CAS: 21312-10-7; N-(4-(N-(5-Methylisoxazol-3-yl)Sulfamoyl)Phenyl)Acetamide

该化合物是一种含有含有异氧新诺明环和乙酰胺组的分子结构的磺酰胺衍生物,该化合物作为制药合成的中间体具有潜力,特别是因其磺酰胺混合物而开发抗微生物剂或抗炎剂方面的潜力,其结构特征,包括5-甲基异氧新诺醇-3-yl组,可能有助于增强代谢稳定性和目标特性.该化合物定义明确的化学特性使其适合于医学研究应用,而精确的分子修改至关重要.在标准条件下,其纯性和稳定性进一步支持其在受控合成工艺中的用途.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

5-methylisoxazol-3-ylamine p-acetylaminobenzenesulfonyl chloride sulfamethoxazole acetyl chloride N-(4-acetylamino-benzenesulfonyl)-N-(5-methyl-isoxazol-3-yl)-acetamideN-(4-acetylamino-benzenesulfonyl)-N-(5-methyl-isoxazol-3-yl)-acetamide SMZ chloride 3,4-dichloro-N-(4-(N-(5-methylisoxazol-3-yl)sulfamoyl)phenyl)benzamide 4-(3-benzylthioureido)-N-(5-methylisoxazol-3-yl)benzenesulfonamide

合成工艺路线路线简述

    📜4-硝基磺胺甲恶唑置于铂 氢气体系中,用 吡啶,乙醇 用作溶剂,化学反应 0.5H,反应生成醋磺胺甲噁唑
    参考文献:Fujimoto,M.; Okabe,K.,Chemical And Pharmaceutical Bulletin,1962,Vol. 10,P. 572-575
    标题:Fujimoto,M.; Okabe,K.,Chemical And Pharmaceutical Bulletin,1962,Vol. 10,P. 572-575

    海关参考信息

    专利信息


    专利号:US-5338686-A
    优先权日:1992-04-29
    标 题:Method for measuring in vivo synthesis of biopolymers
    发明人:HELLERSTEIN MARC K
    权利人:HELLERSTEIN MARC K
    摘要:A method for determining the mass isotope enrichment of a subunit from which a biopolymer is formed, and the rates of synthesis and decay of the biopolymer. The mass isotope enrichment of the subunit is determined by comparing the mass isotopomer distribution of the biopolymer after administration of a mass isotopically labeled subunit, with the expected frequencies of the different mass isotopomers produced from a given subunit mass isotope enrichment. To determine the synthesis rate of the biopolymer, the expected frequency of a selected biopolymer mass isotopomer, calculated from the subunit isotope enrichment, is compared with the actual frequency of that biopolymer mass isotopomer. To determine biopolymer decay, the decay rate of high mass isotopomers of the biopolymer is determined.

    专利号:CN-110441447-B
    优先权日:2019-09-11
    标题:Deuterated sulfamethoxazole-d4Method of synthesis of

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1021/ac0496603
    摘要:Göbel A, McArdell CS, Suter MJ, Giger W. Trace determination of macrolide and sulfonamide antimicrobials, a human sulfonamide metabolite, and trimethoprim in wastewater using liquid chromatography coupled to electrospray tandem mass spectrometry. Anal Chem. 2004 Aug 15;76(16):4756–64. doi: 10.1021/ac0496603.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知