Raf-Mediated Diseases
参考文献:World Intellectual Property Organization]
1370442-07-1 = 939986-65-9
反应条件:1.1 Reagents: Phosphorus Oxychloride; 30 Min,40 °C; 30 Min,60 °C; 1 H,80 °C1.2 Solvents: N,N-Dimethylaniline; 1 H,80 °C; 80 °C -> 0 °C1.3 Reagents: Water; Cooled
标题:Preparation Of 2-Aminopyridine-3-Carboxamides As Remedies For Angiogenesis Mediated Diseases
参考文献:United States]
42839-04-3 = 939986-65-9
反应条件:1.1 Reagents: Chlorosuccinimide Solvents: Dimethylformamide; Rt -> 75 °C
标题:Preparation Of Ibrutinib
参考文献:China]
98024-63-6 = 939986-65-9
反应条件:1.1 Reagents: Phosphorus Oxychloride; 18 H,Reflux; Reflux -> Rt1.2 Reagents: Water; 0 °C
标题:Preparation Of (3-Phenylisoxazolidin-2-Yl)(Piperidin-4-Yl)Methanone Derivative As Kinase Inhibitor
参考文献:Korea]
98024-63-6 = 939986-65-9
反应条件:1.1 Reagents: Phosphorus Oxychloride; 18 H,Reflux; Reflux -> Rt1.2 Reagents: Water; Cooled1.3 Reagents: Ammonia; Neutralized
标题:Indoles And Azaindoles As Alpha 7 Nicotinic Acetylcholine Receptor Modulators And Their Preparation And Use In The Treatment Of Diseases
参考文献:World Intellectual Property Organization]
= 939986-65-9 [标题:Reaction Conditions
标题:Indole And Azaindole Modulators Of The Alpha 7 Nachr
参考文献:United States
📜6-羟基-嘧啶-4-甲醛肟置于三氯氧磷,N,N-二甲基苯胺体系中,化学反应 3.0H,反应生成 6-氯-4-嘧啶甲腈
参考文献:Substituted Alkylamine Derivatives And Methods Of Use
标题:Substituted Alkylamine Derivatives And Methods Of Use
摘要:选定的胺对预防治疗疾病有效,如血管反应生成介导的疾病.本发明包括新的化合物,类似物,前药和药用可接受的盐,药物组合物和预防治疗疾病和其他疾病或状况的方法,包括癌症等.本发明还涉及制造这类化合物的过程以及在此类过程中有用的中间体.
海关参考信息
- 2926909090-其他腈基化合物
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