CAS: 23973-51-5; S-Allyl Ethanethioate

上下游产品

CAS号107-05-1 氯丙烯 | CAS号507-09-5 硫代乙酸 | CAS号107-18-6 烯丙醇 | CAS号106-95-6 烯丙基溴 | CAS号34832-35-4 SODIUM THIOLACETATE | CAS号10387-40-3 硫代乙酸钾 | CAS号16621-54-8 thioacetic acid... | CAS号870-23-5 烯丙硫醇 | CAS号108-24-7 乙酸酐 | CAS号870-23-5 烯丙硫醇 | CAS号14418-84-9 2-丙烯-1-磺酰氯

📜甲烷磺酸烯丙酯置于potassium Carbonate体系中,用 水 用作溶剂,化学反应 2.0H,以92%的收率获得硫代乙酸烯丙酯
参考文献:在水中高效合成有机硫代乙酸酯
标题:在水中高效合成有机硫代乙酸酯
摘要:硫代乙酸盐作为硫醇的前体是合成其他有机硫化合物的有趣起点.本文中,我们提出一种简单,有效和快速的方法,以水用作溶剂获得有机硫代乙酸盐.考虑到过去几十年来对环境友好的合成方法的高度重视,我们证明了硫代乙酸根阴离子作为亲核试剂在水性介质中进行亲核取代反应的作用和强度.使用碳酸钾作为安全和温和的碱,在ph控制下进行反应以防止甲磺酸酯原料分解.简单的后处理即可获得具有优异收率和可接受纯度的产品.
Doi:10.1039/c8Ob01896K

专利信息

专利号:US-2023312827-A1
优先权日:2022-04-04
标 题 :Synthesis of novel poly(ester urea)s for drug delivery
发明人：OLSEN BRADLEY D; SUREKA HURSH VARDHAN; FRANSEN KATHARINA
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Disclosed are poly(ester urea)s containing two or more units containing two amino acid monomers linked by a linker. At least two units of the poly(ester urea)s are covalently bonded via a urea bond. Suitable amino acid monomers are lysine, arginine, aspartic acid, phenylalanine, or a side chain protected derivative thereof, and suitable linkers are selected from a 1,4-butane diol group, a 1,6-hexane diol group, diethylene glycol group, a triethylene glycol group, or an N-methyl diethanolamine group. The poly(ester urea)s are used to form polyplexes for the improved complexation and delivery of drugs to a subject in need thereof.

专利号:WO-2023196299-A1
优先权日:2022-04-04
标 题:Synthesis of novel poly(ester urea)s for drug delivery

专利号:US-12378584-B2
优先权日:2018-06-13
标 题 :Methionine analogue synthesis
发明人：WILTSCHI BIRGIT; FLADISCHER PATRIK; OFFNER-MARKO LISA-RAMONA; HECKENBICHLER KATHRIN; BREINBAUER ROLF
权利人:ENGENES BIOTECH GMBH
摘要:The present invention relates to a method for preparing a methionine analogue, comprising contacting a host cell with L-homoserine and one or more nucleophiles and cultivating said host cell and said one or more nucleophiles of (a) in a fermentation broth to produce said methionine analogue, wherein said host cell encodes and stably expresses a L-homoserine-O-acetyl-transferase (HSAT) and an O-acetyl-L-homoserine sulfhydrylase (OAHS). The present invention also relates to host cells encoding and expressing such HSAT and OAHS, as well as uses thereof for producing a methionine analogue.