CAS: 99323-21-4; 1-(4-Ethylphenyl)-2-Methyl-3-(Pyrrolidin-1-yl)Propan-1-One

上下游产品

对乙基苯丙酮 1-(4-Ethylphenyl)-1-Propanone 27465-51-6

📜四氢吡咯 反应生成 依那立松
参考文献:Itho,Yasuo;Kato,Hideo;Ogawa,Nobuo;Koshinaka,Eiichi;Nishino,Hiroyuki
标题:Itho,Yasuo;Kato,Hideo;Ogawa,Nobuo;Koshinaka,Eiichi;Nishino,Hiroyuki

专利信息

专利号:US-8183409-B2
优先权日:2004-05-06
标题:High yield and rapid synthesis methods for producing metallo-organic salts
发明人：CHRISTGAU STEPHAN; ANDERSEN JENS E T
权利人:CHRISTGAU STEPHAN; ANDERSEN JENS E T; OSTEOLOGIX AS
摘要:A new method for preparing salts of metal cations and organic acids, especially divalent salts of alkaline earth metal ions from group II of the periodic system and carboxylic acids. The method comprising the use of a high temperature (about 90° or more) and, optionally. high pressure, in order to obtain a higher yield, purity and faster reaction speed than obtained with known synthesis methods. In particular, the present invention relates to the production of strontium salts of carboxylic acids. Novel strontium salts are also provided by the present method.

专利号:US-2022118123-A1
优先权日:2019-02-22
标 题 :Combination of ar antagonists and targeted thorium conjugates
发明人：HAMMER STEFANIE; HAGEMANN URS BEAT; HAENDLER BERNARD; LEJEUNE PASCALE; ZITZMANN-KOLBE SABINE; SCHATZ CHRISTOPH; KARLSSON JENNY
权利人:BAYER AG; BAYER AS
摘要:The present invention covers combinations of at least two components, component A and component B, comprising component A being PSMA-TTC, and component B being an antiandrogen selected form AR antagonists such as from cyproterone acetate, bicalutamide, flutamide, nilutamide, enzalutamide, apalutamide, darolutamide or keto-darolutamide, or an AR degrader such as ARV-110, or an ARN-terminal domain binder such as EPI-506, or an antisense oligonucleotide that reduces AR expression such as EZN-4176 or AZD-5312, or an androgen synthesis inhibitor such as abiraterone, particularly abiraterone acetate, seviteronel, galeterone, orteronel or ketoconazole, or a dual AR antagonist and androgen synthesis inhibitor such as ODM-204. Another aspect of the present invention covers the use of such combinations as described herein for the preparation of a medicament for the treatment or prophylaxis of a disease, particularly for the treatment of a hyper-proliferative disease.

专利号:US-2009137678-A1
优先权日:2005-07-06
标 题:High yield synthesis methods for producing organic salts of strontium
发明人：CHRISTGAU STEPHAN; ANDERSEN JENS E T
权利人:CHRISTGAU STEPHAN; ANDERSEN JENS E T
摘要:New organic salts of strontium and methods of synthesizing such salts with high purity, high yields and with short processing times, at neutral conditions and at low reaction temperature, such as a temperature at or below 50° C.

专利号:US-10155069-B2
优先权日:2016-09-09
标 题 :Bone graft with a tannin-hydroxyapatite scaffold and stem cells for bone engineering
发明人：ABDALLA SOLIMAN MAHMOUD SOLIMAN; AL-MARZOUKI FAHAD; PIZZI ANTONIO; Bahabri Fatma Salem
权利人:UNIV KING ABDULAZIZ
摘要:A biocompatible bone graft for implanting into a bone wound site or screening a bone disease drug, comprising a porous scaffold structure made from a tannin-hydroxyapatite resin, a population of osteocompetent stem cells, and a growth medium. Methods of synthesis and physical characterization of the porous scaffold structure are described, as well as biological testing of the osteocompetent stem cells of the bone graft.

专利号:US-8993819-B2
优先权日:2011-07-12
标 题 :Process for preparing cycloheptene
发明人：TELES JOAQUIM HENRIQUE; LIMBACH MICHAEL; DEHN RICHARD; DEUERLEIN STEPHAN; DANZ MANUEL
权利人:TELES JOAQUIM HENRIQUE; LIMBACH MICHAEL; DEHN RICHARD; DEUERLEIN STEPHAN; DANZ MANUEL; BASF SE
摘要:The present invention provides a process for preparing cycloheptene and derivatives thereof by ring-closing metathesis of unsymmetric 1,8-dienes whose C—C double bond at the 8 position is nonterminal. Cycloheptene and the cycloheptanone, cycloheptylamine, cycloheptanecarbaldehyde, cycloheptanecarboxylic acid and cycloheptanecarbonyl chloride conversion products thereof, and the derivatives thereof, are important synthesis units for active ingredient compounds. The ring-closing metathesis is preferably performed as a reactive distillation. The unsymmetric 1,8-dienes for the ring-closing metathesis can be obtained by catalytic decarbonylation or oxidative decarboxylation from the corresponding unsaturated carboxylic acids or carboxylic acid derivatives.

专利号:WO-2007003200-A2
优先权日:2005-07-06
标题:High yield synthesis methods for producing organic salts of strontium