CAS: 100393-41-7; 3-Amino-3-(Naphthalen-1-yl)Propanoic Acid

上下游产品

CAS号141-82-2 丙二酸 | CAS号66-77-3 1-萘甲醛

📜丙二酸,1-萘甲醛置于ammonium Acetate体系中,用 乙醇 用作溶剂,化学反应 6.0H,以38%的收率获得3-氨基-3-萘-1-丙酸
参考文献:使用h2O2,钌催化烯烃的不对称环氧化,第一部分:合成新的手性n,N,N-三齿pybox和pyboxazine配体及其钌配合物.
标题:使用h2O2,钌催化烯烃的不对称环氧化,第一部分:合成新的手性n,N,N-三齿pybox和pyboxazine配体及其钌配合物.
摘要:详细描述了手性三齿n,N,N-吡啶-2,6-双恶唑啉3(pyboxbox配体)和n,N,N-吡啶-2,6-双恶嗪4(pyboxazine配体)的合成.这些新的配体构成了用于不对称催化的有用工具箱.化合物3和4可方便地通过对映体纯的α-或β-氨基醇与二甲基吡啶-2,6-二羧酸二亚氨基酯环化而制备.相应的钌配合物是有效的不对称环氧化催化剂,并以高收率制备并通过光谱学手段充分表征.这些钌络合物中的四个已通过x射线晶体学表征.哒嗪络合物[2,6-双-[(4S)-4-苯基-5,6-二氢-4H-[1,3]恶嗪基]吡啶](吡啶-2,6的分子结构首次)-二羧酸四硼酸酯)钌(S)-2 Aa,
Doi:10.1002/chem.200501261

专利信息

专利号:RU-2727723-C1
优先权日:2016-09-29
标 题 :Method for synthesis of novel chiral ligand, metal chelate, various unnatural amino acids, maraviroc and main intermediate compounds thereof

专利号:US-7388112-B2
优先权日:2003-05-23
标题 :Immunomodulation with novel pharmaceutical compositions
发明人：BURNS MARK R; MCVEAN MARALEE; KENNEDY KEVIN; YEUNG ARTHUR; DEVENS BRUCE H
权利人:MEDIQUEST THERAPEUTICS INC
摘要:The synthesis and use of a novel class of tumor necrosis factor (TNFα) inhibitors and immunomodulators are provided. Examples are those having the structures: n nwherein a, b and c are integers from 0 to 12, X equals NH or CHNH 2 , R 1 and R 2 each is a hydrogen or a C 1 to C 20 aliphatic; aliphatic amine; an alicyclic; aromatic; heterocycle; and halogenated forms thereof; andn n n n n n n n n n n n n wherein, a, b and c are integers from 0 to 12; R 1 , R 2 , R 3 , and R 4 each is a hydrogen or a C 1 to C 20 ; aliphatic amine; an alicyclic; aromatic; a heterocycle; and halogenated forms thereof.