专利号:US-7056348-B2 优先权日:2001-04-19 标题:5-aryl-1,3,3-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibers 发明人:SAUTER GUIDO; BRAUN HANS-JUERGEN; REICHLIN NADIA 权利人:WELLA AG 摘要:A method for the synthesis of 5-aryl-1,3,3,-trimethyl-2-methylene-indoline derivatives of Formula (I) or its salts of Formula (Ia) wherein 1 mole of a 5-aryl-2,3,3-trimethyl-3H-indole derivative of Formula (VII) is reacted for 1 to 44 hours at a temperature of 20° to 180° C. in an apolar, aprotic or polar, protic or polar aprotic solvent with 1 to 50 moles of a compound of Formula R1-A; new compounds of Formulas (I)/(Ia) and (V), obtainable by this method as well as an agent containing at least one compound of Formula (I)/(Ia) and a carbonyl/imine compound for dyeing keratinic fibers and a method for temporarily dyeing keratin fibers, for which the keratin fiber is dyed with the aforementioned agent and the dyeing, so obtained, is removed again at any later time by a sulfite preparation.
专利号:EP-1921076-A1 优先权日:2002-10-11 标题:systhesis of procyanidin B2 发明人:CASTILLO GERARDO M; NGUYEN BETH P; CHOI PAULA Y; LARSEN LESLEY; LORIMER STEPHEN D; SNOW ALAN D 权利人:PROTEOTECH INC 摘要:Methods for the synthesis of procyanidin B2 are disclosed. The synthetic methods utilize epicatechin as a starting material and produce procyanidin BZ in high yields.
专利号:US-7449617-B2 优先权日:2004-01-05 标题 :Plants with elevated levels of gallic acid/polyphenol oxidase and methods of generating such plants 发明人:DANDEKAR ABHAYA; MUIR RYANN M 权利人:UNIV CALIFORNIA 摘要:Gallic acid inhibits the synthesis by A. flavus of aflatoxin, a toxic carcinogen that can contaminate crops such as corn, peanuts and walnuts rendering them inedible. The present invention takes advantage of this inhibition to provide various methods and compositions useful for protecting crops from contamination. Gallic acid is also an intermediate in the production of hydrolyzable tannins, which may sequester protein in the rumen, prevent ammonia formation, and allow protein to be more efficiently absorbed in the post-ruminant digestive system. A second gene, polyphenol oxidase (PPO), also from walnut, may act to help sequester protein during ensiling, also protecting and improving nutritional value. The present invention includes non-naturally occurring plants that contain elevated levels of PPO or gallic acid as well as various methods of generating such plants. The present invention further provides methods of application of gallic acid to prevent contamination. In addition, the present invention provides certain genes and proteins that are be useful in making the non-naturally occurring plants.
专利号:US-2003100775-A1 优先权日:2000-09-05 标 题 :Synthesis of 4alpha-arylepicatechins
专利号:US-7875302-B2 优先权日:2004-12-14 标题:Methods of using grape seed extract to stimulate tyrosinase gene expression 发明人:DUVEL LANE A; RUA DIEGO; MISSLER STEPHEN R; FAST DAVID J; CHANDRA AMITABH 权利人:ACCESS BUSINESS GROUP INT LLC 摘要:The present invention relates to methods of increasing tyrosinase synthesis, expression, or activity in a cell comprising administering at least one grape seed extract to the cell. The grape seed extract may be obtained by any extraction process including solvent sequential fractionation and supercritical fluid extraction.
专利号:US-2007173543-A1 优先权日:2006-01-26 标 题:Synthesis of polycyclic procyanidins
参考标题:A Facile Microwave And Sncl2 Synthesis Of 2,3-Dihydroquinazolin-4(1H)-Ones 作者:Nicholas S. O'Brien,Adam Mccluskey 摘要:An Elegantly Simple, Facile, And Robust Approach To A Scaffold Of Biological Importance, 2,3-Dihydroquinazolin-4(1H)-Ones, Is Reported. A Catalytic 1 % Sncl2/microwave-Mediated Approach Afforded Access To Pure Material, Collected By Cooling And Filtration After 20-Min Microwave Irradiation At 120°C. A Total Of 41 Analogues Were Prepared In Isolated Yields Of 17-99 %. This Process Was Highly Tolerant
合成参考文献
参考文献:10.4103/0972-124x.82258 摘要:Venkateswara B, Sirisha K, Chava VK. Green tea extract for periodontal health. J Indian Soc Periodontol. 2011 Jan;15(1):18–22.