CAS: 16369-14-5; 2-Aminopentan-1-Ol

该化合物是一种有机化合物,其特征为:氨基组(-NH2)和与五碳烷链相连的羟基组(-OH),该化合物被归类为氨基酒精,具有独特的特性,如参与氢结合的能力,提高其在水中的溶性,其物理和化学特性,包括沸点和密度,受到现有分子结构和功能组的影响,使其成为有机化学的多种化合物.

结构式图片

相似化合物

22724-81-8 2025376-01-4 2013-12-9

欧盟法规

C&L通报

上下游产品

2-nitro-pentan-1-ol D,L-valine 2-aminopentanoic acid ethyl 2-aminopentanoateNicotinic acid 2-[(pyridine-3-carbonyl)-amino]-pentyl ester N-(1-Hydroxymethyl-butyl)-butyramide (+/-)-2-(acetylamino)pentyl acetate 2-acetylaminopentan-1-ol

合成工艺路线路线简述

  • 56-86-0 = 16369-14-5 + 498-63-5 + 63493-28-7 + 62400-75-3 + 98-79-3 + 40217-11-6 + 927-55-9 + 21926-01-2 + 533-88-0
    反应条件:1.1 Reagents: Hydrogen,Phosphoric Acid Catalysts: Rhodium,Molybdenum Oxide Solvents: Water; 6 H,Ph 1.8,70 Bar,100 °C
    标题:Rh-Catalyzed Hydrogenation Of Amino Acids To Biobased Amino Alcohols: Tackling Challenging Substrates And Application To Protein Hydrolysates
    作者:Vandekerkhove,Annelies; Claes,Laurens; De Schouwer,Free; Van Goethem,Cedric; Vankelecom,Ivo F. J.; Et Al
    参考文献:Acs Sustainable Chemistry & Engineering 日期:2018 卷标:6(7) 页码:9218-9228

海关参考信息

专利信息


专利号:US-8877977-B2
优先权日:2011-11-25
标题 :Synthesis of polyalkylenepolyamines having a low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen
发明人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO
权利人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO; BASF SE
摘要:Process for the preparation of polyalkylenepolyamines by homogeneously catalyzed alcohol amination, in which aliphatic amino alcohols are reacted with one another or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols with the elimination of water in the presence of a homogeneous catalyst and in the presence of hydrogen gas. Polyalkylenepolyamines obtainable by such processes and polyalkylenepolyamines comprising hydroxy groups, secondary amines or tertiary amines. Uses of such polyalkylenepolyamines as adhesion promoters for printing inks, adhesion promoters in composite films, cohesion promoters for adhesives, crosslinkers/curing agents for resins, primers for paints, wet-adhesion promoters for emulsion paints, complexing agents and flocculating agents, penetration assistants in wood preservation, corrosion inhibitors, immobilizing agents for proteins and enzymes.

专利号:WO-2013076053-A1
优先权日:2011-11-25
标题:Synthesis of polyalkylene polyamines with low color index by homogeneously catalyzed alcohol amination in the presence of hydrogen
发明人:STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO
权利人:BASF SE; STRAUTMANN JULIA; SCHAUB THOMAS; HUEFFER STEPHAN; MAAS STEFFEN; PACIELLO ROCCO
摘要:The invention relates to a method for the production of polyalkylene polyamines by homogeneously catalyzed alcohol amination, wherein aliphatic alkanolamines are reacted with each other or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols in the presence of a homogeneous catalyst while eliminating water and in the presence of hydrogen gas. The invention further relates to polyalkylene polyamines, which can be obtained by said methods, and to polyalkylene polyamines which contain hydroxyl groups, secondary amines or tertiary amines. The invention finally relates to uses of said polyalkylene polyamines as adhesion promoters in inks, adhesion promoters in composite films, cohesion promoters in adhesives, cross-linkers/hardeners for resins, primers for paints, wet adhesion promoters for dispersion paints, complexing agents and flocculants, penetration auxiliaries for use in wood preservation, corrosion inhibitors, and immobilization agents of proteins and enzymes.

专利号:WO-2013136265-A1
优先权日:2012-03-13
标 题:Synthesis of an intermediate of an antiviral compound
发明人:ATTOLINO EMANUELE; BOVE ALESSIO; BRUNOLDI ENRICO; ALLEGRINI PIETRO
权利人:DIPHARMA FRANCIS SRL
摘要:Process for the preparation of a cyclopropylamide compound which is useful as a structural unit in a process for the preparation of a viral protease inhibitor.

专利号:US-7344868-B2
优先权日:2003-06-03
标题:Method for synthesizing ceramide-type compounds
发明人:LASSALLE LAURENT; YVERGNAUX FLORENT
权利人:LASSALLE LAURENT; YVERGNAUX FLORENT
摘要:The invention relates to the fields of fatty substance chemistry, specifically of the ceramide-type compound synthesis. The invention resides substantially in the synthesis of ceramide-type compounds. Specifically, the aim of the invention is a new enzymatic synthesis method, comprising at least one amidification step and one esterification step, achieved through lipases, among fatty acids and/or esters thereof and amino alcohols. The resulting ceramide-type compounds can be used as cosmetic and/or pharmaceutical compositions, in particular as dermatological compositions in conjunction or in admixture with one or more suitable cosmetic and/or pharmaceutical excipients or carriers. The method has an interest particularly in the synthesis of active compounds useful in the fields of cosmetology and/or pharmacology and specifically of dermatology.

专利号:EP-0946499-B1
优先权日:1996-11-22
标 题 :N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人:WU JING; TUNG JAY S; NISSEN JEFFREY S; MABRY THOMAS E; LATIMER LEE H; EID CLARK NORMAN; AUDIA JAMES E
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions. Said compounds are represented by formula (I), wherein R<1> is selected from the group consisting of: a) alkyl, alkenyl, alkaryl, alkcycloalkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl and heterocyclic; b) a substituted phenyl group of formula (II), wherein R is alkylene of from 1 to 8 carbon atoms, m is an integer equal to 0 or 1, and c) 1- or 2-naphthyl substituted at the 5, 6, 7 and/or 8 positions, R<2> is selected from the group consisting of hydrogen, alkyl of from 1 to 4 carbon atoms, alkylalkoxy of from 1 to 4 carbon atoms, alkylthioalkoxy of from 1 to 4 carbon atoms; and R<3> and R<3'> are independently selected from the group consisting of: (a) hydrogen, (b) alkyl, (c) -(R<7>)n(W)p, wherein R<7> is an alkylene group, W is selected from the group consisting of (i) formula (A); (ii) heteroaryl; and (iii) N-heterocyclic, and n is an integer equal to 0 or 1, and p is an integer equal to 1 to 3; (d) -CH( phi )CH2C(O)O-Q where Q is selected from the group consisting of alkyl, aryl, heteroaryl and heterocyclic; X' is hydrogen, hydroxy or fluoro; X'' is hydrogen, hydroxy or fluoro, or X' and X'' together form an oxo group, Z is selected from the group consisting of a bond covalently linking R<1> to -CX'X''-, oxygen and sulfur.

专利号:US-6262302-B1
优先权日:1996-11-22
标题:N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人:WU JING; TUNG JAY S; NISSEN JEFFREY S; MABRY THOMAS E; LATIMER LEE H; EID CLARK N; AUDIA JAMES E
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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合成参考文献


参考文献:10.1007/s11030-005-9009-x
摘要:Roy DR, Sarkar U, Chattaraj PK, Mitra A, Padmanabhan J, Parthasarathi R, Subramanian V, Van Damme S, Bultinck P. Analyzing toxicity through electrophilicity. Mol Divers. 2006 May;10(2):119–31. doi: 10.1007/s11030-005-9009-x.
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