CAS: 2894-51-1; (2-Aminophenyl)(4-Chlorophenyl)Methanone

上下游产品

CAS号106-39-8 对氯溴苯 | CAS号133776-41-7 2-氨基-N-甲氧基-N-甲基苯甲酰胺 | CAS号623-03-0 对氯苯腈 | CAS号122-01-0 4-氯苯甲酰氯 | CAS号118-48-9 靛红酸酐 | CAS号6311-23-5 2-{[(4-甲基苯基)磺酰基... | CAS号5100-23-2 Benzoyl chlorid... | CAS号108-90-7 氯苯 | CAS号20953-66-6 9-(4-chlorophen... | CAS号2894-52-2 5-(4-chlorophen... | CAS号7254-06-0 3-氯-9H-芴-9-酮 | CAS号78281-73-9 AHR-10037 | CAS号65246-99-3 (2-amino-5-brom... | CAS号827576-99-8 N-[4-[[2-(4-chl... | CAS号60252-95-1 9-(4-chlorophen... | CAS号61085-31-2 7-(4-chlorobenz... | CAS号61112-01-4 7-(4-chlorobenz...

2-(Toluene-4-Sulfonylamino)-Benzoyl Chloride置于三氯化铝,硫酸体系中,化学反应 4.25H,反应生成2-氨基-4'-氯二苯甲酮
参考文献:Synthesis And Biological Evaluation Of Substituted 2-Sulfonyl-Phenyl-3-Phenyl-Indoles: A New Series Of Selective Cox-2 Inhibitors
标题:Synthesis And Biological Evaluation Of Substituted 2-Sulfonyl-Phenyl-3-Phenyl-Indoles: A New Series Of Selective Cox-2 Inhibitors
摘要:A New Series Of Substituted 2-Sulfonyphenyl-3-Phenyl-Indole Derivatives Were Synthesized And Evaluated For Their Ability To Inhibit Cox-2 And Cox-Lenzymes. Most Of The Compounds Synthesized Were Found To Be Highly Potent And Selective Inhibitors Of Cox-2. This Work Led To The Discovery Of 2-Aminosulfonylphenyl-3-Phenyl-Indole 5A Which Possesses Higher Activity And Selectivity For Cox-2 Than Celecoxib Both In Vitro And In Vivo. (C) 2003 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/s0968-0896(03)00046-4

专利信息

专利号:RU-2071962-C1
优先权日:1987-12-18
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优先权日:2018-12-03
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优先权日:2023-09-18
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优先权日:2019-09-30
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