CAS: 34837-55-3; Phenyl Hypobromoselenoite

该化合物是一种有机合成中广泛用作多用途电子生殖性试剂的有机化合物,其关键优点包括:在闪烁反应中具有高度的回活动性,使藻类,烷烷和碳基化合物能够高效地功能化;该试剂对于选择性的精选精选和氧化性变异具有特别宝贵的价值,对视像选择性和立体化学提供了精确的控制;它还作为其他苯乙烯衍生物的前体;苯乙烯基溴在无水条件下稳定,在普通有机溶剂中表现出良好的溶解性,便于合成应用的处理;该试剂在建立C-Se债券方面非常有用,因此成为制药,农用化学和材料科学研究的宝贵工具.

结构式图片

相似化合物

645-96-5 104013-25-4 1261861-19-1

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

phenyl selen°Cyanate benzeneselenenyl tribromide phenyl methyl selenide dibromide ethylphenylselenium dibromideethyl phenyl selenide o-nitrophenyl phenylselenyl sulfide p-methoxyphenyl phenyl selenide benzyl phenyl selenide

合成工艺路线路线简述

    📜4,4-Dimethyl-3,5-Diphenyl-4,5-Dihydroisoxazol-5-Ol 反应生成 苯基溴化硒
    参考文献:Edwards Et Al.,Journal Of The Chemical Society,1928,P. 2300
    标题:Edwards Et Al.,Journal Of The Chemical Society,1928,P. 2300

    海关参考信息

    专利信息


    专利号:US-2006287520-A1
    优先权日:2005-05-16
    标 题 :Synthesis of salinosporamide A and analogues thereof
    发明人:DANISHEFSKY SAMUEL J; ENDO ATSUSHI
    权利人:DANISHEFSKY SAMUEL J; ENDO ATSUSHI
    摘要:A novel synthesis of salinosporamide A is provided. Salinospoamide A as well as structurally related natural products, omuralide and lactacystin, have been shown to be proteasome inhibitors. Therefore, these compounds as well as analogues of these natural products may be useful in the treatment of proliferative diseases such as cancer, autoimmune diseases, diabetic retinopathy, etc. The invention provides for the synthesis of salinosporamide A as well as analogs thereof using a convenient point for derivatization of the bicyclic core. Pharmaceutical compositions and method of using the inventive compounds are also provided.

    专利号:US-6005097-A
    优先权日:1996-06-14
    标题 :Processes for high-yield diastereoselective synthesis of dideoxynucleosides
    发明人:CHEN SHU-HUI; LI XIUYAN
    权利人:VION PHARMACEUTICALS INC
    摘要:The present invention relates to methods for substantially enhancing the stereoselective synthesis of β-anomeric nucleoside analogs. In methods according to the present invention, the introduction of a phenylseleno group onto a blocked lactone sugar precursor may be selected so that the desirable phenylseleno substituent is introduced on the side of the blocked lactone away from the blocking group. This stereospecific introduction of the phenylseleno group in sugar precursor allows the synthesis of nucleoside analogs and in particular, 2',3',-dideoxy- and 2',3'-dideoxy-2',3'-didehydronucleoside analogs in very high yield. In certain preferred embodiments, the preferred phenylseleno blocked lactone is obtained in an amount representing approximately 90% or more of the total amount of the stereoisomers obtained. In even more preferred embodiments, the amount of the preferred stereoisomer is at least 95%, even more preferably at least about 97% of the total amount of phenylseleno blocked lactone produced.

    专利号:US-7094805-B2
    优先权日:2001-12-14
    标 题 :Total synthesis of merrilactone A
    发明人:DANISHEFSKY SAMUEL J; BIRMAN VLADIMIR B
    权利人:UNIV COLUMBIA
    摘要:This invention provides a total synthesis of Merrillactone and Merrilactone analogues for use as neurotrophic agents in the treatment of neurodegenerative diseases. The invention also provides intermediates for use in the synthesis of Merrilactone and its analogues.

    专利号:US-12234203-B2
    优先权日:2020-03-12
    标 题:Process for the synthesis of cannabidiol and intermediates thereof
    发明人:ANAND RADHIKA; SHARMA SUMIT; SINGH CHAM PANKAJ; GANNEDI VEERANJANEYULU; KUMAR MUKESH; PRATAP SINGH VARUN; PRAKASH RAHUL VISHAV; ASREY VISHWAKARMA RAM; PAL SINGH PARVINDER
    权利人:COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF T; COUNCIL OF SCIENT AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN OF S
    摘要:The present invention relates to process for the preparation of cannabidiol (A) from the coupling of (D) and (E) through the intermediates (C) and (D) starting from compound (B). The invention further relates to the novel compounds (B), (C), (D) and (E) and reagents used in this process. More specifically, this invention provides the manufacturing of Cannabidiol (A) in milligram to gram or kilogram scale.

    专利号:EP-1274680-B1
    优先权日:2000-04-18
    标 题 :Synthesis intermediate products for producing vitamin d derivatives
    发明人:STEINMEYER ANDREAS; BOIDOL WERNER; ZORN LUDWIG
    权利人:SCHERING AG
    摘要:The invention relates to a new synthesis intermediate product of formula I its microbiological production and use for synthesis of vitamin D derivatives.

    专利号:US-10899878-B2
    优先权日:2017-04-06
    标 题:Phosphorus-containing caprolactone monomers for synthesis of flame retardant polycaprolactones
    发明人:CAMPBELL ERIC J; CZAPLEWSKI SARAH K; KOBILKA BRANDON M; WERTZ JASON T
    权利人:IBM
    摘要:A process of forming a flame retardant monomer includes forming a hydroxyl-functionalized caprolactone molecule, and reacting the hydroxyl-functionalized with a phosphorus-containing flame retardant molecule to form a flame retardant-functionalized caprolactone monomer. A flame retardant monomer includes at least one moiety derived from a hydroxyl-functionalized caprolactone molecule and at least one phosphorus-containing flame retardant moiety. A flame retardant polymer includes at least two flame retardant monomer repeat units, each flame retardant monomer repeat unit including at least one moiety derived from a hydroxyl-functionalized caprolactone molecule and at least one phosphorus-containing flame retardant moiety.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Nahm Garrett, M.; Johnson, J. S., Science of Synthesis Knowledge Updates, (2012) 2, 58.
    摘要:Schatz, J.; Seßler, M., Science of Synthesis Knowledge Updates, (2010) 1, 86.
    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2014) 4, 148.
    摘要:Nieto, C. T.; Eames, J.; Garrido, N. M., Science of Synthesis Knowledge Updates, (2019) 1, 117.
    摘要:Stanforth, S. P., Science of Synthesis Knowledge Updates, (2014) 3, 101.
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