专利号:US-9943544-B2 优先权日:2015-03-18 标 题:Process for bio synthesis of nano arsenic trioxide and its use in treatment of diseases including cancer 发明人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH 权利人:BENDALE YOGESH NARAYAN; BENDALE VINEETA YOGESH 摘要:The present invention is a process for bio synthesis of nano arsenic trioxide defined by its low toxicity, higher bio availability and nano particle size with the aid of buttermilk, goat urine, dolichos biflorous and other plant materials such as ginger, momordica charantia and musa paradisiaca . The invention is carried out in different steps involving purification of crude form of arsenic trioxide by boiling it with buttermilk, goat urine and extract of dolichos biflorous in subsequent steps, followed by the trituration of the bio purified arsenic trioxide with extracts of ginger and momordica charantia in subsequent steps and heating of the dry product obtained after trituration with musa paradisiaca resulting in the production of novel nano arsenic trioxide. The product is effective in the treatment of various diseases including different types of cancer in animals and humans. The product obtained through the process is less toxic with higher bio availability.
专利号:EP-3178313-A1 优先权日:2015-12-09 标题:Gene and protein for the synthesis of oxidized zingiberene derivatives 权利人:LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE 摘要:The invention provides a nucleic acid encoding an enzyme capable of producing 9-hydroxy-7-epi-zingiberene and 10,11-epoxy-9-hydroxy-7-epizingiberene from 7-epi-zingiberene. The invention further provides novel zingiberene derivatives that can be used for increasing pest resistance of plants.
专利号:US-2022372509-A1 优先权日:2019-08-23 标题:Brown marmorated and harlequin stink bug pheromone enzyme synthesis and uses thereof 发明人:THOLL DOROTHEA; LANCASTER JASON 权利人:VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIV 摘要:Described herein are engineered polynucleotides and vectors capable of encoding one or more engineered harlequin and/or brown marmorated stink bug pheromone synthesis enzymes. Also described herein are engineered harlequin and/or brown marmorated stink bug pheromone synthesis enzymes. Also described herein are methods of making modified plants capable of expressing one or more harlequin and/or brown marmorated stink bug pheromone synthesis enzymes.
专利号:US-8257754-B2 优先权日:2002-10-21 标 题:Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response 发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE M 权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE M; METAPROTEOMICS LLC 摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
专利号:US-8486457-B2 优先权日:2002-10-21 标 题:Compositions that treat or inhibit pathological conditions associated with inflammatory response 发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE 权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE; METAPROTEOMICS LLC 摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
专利号:US-8557306-B2 优先权日:2001-06-20 标 题 :Compositions that treat or inhibit pathological conditions associated with inflammatory response 发明人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE 权利人:TRIPP MATTHEW L; BABISH JOHN G; BLAND JEFFREY S; DARLAND GARY K; LERMAN ROBERT; LUKACZER DANIEL O; LISKA DEANN J; HOWELL TERRENCE; METAPROTEOMICS LLC 摘要:A natural formulation of compounds that would to modulate inflammation is disclosed. The formulation would also inhibit expression of COX-2, inhibit synthesis of prostaglandins selectively in target cells, and inhibit inflammatory response selectively in target cells. The compositions containing at least one fraction isolated or derived from hops. Other embodiments relate to combinations of components, including at least one fraction isolated or derived from hops, tryptanthrin and conjugates thereof, rosemary, an extract or compound derived from rosemary, a triterpene species, or a diterpene lactone or derivatives or conjugates thereof.
参考标题:Construction Of Two Vicinal Quaternary Carbons By Asymmetric Allylic Alkylation: Total Synthesis Of Hyperolactone C And (−)-Biyouyanagin A 作者:Chao Du,Liqi Li,Ying Li,Zhixiang Xie |发布日期:2009.10.5 摘要:Call On Triple A: Palladium‐catalyzed Asymmetric Allylic Alkylation (Pd‐aaa; See Scheme) Has Enabled A Concise And Efficient Synthesis Of Hyperolactone C And (−)‐biyouyanagin A In Only Six (20 % Overall Yield) And Seven (8 % Overall Yield) Steps, Respectively. The Enantiomers Of These Natural Products Were Also Prepared By Exploiting The Same Methodology.
合成参考文献
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