CAS: 495-60-3; (-)-Zingiberene

该化合物是一种主要存在于姜类基本油类中的松树脂碳氢化合物(Zingiber officinale),其特点是独特的芳香特性,有助于生姜的辣味,木质香味.由于分子式C15H24, 乙烷具有显著的稳定性和低波动性,因此适合在口味,香味和芳香疗法行业应用.它的亲脂性能很容易地融入基于脂质的配方.Zingibene还研究其潜在的生物活性特性,包括抗炎和抗氧化作用.作为一种天然衍生化合物,它与对药物和化妆品中可持续和植物成分的需求相一致.

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3-异丙基-6-亚甲基-1-环己烯 Beta-Phellandrene 555-10-2

合成工艺路线路线简述

    📜(5R,1's)-Epoxyzingiberene置于碳酸氢钠,间氯过氧苯甲酸体系中,用 水 作为反应溶剂,化学反应生成 α-姜烯
    参考文献:破译稻蝽,黄蝽(半翅目,蝽科)信息素混合物中 Murgantiol 异构体的绝对构型
    标题:破译稻蝽,黄蝽(半翅目,蝽科)信息素混合物中 Murgantiol 异构体的绝对构型
    摘要:Mormidea V-Uteum (半翅目,蝽科)的雄性产生的信息素混合物由两种异构体姜烯醇 (1) 和三种异构体 Murgantiol (2) 组成.虽然已经描述了姜烯醇异构体的绝对构型,但 Murgantiol 异构体的构型仍未被探索.因此,我们的目标是确定信息素混合物中 Murgantiol 异构体 (2 A-C) 的绝对构型.为了实现这一目标,我们首先对天然提取物进行脱水,然后进行对映体拆分,结果,三种异构体被鉴定为 (4 R,1' S)-Murgantiol.通过利用所有信息素成分之间固定的顺式和反式关系,我们建立了异构体2A和2B在c-1处的构型为s,而2C的构型为r.最后,利用微化学sharples不对称二羟基化和环氧化物闭环,我们确定了环氧化物环的绝对构型.因此,天然异构体2A,2B和2C被鉴定为(1S,4R,1 'S,4'R)-,(
    DOI:10.1002/cbdv.202301860

    海关参考信息

    专利信息


    专利号:US-9943544-B2
    优先权日:2015-03-18
    标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer
    发明人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
    权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH
    摘要:The present invention is a process for bio synthesis of nano arsenic trioxide defined by its low toxicity, higher bio availability and nano particle size with the aid of buttermilk, goat urine, dolichos biflorous and other plant materials such as ginger, momordica charantia and musa paradisiaca . The invention is carried out in different steps involving purification of crude form of arsenic trioxide by boiling it with buttermilk, goat urine and extract of dolichos biflorous in subsequent steps, followed by the trituration of the bio purified arsenic trioxide with extracts of ginger and momordica charantia in subsequent steps and heating of the dry product obtained after trituration with musa paradisiaca resulting in the production of novel nano arsenic trioxide. The product is effective in the treatment of various diseases including different types of cancer in animals and humans. The product obtained through the process is less toxic with higher bio availability.

    专利号:EP-3178313-A1
    优先权日:2015-12-09
    标题:Gene and protein for the synthesis of oxidized zingiberene derivatives
    权利人:LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE
    摘要:The invention provides a nucleic acid encoding an enzyme capable of producing 9-hydroxy-7-epi-zingiberene and 10,11-epoxy-9-hydroxy-7-epizingiberene from 7-epi-zingiberene. The invention further provides novel zingiberene derivatives that can be used for increasing pest resistance of plants.

    专利号:US-2022372509-A1
    优先权日:2019-08-23
    标题:Brown marmorated and harlequin stink bug pheromone enzyme synthesis and uses thereof
    发明人:THOLL DOROTHEA; LANCASTER JASON
    权利人:VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIV
    摘要:Described herein are engineered polynucleotides and vectors capable of encoding one or more engineered harlequin and/or brown marmorated stink bug pheromone synthesis enzymes. Also described herein are engineered harlequin and/or brown marmorated stink bug pheromone synthesis enzymes. Also described herein are methods of making modified plants capable of expressing one or more harlequin and/or brown marmorated stink bug pheromone synthesis enzymes.

    专利号:US-8257754-B2
    优先权日:2002-10-21
    标 题:Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response
    发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE M
    权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE M; METAPROTEOMICS LLC
    摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.

    专利号:US-8486457-B2
    优先权日:2002-10-21
    标 题:Compositions that treat or inhibit pathological conditions associated with inflammatory response
    发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE
    权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE; METAPROTEOMICS LLC
    摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.

    专利号:US-8557306-B2
    优先权日:2001-06-20
    标 题 :Compositions that treat or inhibit pathological conditions associated with inflammatory response
    发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE
    权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE; METAPROTEOMICS LLC
    摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献

    参考标题:Construction Of Two Vicinal Quaternary Carbons By Asymmetric Allylic Alkylation: Total Synthesis Of Hyperolactone C And (−)-Biyouyanagin A
    作者:Chao Du,Liqi Li,Ying Li,Zhixiang Xie |发布日期:2009.10.5
    摘要:Call On Triple A: Palladium‐catalyzed Asymmetric Allylic Alkylation (Pd‐aaa; See Scheme) Has Enabled A Concise And Efficient Synthesis Of Hyperolactone C And (−)‐biyouyanagin A In Only Six (20 % Overall Yield) And Seven (8 % Overall Yield) Steps, Respectively. The Enantiomers Of These Natural Products Were Also Prepared By Exploiting The Same Methodology.

    合成参考文献


    参考文献:10.1016/j.jpba.2006.07.034
    摘要:Qin NY, Yang FQ, Wang YT, Li SP. Quantitative determination of eight components in rhizome (Jianghuang) and tuberous root (Yujin) of Curcuma longa using pressurized liquid extraction and gas chromatography–mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2007 Jan;43(2):486–92. doi: 10.1016/j.jpba.2006.07.034.
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