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📜(Z)-溴富马酸 反应生成 溴代马来酸酐
参考文献:Fittig; Petri,Justus Liebigs Annalen Der Chemie,1879,Vol. 195,P. 67
标题:Fittig; Petri,Justus Liebigs Annalen Der Chemie,1879,Vol. 195,P. 67

专利信息

专利号:US-5424421-A
优先权日:1990-07-17
标 题:Synthesis of carminic acid and principal intermediates
发明人：TYMAN JOHN H P; FIECCHI ALBERTO
权利人:EUROP COLOUR PLC
摘要:The invention relates to the synthesis of 6-deoxykermesates, 6-deoxykermesic acid, and carminic acid, based on a reaction of a 2-halogenonapthazarin with a bis-trimethylsilyl-diene.

专利号:US-9243002-B2
优先权日:2013-02-07
标题 :Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis C
发明人：DAI XING; LIU HONG; PALANI ANANDAN; HE SHUWEN; BROCKUNIER LINDA L; NARGUND RAVI; MARCANTONIO KAREN; ZORN NICOLAS; XIAO DONG; PENG XUANJIA; LI PENG; GUO TAO
权利人:MERCK SHARP & DOHME
摘要:The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-5322954-A
优先权日:1993-05-28
标 题 :Synthesis of 4-substituted phthalic anhydrides
发明人：SEPER KARL W; STULTS JEFFREY S; OLSEN GARY H
权利人:OCCIDENTAL CHEM CO
摘要:Disclosed is a method of making a 4-substituted phthalic anhydride. A halomaleic (including halofumaric anhydride (or the acid or ester thereof) is made by the reaction of-maleic anhydride with chlorine or bromine. The halomaleic anhydride is reacted with a conjugated diene to form a first cycloadduct having the formula ##STR1## The first cycloadduct is heated to eliminate HX and produce a second cycloadduct having the formula ##STR2## The second cyclo adduct is dehydrogenated to produce a 4substituted phthalic anhydride which has the formula ##STR3## where R 1 , R 2 , and R 4 are preferably H and R 3 is preferably Cl or F.

专利号:MX-2013007745-A
优先权日:2013-07-02
标题 :Synthesis of a derivative of 5-aminosalicilic acid with antioxidant activity.

专利号:WO-9201664-A1
优先权日:1990-07-17
标题:Synthesis of carminic acid and principal intermediates

专利号:EP-0602027-B1
优先权日:1990-07-17
标题 :Synthesis of carminic acid and principal intermediates