CAS: 1069-23-4; 1,5-Hexadiene-3,4-Diol

上下游产品

CAS号1200-22-2 (R)-(+)-1,2-二硫戊...

丙烯醛置于氯化铵,锌体系中,用 四氢呋喃,水 用作溶剂,以70%的收率获得1,5-己二烯-3,4-二醇
参考文献:钯介导的磷依赖的化学选择性双烯丙基烷基化反应导致螺碳环
标题:钯介导的磷依赖的化学选择性双烯丙基烷基化反应导致螺碳环
摘要:无处不在的循环:钯催化的双烯丙基烷基化反应将1,3-二酮转化为碳环的选择性在很大程度上取决于所用的膦(参见方案).而且,合成的乙烯基环戊烯可以通过碳碳烯丙基键裂解容易地转化成环庚二烯衍生物.
Doi:10.1002/anie.201204629

专利信息

专利号:US-6262251-B1
优先权日:1995-10-19
标题 :Method for solution phase synthesis of oligonucleotides
发明人：PIEKEN WOLFGANG; MCGEE DANNY; SETTLE ALECIA; ZHAI YANSHENG; HUANG JIANPING
权利人:PROLIGO LLC
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides. The method lends itself to automation and is ideally suited for large scale manufacture of oligonucleotides with high efficiency.

专利号:US-5874532-A
优先权日:1997-01-08
标 题 :Method for solution phase synthesis of oligonucleotides and peptides
发明人：PIEKEN WOLFGANG; GOLD LARRY
权利人:NEXSTAR PHARMACEUTICALS INC
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides and peptides. The method lends itself to automation and is ideally suited for large scale manufacture oligonucleotides with high efficiency.

专利号:US-6001966-A
优先权日:1995-10-19
标题 :Method for solution phase synthesis of oligonucleotides and peptides
发明人：PIEKEN WOLFGANG; GOLD LARRY
权利人:PROLIGO LLC
摘要:This invention discloses an improved method for the sequential solution phase synthesis of oligonucleotides and peptides. The method lends itself to automation and is ideally suited for large scale manufacture oligonucleotides with high efficiency.

专利号:US-2009311292-A1
优先权日:2006-09-14
标题:Process for synthesis and incorporation of nitric oxide donors in macromolecular compositions
发明人：PACHECO OGARI; MOREIRA ROBERTO; SEABRA AMEDEA; SOUZA GABRIELA; OLIVEIRA MARCELO
权利人:CRISTALIA PROD QUIMICOS FARM; UNIV ESTADUAL DE CAMPINASUNICA
摘要:The present invention describes a process for the synthesis of S-nitrosothiols and the subsequent incorporation of these compounds in hydrophilic macromolecular compositions. By the process described herein, the S-nitrosothiols are synthesized in a device (FIG. 2 ) in a first step from the S-nitrosation reaction of their respective precursor thiols (A), promoted by a mechanical action that puts the thiols in contact with the nitrous acid formed from nitrite anions in acidic medium (B), and in a second mechanical operation, the freshly formed S-nitrosothiols are incorporated in an application vehicle (C) based on hydrophilic macromolecular compositions that increases their thermal stability. Therefore, the process under consideration combine the pre-application synthesis of S-nitrosothiols with their subsequent incorporation in delivery vehicles, with provide a relative stabilization of the S-nitrosothiols for sufficient periods so that the formulations prepared by this process may be stored in a domestic refrigerator during its time of use in its several possible applications.

专利号:US-8563760-B2
优先权日:2009-08-31
标 题:Process for the synthesis of long-chain fatty acids
发明人：FAUQ ABDUL H; EDWARDS ALBERT O
权利人:FAUQ ABDUL H; EDWARDS ALBERT O; MAYO FOUNDATION
摘要:This invention relates to processes for preparing long-chain fatty acids of Formula I: n nand salts thereof, as well as intermediates for the processes, wherein L 1 and L 2 are described herein.

专利号:US-3795682-A
优先权日:1970-07-27
标题 :Synthesis of cyclic ketals
发明人：DELAVARENNE S
权利人:UNION CARBIDE CORP
摘要:CYCLIC KETALS ARE PRODUCED BY CONTACTING A DEHYDRATING AGENT WITH A COMPOUND OF THE FORMULA: HO-C(-R2)(-R3)-X1-R1-X2H WHEREIN X1 REPRESENTS OXY, THIO, OR NITRILO, WHEREIN X2 REPRESENTS OXY, THIO, OR IMINO, PROVIDED THAT AT LEAST ONE OF X1 AND X2 REPRESENTS OXY, WHEREIN R1 REPRESENTS AN ALKYLENE GROUP OF FROM 2 TO 4 CARBON ATOMS OR A 2BUTYLENE GROUP, AND WHEREIN R2 AND R3 INDIVIDUALLY REPRESENT HALOGENATED ALKYL GROUPS THE ALPHA CARBON ATOMS BEING FLUORO, CHLORO, OR BROMO. THE CYCLIC KETALS PROGROUP, THE REMAINDER OF THE HALO GROUPS ON THE ALKYL BEING FLUORO, CHLORO, OR BROMO. THE CYCLIC KETALS PRODUCED ARE REPRESENTED BY THE FORMULA: R2-C(-R3)<(-O-R4-X1-) WHEREIN X1, R2, AND R3 ARE AS DEFINED ABOVE, AND WHEREIN R4 REPRESENTS ALKYLENE OF 2 TO 4 CARBON ATOMS OR SUBSTITUTED ALKYLENE. THE DEHYDRATING AGENTS EMPLOYED INCLUDE CARBODIIMIDES AND ALPHA-AMINOACETYLENES. THE PROCCESS OF THE INVENTION IS USEFUL FOR THE PREPARATION OF 1,3DIOXOLANES, 1,3 - DIOXANES, 1,3 - DIOXEPANES, AND THEIR ANALOGUES WHEREIN ONE OF THE OXYGEN ATOMS IN THE HETEROCYCLIC RING IS REPLACED BY EITHER A SULFUR ATOM OR NITRILO GROUP.