CAS: 3411-48-1; Tri(Naphthalen-1-yl)Phosphine

上下游产品

1-Bromonaphthalene dimethyl sulfoxidetri(1-naphthyl)phosphine sulfide

1-溴代萘置于正丁基锂,三氯化磷体系中,用 四氢呋喃,正己烷 作为反应溶剂,化学反应 5.17H,以32%的收率获得产物三(1-萘基)膦
参考文献:萘基单齿大分子膦和亚磷酸酯配体的铑配合物催化乙酸乙烯酯的区域选择性加氢甲酰化
标题:萘基单齿大分子膦和亚磷酸酯配体的铑配合物催化乙酸乙烯酯的区域选择性加氢甲酰化
摘要:乙酸乙烯酯的加氢甲酰化反应是使用萘基单齿大膦和亚磷酸酯配体的铑配合物进行的.所有基于萘基的配体都有助于形成所需的支链醛.使用大体积的亚磷酸酯配体观测到高周转频率,对支链醛具有非常好的区域选择性和对醛的高选择性.co和h 2分压的影响准确地考察了乙酸乙烯酯的浓度,搅拌速率和溶剂对rh /亚磷酸亚砜催化乙酸乙烯酯加氢甲酰化反应的影响,以提高催化活性和选择性.与常规有机溶剂相比,在有机碳酸盐("绿色"溶剂)中,特别是在碳酸亚丙酯(pc)中,观测到了对活性和选择性的重大影响.pc /催化剂体系可以循环使用而不会显着降低活性和选择性.
DOI:10.1016/j.Apcata.2012.01.027

专利信息

专利号:US-2017014805-A1
优先权日:2014-04-22
标 题 :Method for the synthesis of supported gold (au) nanoparticles for epoxidation reactions
发明人：AL-HAZMI MOHAMMED H
权利人:SABIC GLOBAL TECHNOLOGIES BV
摘要:Processes for preparing supported gold nanoparticle catalysts are provided. In an exemplary embodiment, the process includes adding a solution of a phosphorus compound to a solution of chloro (dimethyl sulfide) gold (I) to obtain a solution of chloro (phosphorus compound) gold (I) complex, adding the solution of chloro (phosphorus compound) gold (I) complex to a solution of silver nitrate to obtain a solution of nitro (phosphorus compound) gold (I) complex, applying the solution of nitro (phosphorus compound) gold (I) complex to a metal hydroxide support, drying the metal hydroxide support; and calcining the dried metal hydroxide support to form the supported gold nanoparticle catalyst. Supported gold nanoparticle catalysts prepared by the process and processes for oxidizing ethylene to ethylene oxide in the presence of the supported gold nanoparticle catalysts are also provided.

专利号:US-2025082793-A1
优先权日:2021-11-09
标 题 :Macrocyclic compounds and methods of making the same
发明人：CLEATOR EDWARD; MATON WILLIAM MARC; SALTER RHYS
权利人:JANSSEN BIOTECH INC
摘要:The present invention is directed to the preparation of key intermediates and synthesis of compounds (macrocyclic compounds) and pharmaceutically acceptable salts thereof, immunoconjugates, radioimmunoconjugates thereof, pharmaceutical compositions containing said compounds and immunoconjugates, radioimmunoconjugates thereof.

专利号:US-7563877-B2
优先权日:2006-03-02
标题 :Processes for the preparation of 0-(2-aminobenzo[d]oxazol-5-yl)methyl hydroxylamine for the synthesis of 6,11-bicyclic erythromycin derivative EDP-182
发明人：XU GUOYOU; GAI YONGHUA; WANG GUOQIANG; OR YAT SUN; WANG ZHE
权利人:ENANTA PHARM INC
摘要:The present invention relates to processes and intermediates for the preparation of 6-11 bicyclic erythromycin derivative known as EDP-182 (IX-a). In particular, the present invention relates to processes and intermediates for the preparation of O-(2-aminobenzo[d]oxazol-5-yl)methyl hydroxylamine:

专利号:US-12187735-B2
优先权日:2018-09-17
标 题:Matter of composition, synthesis, formulation and application of FL118 platform positions 7 and 9-derived analogues for treatment of human disease
发明人：LING XIANG; LI QINGYONG; LI FENGZHI
权利人:CANGET BIOTEKPHARMA LLC
摘要:Described herein, are the chemical synthesis, matter of compositions, formulation, function, methods and uses of the FL118 platform Positions 7 and/or 9-derived analogues for treating cancer or other human diseases. Compounds derived from chemical modifications of the FL118 platform are employed alone or in combination with other anti-cancer agents to preclude, eliminate or reverse cancer phenotypes. This invention intends to realize unique personalized cancer treatment (personalized precision medicine) through application of a series of structural relevant individual FL118 platform-derived analogues, which target multiple cellular human disease-relevant proteins and their signaling pathways.

专利号:US-2025092058-A1
优先权日:2018-09-17
标 题 :Matter of composition, synthesis, formulation and application of fl 118 platform positions 7 and 9-derived analogues for treatment of human disease
发明人：LING XIANG; LI QINGYONG; LI FENGZHI
权利人:CANGET BIOTEKPHARMA LLC
摘要:Described herein, are the chemical synthesis, compounds, methods and uses of the fluoroaryl-substituted derivatives at the FL118 position 7, which target multiple cellular human disease-relevant proteins and their signaling pathways.

专利号:US-7214807-B2
优先权日:2000-02-25
标 题 :Method for the preparation of fluticasone and related 17β-carbothioic esters using a novel carbothioic acid synthesis and novel purification methods
发明人：BARKALOW JUFANG; CHAMBERLIN STEVEN A; COOPER ARTHUR J; HOSSAIN AZAD; HUFNAGEL JOHN J; LANGRIDGE DENTON
权利人:ABBOTT LAB
摘要:This invention discloses a novel method for the conversion of carboxylic acids to carbothioic acids and application of the method to the preparation of androstane carbothiolates, such as fluticasone propionate, which avoids column chromatography.