CAS: 45798-01-4; 4-Methylpiperazine-1-Carboximidamide

相似化合物

77723-03-6 1208081-65-5 84727-42-4

上下游产品

CAS号109-01-3 N-甲基哌嗪 | CAS号4023-02-3 1H-吡唑-1-甲脒盐酸盐 | CAS号867-44-7 |S|-甲基异硫脲硫酸盐 | CAS号861429-91-6 4-methylpiperaz...

📜4-Methylpiperazine-1-Carboxamidine Hydrochloride置于sodium Ethanolate体系中,用 乙醇 作为反应溶剂,化学反应 0.5H,反应生成 4-甲基哌嗪-1-羧脒
参考文献:ber N1-Und N2-Substituierte 2-Amino-5,6-Dihydro-4(1H)-Pyrimidinone
标题:ber N1-Und N2-Substituierte 2-Amino-5,6-Dihydro-4(1H)-Pyrimidinone
摘要:
DOI:10.1007/bf00798460

专利信息

专利号:US-8653282-B2
优先权日:2007-10-18
标 题:Preparation of dihydrothieno [3,2-D] pyrimidines and intermediates used therein
发明人：FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G
权利人:FRUTOS ROGELIO; KRISHNAMURTHY DHILEEPKUMAR; MULDER JASON ALAN; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; TAMPONE THOMAS G; BOEHRINGER INGELHEIM INT
摘要:The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO 2 , preferably SO, and wherein R A , R 1 , R 2 , R 3 , R 4 and R 5 have the meanings given in the description. The methods according to this invention are more suitable for large-scale synthesis of said compounds than prior methods because the new synthetic process avoids distillation and chromatographic purification between steps and results in a higher overall yield of the desired product.

专利号:US-9550000-B2
优先权日:2011-09-09
标题 :Compositions, methods, and systems for the synthesis and use of imaging agents
发明人：ROBINSON SIMON P; YU MING
权利人:ROBINSON SIMON P; YU MING; LANTHEUS MEDICAL IMAGING INC
摘要:The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the imaging agent is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs. In some embodiments, methods and compositions for assessing perfusion and innervation mismatch in a portion of a subject are provided.

专利号:EP-3567029-A1
优先权日:2011-09-09
标 题:Compositions, methods, and systems for the synthesis and use of imaging agents

专利号:US-2020397927-A1
优先权日:2011-09-09
标题:Compositions, methods, and systems for the synthesis and use of imaging agents

专利号:US-2014328756-A1
优先权日:2011-09-09
标题:Compositions, methods, and systems for the synthesis and use of imaging agents

专利号:JP-2018008952-A
优先权日:2011-09-09
标 题:Compositions, methods and systems for the synthesis and use of contrast agents