CAS: 131-01-1; Methyl (1S,2R,3R,4As,13Br,14As)-2-Methoxy-3-((3,4,5-Trimethoxybenzoyl)Oxy)-1,2,3,4,4A,5,7,8,13,13B,14,14A-Dodecahydroindolo[2',3':3,4]Pyrido[1,2-B]Isoquinoline-1-Carboxylate

上下游产品

CAS号4521-61-3 3,4,5-三甲氧基苯甲酰氯 | CAS号61-54-1 色胺

Reserpinsaeurelacton置于吡啶,甲酸,三氟甲磺酸酐,1,1'-Ferrocenediyl-Bis(Tert-Butyl(Pyridin-2-yl)Phosphine),Sodium Methylate,Palladium Diacetate,三溴化硼,三乙胺体系中,用 四氢呋喃,甲醇,二氯甲烷 用作溶剂,化学反应 17.5H,反应生成蛇根平定
参考文献:Cn116693524
标题:Cn116693524

专利信息

专利号:US-10925977-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
发明人：YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S
权利人:YANG DAVID J; YU DONGFANG; THOMPSON ANDREW S; CEIL POINT LLC; UNIV TEXAS
摘要:Novel methods of synthesis of chelator-targeting ligand conjugates, compositions comprising such conjugates, and therapeutic and diagnostic applications of such conjugates are disclosed. The compositions include chelator-targeting ligand conjugates optionally chelated to one or more metal ions. Methods of synthesizing these compositions in high purity are also presented. Also disclosed are methods of imaging, treating and diagnosing disease in a subject using these novel compositions, such as methods of imaging a tumor within a subject and methods of diagnosing myocardial ischemia.

专利号:US-8735558-B2
优先权日:2005-02-14
标 题 :Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof
发明人：CHAN PUI-KWONG; MAK MAY SUNG
权利人:CHAN PUI-KWONG; MAK MAY SUNG; PACIFIC ARROW LTD
摘要:This invention provides methods, processes, compounds and compositions for modulating the gene expression and modulating the secretion, expression, or synthesis of adhesion proteins or their receptors to cure disease, wherein the modulating comprises positive and negative regulating; wherein comprises inhibiting cancer growth, wherein the adhesion proteins or receptors comprise fibronectin, integrins family, Myosin, vitronectin, collagen, laminin, Glycosylation cell surface proteins, polyglycans, cadherin, heparin, tenascin, CD 54, CAM, elastin and FAK; wherein the methods, processes, compounds and compositions are also for anti-angiogenesis; wherein the cancers comprise breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, prostate cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, CNS cancer, melanoma cancer, renal cancer or cervix cancer.

专利号:US-7468438-B2
优先权日:2004-03-25
标题:Process for the semisynthesis of deserpidine
发明人：FONTANA GABRIELE; BOMBARDELLI EZIO; SAMORI CRISTIAN; BALDELLI ELEONORA; GUERRINI ANDREA; BATTAGLIA ARTURO; DANIELI BRUNO
权利人:INDENA SPA
摘要:The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III).

专利号:US-RE41998-E
优先权日:1990-02-26
标题 :Compositions and methods of treatment of sympathetically maintained pain
发明人：CAMPBELL JAMES N
权利人:ARCLON THERAPEUTICS INC
摘要:Sympathetically maintained pain is treated topically by administering to the site where sympathetically maintained pain is present an α-1-adrenergic antagonist, α-2-adrenergic agonist, or other drug that depletes or blocks synthesis of sympathetic norepinephrine, known collectively as sympatholytic agents. Chemical formulas for several sympatholytic agents are given.

专利号:US-7300639-B2
优先权日:2002-12-03
标 题:Process for removing metals from liquids
发明人：LIU WANSHENG
权利人:BRISTOL MYERS SQUIBB CO
摘要:A process is provided for removing one or more metals from liquids. Also provided is a process for the synthesis of aP2 inhibiting compounds having the formula (I) n nwherein R 1 , R 2 , R 3 , R 4 , HET, and X-Z are as described herein, which process comprising the step of removing one or more metals from a solution of the compound of formula I or an intermediate or precursor thereof. The processes for removing metal comprise the step of contacting the liquid with a solid extractant comprising a metal-binding functionality.

专利号:US-10814013-B2
优先权日:2006-10-05
标 题 :Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications