CAS: 94-08-6; Ethyl 4-Methylbenzoate

上下游产品

CAS号64-17-5 乙醇 | CAS号201230-82-2 carbon monoxide | CAS号624-31-7 对碘甲苯 | CAS号104-87-0 对甲基苯甲醛 | CAS号1906-57-6 乙基草酸钾 | CAS号1858-67-9 4-tolyl p-fluor... | CAS号106-38-7 对溴甲苯 | CAS号3899-96-5 1-methyl-4-(4-m... | CAS号26496-94-6 4-(溴甲基)苯甲酸乙酯 | CAS号874-60-2 对甲基苯甲酰氯 | CAS号50820-64-9 吲哚-6-甲酸乙酯 | CAS号31130-15-1 5-(4-甲基苯基)-1,3,... | CAS号3247-00-5 三-对甲苯基甲醇 | CAS号199938-21-1 N'-(氯乙酰基)-4-甲基苯甲酰肼 | CAS号2318-82-3 N-hydroxy-4-met... | CAS号21381-67-9 N-(2-Aminoethyl... | CAS号80648-69-7 N,N'-1,2-ethane... | CAS号122-00-9 对甲基苯乙酮 | CAS号589-18-4 4-甲基苄醇 | CAS号3619-22-5 对甲苯肼

Ethyl 2-(4-Methoxyphenylamino)-2-P-Tolylacetate置于2,2'-联吡啶,Palladium(II) Trifluoroacetate,苯硼酸体系中,用 硝基甲烷 作为反应溶剂,化学反应 48.0H,以85%的收率获得产物对甲基苯甲酸乙酯
参考文献:An Unusual 1,2-Aryl Shift In Palladium-Catalyzed Cross-Coupling Ethoxycarbonylation Of Arylboronic Acids With α-Iminoesters
标题:An Unusual 1,2-Aryl Shift In Palladium-Catalyzed Cross-Coupling Ethoxycarbonylation Of Arylboronic Acids With α-Iminoesters
摘要:钯催化的芳基硼酸与n-芳基α-亚胺酯的交叉偶联乙氧羰基化反应,通过碳基-亚胺σ键断裂形成芳基羧酸酯.这种前所未有的反应模式允许将乙氧羰基团区域选择性地安装到目标分子中.机理研究表明,在该转化过程中涉及了一种不寻常的1,2-芳基迁移过程.
DOI:10.1039/c3Ob41011K

专利信息

专利号:US-6841559-B1
优先权日:1999-11-19
标 题:Pyridinones to treat and prevent bacterial infections
发明人：ALMQVIST FREDERIC; EMTENAS HANS; HULTGREN SCOTT J; PINKNER JEROME S
权利人:WASHINGTON UNIVERSITY OF ST LO
摘要:Novel pyridinones and their derivatives which are effective in treating or preventing Gram-negative bacterial infections are provided. The pyridinones are stable and easily derivatized; the methods by which these derivatizations occur is described. Two regioselective and functional group tolerant methods for the synthesis of the novel pyridinones are also provided. One such synthetic method involves reacting an imine and a Meldrum's acid derivative in solution. The other synthetic method is a solid phase synthesis of the pyridinones in which an imine is prepared bound to a solid support and a Meldrum's acid derivative is reacted with the imine. Novel imine intermediates useful in the solid phase and solution methods of synthesizing the pyridionones are also described.

专利号:US-6048991-A
优先权日:1990-11-16
标题:Preparation of epoxides
发明人：HAERMELING DIETER
权利人:BASF AG
摘要:Alpha-hydroxy-epoxides of alpha-alkoxy-epoxides of the formula IV ##STR1## in which the substituents have the following meanings: R 7 , R 8 , R 9 , R 10 , R 11 are independently hydrogen, C 1 -C 20 -alkyl, C 3 -C 12 -cycloalkyl, C 4 -C 20 -cycloalkylalkyl, C 1 -C 20 -hydroxy-alkyl, a heterocyclic ring, or an aryl or C 7 -C 20 -arylalkyl group optionally substituted by C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, halogen, C 1 -C 4 -haloalkyl, C 1 -C 4 -halo-alkoxy, phenyl, phenoxy, halophenyl, halophenoxy, carboxy, C 2 -C 8 -alkoxycarbonyl, or cyano, or R 7 and R 8 or R 7 and R 9 or R 7 and R 10 or R 9 and R 10 or R 10 and R 11 together form a (CH 2 ) n group in which n is an integer from 1 to 10 and which may be optionally substituted by C 1 -C 8 -alkyl, C 1 -C 8 -alkoxy, and/or halogen, and n R 12 is hydrogen, C 1 -C 8 -alkyl, or benzyl, n provided that R 10 is not hydrogen, methyl, ethyl, propyl, or cyclohexyl when R 7 , R 8 , R 9 , or R 11 is hydrogen, that R 7 is not methyl when R 8 is methyl or phenyl and R 9 , R 10 , or R 11 is hydrogen, that R 7 is not methyl when R 8 , R 9 , R 10 , or R 11 is hydrogen and R 12 is ethyl, that R 7 is not phenyl or hexyl when R 8 , R 9 , R 10 , or R 11 is hydrogen, that R 9 is not methyl when R 7 , R 8 , R 10 , or R 11 is hydrogen, that R 10 and R 11 are not methyl when R 7 , R 8 , or R 9 is hydrogen, and that R 7 and R 10 do not together form an unsubstituted cycloalkyl when R 8 , R 9 , or R 11 is hydrogen. The epoxides of the above formula serve as intermediates for the synthesis of, inter alia, perfumes, plant protectants and polymers.

专利号:US-7416765-B2
优先权日:2004-10-04
标 题 :Polymerizable liquid crystalline composition and liquid crystal film made from the composition
发明人：SEKI TAKASHI; NAKAMURA TOORU; MAZAKI HITOSHI
权利人:NIPPON OIL CORP
摘要:A polymerizable liquid crystalline composition comprises a side chain liquid crystalline polymer obtained by radical-copolymerizing a (meth)acrylic compound has an optically active site and a (meth)acrylic compound having an oxetanyl group, and a cation generator and thus have no functional group the synthesis of which is difficult, such as an epoxy group. The use of the polymerizable liquid crystalline composition provides a cholesteric liquid crystal film which is excellent in a capability of retaining the orientation after being aligned and fixed in a liquid crystal orientation and in mechanical strength without the necessity of a complicated operation such as photo irradiation under an inert gas atmosphere.

专利号:US-9481705-B2
优先权日:2008-08-19
标题:Modular radiochemistry synthesis system
发明人：SATYAMURTHY NAGICHETTIAR; BARRIO JORGE R; AMARASEKERA BERNARD; VAN DAM R MICHAEL; OLMA SEBASTIAN; WILLIAMS DIRK; EDDINGS MARK; SHEN CLIFTON KWANG-FU
权利人:UNIV CALIFORNIA
摘要:A modular chemical production system includes multiple modules for performing a chemical reaction, particularly of radiochemical compounds, from a remote location. One embodiment comprises a reaction vessel including a moveable heat source with the position thereof relative to the reaction vessel being controllable from a remote position. Alternatively the heat source may be fixed in location and the reaction vial is moveable into and out of the heat source. The reaction vessel has one or more sealing plugs, the positioning of which in relationship to the reaction vessel is controllable from a remote position. Also the one or more reaction vessel sealing plugs can include one or more conduits there through for delivery of reactants, gases at atmospheric or an elevated pressure, inert gases, drawing a vacuum and removal of reaction end products to and from the reaction vial, the reaction vial with sealing plug in position being operable at elevated pressures. The modular chemical production system is assembled from modules which can each include operating condition sensors and controllers configured for monitoring and controlling the individual modules and the assembled system from a remote position. Other modules include, but are not limited to a Reagent Storage and Delivery Module, a Cartridge Purification Module, a Microwave Reaction Module, an External QC/Analysis/Purification Interface Module, an Aliquotting Module, an F-18 Drying Module, a Concentration Module, a Radiation Counting Module, and a Capillary Reactor Module.

专利号:US-4996314-A
优先权日:1986-03-11
标题 :6-(disubstituted amino)carbapenem compounds
发明人：YOSHIOKA TAKEO; CHIDA NORITAKA; WATANABE AZUMA; FUKAGAWA YASUO; ISHIKURA TOMOYUKI
权利人:SANRAKU INC
摘要:A compound represented by the formula ##STR1## wherein R 1 represents a lower alkyl group or a lower haloalkyl group; R 2 represents a lower alkyl group, a lower haloalkyl group, an aralkyl group, or a group of the formula --COOR 4 or --SO 2 R 5 in which R 4 represents an aralkyl group or a substituted or unsubstituted alkyl group and R 5 represents an alkyl group or a substituted or unsubstituted aryl group; and R 3 represents a hydrogen atom or a carboxyl protecting group which can be easily split off. This compound is useful in the production of a 6-(disubstituted amino)carbapenem-series antibiotic. n The compounds of the formula ##STR2## wherein R 1 and R 2 are as defined above are important intermediates for the synthesis of the compounds of formula (I) and/or the aforesaid di-(substituted amino) carbapenem-series antibiotics.

专利号:US-7576245-B2
优先权日:2002-07-11
标题:Fluorous tagging and scavenging reactants and methods of synthesis and use thereof
发明人：ZHANG WEI; LUO ZHIYONG
权利人:FLUOROUS TECHNOLOGIES INC
摘要:The present invention includes methods and compositions for increasing the fluorous nature of an organic compound by reacting it with at least one fluorous compound to produce a fluorous tagged organic compound. The increased fluorous nature of the fluorous tagged organic compound can then be utilized to separate the fluorous organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom. The resultant fluorous tagged organic compound can be subjected to subsequent chemical transformations, wherein the fluorous nature of the tagged compound is utilized to increase the ease of separation of the fluorous tagged organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom, after each chemical transformation. The chemical transformations result in a second fluorous tagged organic compound wherein the fluorous nature of the second fluorous tagged organic compound can then be reduced by removing the fluorous group therefrom, thereby producing a second organic compound that may be employed as a pharmaceutical compound or intermediate, or a combinatorial library component.