CAS: 6636-22-2; (S)-3-(4-Acetoxyphenyl)-2-Aminopropanoic Acid

上下游产品

O-acetyl-N-benzyloxycarbonyl L-tyrosine L-tyrosine acetic acid acetyl chlorideO-acetyl-N-((E)-2-methyl-3-phenyl-acryloyl)-tyrosineO-acetyl-N-((E)-2-methyl-3-phenyl-acryloyl)-tyrosine Z)-4-acetoxy-benzylidene)-2-((E)-1-methyl-2-phenyl-vinyl)-4H-oxazol-5-one4-((Z)-4-acetoxy-benzylidene)-2-((E)-1-methyl-2-phenyl-vinyl)-4H-oxazol-5-one L-Tyr(OAc) NCA N-(O-acetyl-N-cyclopentyloxycarbonyl-L-tyrosyl)-glycine methyl esterN-(O-acetyl-N-cyclopentyloxycarbonyl-L-tyrosyl)-glycine methyl ester

📜在 盐酸体系中,用 水 作为反应溶剂,化学反应生成 O-乙酰基-L-酪氨酸
参考文献:α-氨基烷基自由基向异喹啉的有机催化对映选择性加成
标题:α-氨基烷基自由基向异喹啉的有机催化对映选择性加成
摘要:借助手性磷酸和二氰基吡嗪衍生的生色团(dpz)光敏剂的双重有机催化体系,并在可见光照射下,将α-氨基酸衍生的氧化还原活性酯(rae)的对映选择性minisci型加到异喹啉中已经被开发出来.从rae产生的各种前手性α-氨基烷基已成功引入异喹啉,以高收率提供了一系列有价值的α-异喹啉取代的手性仲胺,具有非常好或优异的对映选择性.
DOI:10.1021/acs.Orglett.8B02791

专利信息

专利号:US-4267344-A
优先权日:1972-09-22
标 题:N-Substituted N-carboxyanhydrides of α-amino acids and their application in the preparation of peptides
发明人：HALSTROM JOHN B; KOVACS KAROLY G
权利人:PROTEINKEMISK INST TILKNYTTET
摘要:N-Substituted N-carboxyanhydrides of α-amino acids, useful in peptide syntheses, and peptide synthesis process using such compounds, are disclosed. The N-substituent is penta(lower alkoxy)benzyl, or optionally substituted 9-xanthyl, 9-thioxanthyl or 9-selenoxanthyl.

专利号:US-4960881-A
优先权日:1984-02-16
标 题 :α-chlorinated carbonates, their method of manufacture and application in the protection of the amine functions of amino acids
发明人：BARCELO GERARD; SENET JEAN-PIERRE; SENNYEY GERARD
权利人:POUDRES & EXPLOSIFS STE NALE
摘要:The invention relates to carbonates of formula: ##STR1## in which X is a fluorine, chlorine or bromine atom and R 1 is different from the ##STR2## group and represents: a substituted or non-substituted, saturated or unsaturated, aliphatic, araliphatic, primary, secondary, tertiary or cycloaliphatic radical. These α-chlorinated carbonates are prepared by the action of a compound of formula R 1 OH on a chloroformate of formula: ##STR3## in a solvent medium in the presence of an acid scavenger which is added after the two preceding compounds. They are used to block the amine function of amino acids. The α-chlorinated carbonate and amino acid are reacted in a solvent medium at a temperature of -5° to 100° C. in the presence of an acid scavenger. Blocked amines are very useful in peptide synthesis.