📜4-氯-2-硝基甲苯置于盐酸,Potassium Permanganate,水,Magnesium Sulfate,Tin(Ll) Chloride体系中,化学反应生成 甲基2-胺-4-氯苯酚酯 参考文献:Antimalarials. The Synthesis Of 2,4,7-Trichloroquinoline1 标题:Antimalarials. The Synthesis Of 2,4,7-Trichloroquinoline1 摘要: DOI:10.1021/ja01211A049
专利号:JP-2005529076-A 优先权日:2002-02-15 标题:Synthesis of quinazolinone
专利号:US-7161002-B2 优先权日:2002-02-15 标 题 :Syntheses of quinazolinones 发明人:BERGNES GUSTAVE; HA EDWARD; YIANNIKOUROUS GEORGE; KALARITIS PANOS; YONCE BRANDON E; WELDAY JR KURT ALAN 权利人:SMITHKLINE BEECHAM CORP 摘要:The present invention provides novel quinazolinone compositions of matter comprising enantiomerically pure compound represented by Formula I: n nor a pharmaceutically acceptable salt thereof, having a detectable amount of one or more starting material and/or reagent used in the synthesis thereof.
专利号:CA-2475879-A1 优先权日:2002-02-15 标 题 :Synthesis of quinazolinones
专利号:EP-1480980-A4 优先权日:2002-02-15 标 题 :SYNTHESIS OF QUINAZOLINONES
专利号:US-11801242-B2 优先权日:2018-10-09 标 题:Compositions and methods for adjuvant cancer therapeutics 发明人:ZHOU PEI; HONG JIYONG 权利人:UNIV DUKE 摘要:This invention relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to translesion synthesis (TLS) pathway. More particularly, this disclosure relates to small molecule inhibitors of TLS, methods of inhibiting TLS pathway with these compounds, and methods of treating diseases related to the TLS pathway.
专利号:US-2012220595-A1 优先权日:2009-11-12 标题:Deuterated Tyrosine Kinase Inhibitors 发明人:EPSTEIN DAVID M; JIN MEIZHONG; MULVIHILL MARK J 权利人:EPSTEIN DAVID M; JIN MEIZHONG; MULVIHILL MARK J; OSI PHARMACEUTICALS LLC 摘要:Compounds of Formula I, as shown below and defined herein: enriched in deuterium, and pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers mediated at least in part by IGF-1R and/or IR.
摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 227. 摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 296. 摘要:Wang, L.; Liu, M.; Cheng, J., Science of Synthesis: Knowledge Updates, (2024) 1, 193.