专利号:US-2016223559-A1 优先权日:2015-02-02 标题:Tetrazine-containing compounds and synthetic methods thereof 发明人:DEVARAJ NEAL K; WU HAOXING; YANG JUN 权利人:UNIV CALIFORNIA 摘要:Described herein are tetrazine derivatives and efficient synthetic methods of synthesis thereof using elimination-Heck cascade reaction. Provided herein is the synthesis of conjugated tetrazines from the tetrazine derivatives. Also provided herein are methods of use of the conjugated tetrazines as fluorogenic probes for live-cell imaging.
参考标题:Tetrazine-Containing Compounds And Synthetic Methods Thereof 摘要:Described Herein Are Tetrazine Derivatives And Efficient Synthetic Methods Of Synthesis Thereof Using Elimination-Heck Cascade Reaction. Provided Herein Is The Synthesis Of Conjugated Tetrazines From The Tetrazine Derivatives. Also Provided Herein Are Methods Of Use Of The Conjugated Tetrazines As Fluorogenic Probes For Live-Cell Imaging.