2939-66-4 = 894-71-3 反应条件:1.1 Reagents: P-Toluenesulfonic Acid Solvents: Toluene 标题:Lactones. Xvii. A New Synthesis Of Nortriptyline 作者:Lehmann,Jochen; Voss,Petra 参考文献:Archiv Der Pharmazie (Weinheim 日期:1988 卷标:321(1) 页码:55-6
📜3',4',10,11-Tetrahydro-Spiro<5H-Dibenzocyclohepten-5,5'(2'H)-Furan>-2'-On,甲胺,氢化铝锂,盐酸 以71%的收率获得产物 参考文献:Lehmann,Jochen;Voss.,Petra,Arch. Pharm.,321,(1988) N 1,55-56 标题:Lehmann,Jochen;Voss.,Petra,Arch. Pharm.,321,(1988) N 1,55-56
专利号:US-2014315720-A1 优先权日:2012-10-24 标 题 :Polysaccharide ester microspheres and methods and articles relating thereto 发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY 权利人:CELANESE ACETATE LLC 摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
1: Derry S, Wiffen PJ, Aldington D, Moore RA. Nortriptyline for neuropathic pain in adults. Cochrane Database Syst Rev. 2015 Jan 8;1:CD011209. doi: 10.1002/14651858.CD011209.pub2. Review. doi: 10.1097/JCP.0b013e318212d7cb. Review. doi: 10.2165/11585950-000000000-00000. Review. Review. Review. Review. Review. Review. Japanese. Review. Review. Review.
合成参考文献
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