CAS: 22255-22-7; (E)-1,3-Dimethoxy-5-(4-Methoxystyryl)Benzene

上下游产品

CAS号153139-20-9 (+/-)-1-(3,5-di... | CAS号24131-30-4 (3,5-DIMETHOXYB... | CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号667458-79-9 3,5-dimethoxybe... | CAS号7311-34-4 3.5-二甲氧基苯甲醛 | CAS号1145-93-3 (4-甲氧基苄基)磷酸二乙酯 | CAS号863560-56-9 [3,5-bis(triflu... | CAS号877-88-3 3,5-二甲氧基苄溴 | CAS号100-66-3 苯甲醚 | CAS号824-94-2 4-甲氧基苄氯 | CAS号501-36-0 白藜芦醇 | CAS号63366-84-7 2,4,6-trimethox...

1,3-二甲氧基-5-[2-(4-甲氧基苯基)乙炔基]苯置于nickel(II) Iodide,1,1'-双(二苯基膦)二茂铁,氢气体系中,用 1,4-二氧六环 用作溶剂,20.0~100.0 °C,2.0 Mpa 条件下,反应 18.03H,以79%的收率获得3,4',5-三甲氧基-反-二苯代乙烯
参考文献:一种实现电子选择性炔烃半加氢的简单镍催化剂
标题:一种实现电子选择性炔烃半加氢的简单镍催化剂
摘要:立体选择性炔烃半氢化是制备烯烃的有吸引力的方法,烯烃是合成的关键组成部分.对于最具原子经济性的还原剂二氢(h 2 ),仅公开了少数用于具有挑战性的e-选择性炔烃半氢化的催化剂,每种催化剂都具有独特的底物范围特征.在这里,我们表明,市售的镍催化剂促进了多种取代内炔的e-选择性炔烃半氢化.这产生了一个简单且广泛适用的整体方案,用于使用 H 2立体选择性地访问e-烯烃,这可以作为通用的合成方法.
Doi:10.1002/chem.201903850

专利信息

专利号:US-6552213-B1
优先权日:2002-05-10
标 题:Stereoselective route to produce tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, an intermediate in the synthesis of trans-resveratrol
发明人：DESHPANDE PANDURANG BALWANT; SENTHILKUMAR UDAYAMPALAYAM PAL; ANDREW GNANAPRAKASAM
权利人:ORCHID CHEMICALS & PHARM LTD
摘要:The present invention relates to a new stereoselective method for the preparation of tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene derivative of the formula (I) which is a key intermediate in the synthesis of trans-resveratrol (I, R2=R2=R3=H). The invention also provides a method for the exclusive synthesis of trans-isomer of compounds of formula (I) without any contamination of cis-isomer.

专利号:US-8399714-B2
优先权日:2007-10-03
标题 :Process for the synthesis of polyhydroxystilbene compounds
发明人：VALLEJOS JEAN-CLAUDE; SCHOUTEETEN ALAIN; WILHELM DIDIER
权利人:VALLEJOS JEAN-CLAUDE; SCHOUTEETEN ALAIN; WILHELM DIDIER; CLARIANT SPECIALITY FINE CHEMICALS FRANCE
摘要:The invention relates to a process for the synthesis of stilbene derivatives of formula (I)-(E) or (I)-(Z) n nin which R represents hydrogen or an OH group,n nby deprotection in the presence of an aluminum halide and of a tertiary amine of a compound of formula (II)-(E) or (II)-(Z)n n nin which A represents hydrogen or an OR′ 1 group, and R 1 , R 2 , R 3 and R′ 1 independently represent an alkyl or aralkyl group.

专利号:US-7253324-B1
优先权日:2007-01-23
标 题:Process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkylethers
发明人：MAJEED MUHAMMED; THOMAS SAMUEL MANOHARAN; NAGABHUSHANAM KALYANAM; BALAKRISHNAN SIVAPRAKASH KURUM; PRAKASH SUBBALAKSHMI
权利人:SAMI LABS LTD
摘要:Alkoxy aromatic compounds are conveniently dealkylated to the corresponding phenolic compounds by treatment with aluminum chloride/N,N-dimethyl aniline complex. Aromatic poly O-demethylation is a unique feature of this invention. This process is applicable to the manufacture of polyphenols such as Resveratrol, Oxyresveratrol, Gnetol.

专利号:US-7705188-B2
优先权日:2002-04-10
标 题:Structural modification of resveratrol: sodium resverastatin phosphate
发明人：PETTIT GEORGE R; GREALISH MATTHEW P
权利人:UNIV ARIZONA
摘要:Described herein are novel compounds having antineoplastic and antimicrobial activity, obtained via structural modifications of resveratrol and combretastatin A-4, methods for synthesis of these compounds, and their use in pharmaceutical composition and for use in the treatment of mammals having cancer. Examples of the novel compounds are: (Z)- and (E)-3,4′,5-trimethoxystilbene (4a, 4b); (Z)- and (E)-3,5-dimethoxy-4′-hydroxystilbene (14c, 14d); (Z)- and (E)-3-hydroxy-4′,5-dimethoxystilbene (14g, 14h); (Z)- and (E)-3,5-dihydroxy-4′-methoxy-stilbene (14k, 14l); sodium resverastatin dibenzyl phosphate ((Z)-3,5-dimethoxy-4-[O-bis(benzyl)phosphoryl]-stilbene) (14m); and sodium resverastatin phosphate (14n).

专利号:WO-2008091379-A1
优先权日:2007-01-23
标题 :A process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkyllethers

专利号:WO-2009043761-A1
优先权日:2007-10-03
标题:Process for the synthesis of polyhydroxystilbene compounds