CAS: 2217-44-9; Disodium 2-[(3,5-Diiodo-4-Oxidophenyl)(3,5-Diiodo-4-Oxo-2,5-Cyclo Hexadien-1-Ylidene)Methyl]Benzoate

专利信息

专利号:US-12410410-B2
优先权日:2015-02-10
标题 :Ketoreductase polypeptides for the synthesis of chiral compounds
发明人：ALVIZO OSCAR; AGARD NICHOLAS J; XIE XINKAI; ENTWISTLE DAVID; KOSJEK BIRGIT
权利人:CODEXIS INC
摘要:The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.

专利号:US-9624478-B2
优先权日:2011-09-08
标题:Biocatalysts and methods for the synthesis of substituted lactams
发明人：CABIROL FABIEN LOUIS; CHEN HAIBIN; GOHEL ANUPAM; SALIM PAULINA ELENA; SMITH DEREK J; JANEY JACOB; KOSJEK BIRGIT; TANG WENG LIN; HSIEH HELEN; PHAM SON Q
权利人:CODEXIS INC
摘要:The present disclosure relates to transaminase polypeptides capable of aminating a dicarbonyl substrate, and polynucleotides, vectors, host cells, and methods of making and using the transaminase polypeptides.

专利号:US-2023313155-A1
优先权日:2011-09-08
标题 :Biocatalysts and methods for the synthesis of substituted lactams

专利号:US-10858635-B2
优先权日:2011-09-08
标题 :Biocatalysts and methods for the synthesis of substituted lactams

专利号:US-11597918-B2
优先权日:2011-09-08
标题 :Biocatalysts and methods for the synthesis of substituted lactams

专利号:US-12297462-B2
优先权日:2017-06-14
标 题:Engineered transaminase polypeptides for industrial biocatalysis
发明人：NOVICK SCOTT J; DELLAS NIKKI; ALVIZO OSCAR; Garcia Ravi David; CHING CHARLENE; ENTWISTLE DAVID
权利人:CODEXIS INC
摘要:The present invention provides engineered transaminase polypeptides useful for the synthesis of chiral amine compounds under industrially relevant conditions. The invention also provides polynucleotides encoding the engineered transaminase polypeptides, host cells capable of expressing the engineered transaminases, and methods of using the engineered transaminases for the production of chiral amine compounds.