CAS: 338454-02-7; Methyl 3,5-Dihydroxy-4-Iodobenzoate

上下游产品

CAS号67-56-1 甲醇 | CAS号76447-13-7 3,5-dihydroxy-4... | CAS号2150-44-9 3,5-二羟基苯甲酸甲酯 | CAS号314725-17-2 4-羟基-2-甲基苯并呋喃-6-羧酸甲酯

📜3,5-二羟基苯甲酸甲酯置于n-碘代丁二酰亚胺体系中,用 氘代甲醇-D 用作溶剂,化学反应 16.0H,以91%的收率获得3,5-二羟基-4-碘苯甲酸甲酯
参考文献:通过斯蒂尔偶联反应全合成异赫里烯酮 J.
标题:通过斯蒂尔偶联反应全合成异赫里烯酮 J.
摘要:首次报道了异赫里油酮 J 的全合成.这种合成策略的主要特征是构建异苯并呋喃酮单元的 Friedel-Crafts 反应和形成 C5-C1' 键的 Pd 催化的 Stille 偶联反应,生成天然产物及其异构体之一,分八步获得 6.0% 的总收率.该策略为合成具有挑战性的异苯并呋喃酮和异吲哚啉酮类衍生物奠定了基础.
Doi:10.1021/acs.Jnatprod.9B01251

专利信息

专利号:US-9957291-B2
优先权日:2013-08-05
标题 :Protected fluorescent reagent compounds
发明人：SEBO LUBOMIR; HANES JEREMIAH; SHEN GENE; BROGLEY LOUIS; YUE STEPHEN; ZHENG FRANK; LAPIN YURI; LYLE JOHN; OSUNA HONEY; FEDOROV ANDREI
权利人:PACIFIC BIOSCIENCES CALIFORNIA INC
摘要:Protected fluorescent reagent compounds and their methods of synthesis are provided. The compounds are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The compounds contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements.

专利号:US-10787573-B2
优先权日:2015-02-04
标 题:Multimeric protected fluorescent reagents
发明人：ZHENG FRANK; HANES JEREMIAH; SHEN GENE; BROGLEY LOUIS; YUE STEPHEN; LAPIN YURI; LYLE JOHN; OSUNA HONEY; FEDOROV ANDREI; SEBO LUBOMIR
权利人:PACIFIC BIOSCIENCES CALIFORNIA INC
摘要:Multimeric protected fluorescent reagents and their methods of synthesis are provided. The reagents are useful in various fluorescence-based analytical methods, including the analysis of highly multiplexed optical reactions in large numbers at high densities, such as single molecule real time nucleic acid sequencing reactions. The reagents contain fluorescent dye elements, that allow the compounds to be detected with high sensitivity at desirable wavelengths, binding elements, that allow the compounds to be recognized specifically by target biomolecules, and protective shield elements, that decrease undesirable contacts between the fluorescent dye elements and the bound target biomolecules and that therefore decrease photodamage of the bound target biomolecules by the fluorescent dye elements. The reagents also contain coupling elements connect monomeric compounds into multimeric forms, thereby increasing brightness.

专利号:CN-110669031-A
优先权日:2019-11-26
标题 :The total synthesis method of natural product isohericin J

专利号:RU-2733750-C2
优先权日:2015-09-02
标题:Derivatives of carboxy-substituted (hetero)aromatic rings, method of synthesis and use thereof

专利号:CN-110669031-B
优先权日:2019-11-26
标 题:Total synthesis method of natural product isoperidone J