CAS: 5900-58-3; Methyl 2-Amino-4-Chlorobenzoate

该化合物是属于苯甲酸酯类别的有机化合物,其特征是附属于苯并酸衍生物的甲基酯功能组,包括一个氨基氨基酸组和芳香环上的氯替代体,该化合物的特点是白色至非白色晶晶状固体形式,在有机溶剂中具有中等溶解性;氨基组的存在具有基本特性,而氯原子可影响其再活性和极性.甲基2-氨基-4-氯苯甲酸酯经常用于有机合成,并可作为生产药品或农用化学剂的中间体.其化学结构允许各种反应,包括核分裂替代和组合反应,使其成为合成有机化学的一种有价值的化合物.在处理和储存时,应参考安全数据,与所有化学物质一样,以确保采取适当的预防措施.

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上下游产品

CAS号67-56-1 甲醇 | CAS号89-77-0 2-氨基-4-氯苯甲酸 | CAS号42087-80-9 4-氯-2-硝基苯甲酸甲酯 | CAS号77-76-9 2,2-二甲氧基丙烷 | CAS号186581-53-3 重氮甲烷 | CAS号6280-88-2 4-氯-2-硝基苯甲酸 | CAS号34662-32-3 4-氯-2-硝基苯甲腈 | CAS号89-63-4 邻硝基对氯苯胺 | CAS号5900-59-4 2-氨基-4-氯苯甲酰胺 | CAS号89-59-8 4-氯-2-硝基甲苯 | CAS号31374-18-2 7-氯-4(3H)-喹唑啉酮 | CAS号58331-97-8 4-氯-2-氰基苯甲酸甲酯 | CAS号38487-86-4 2-氨基-4-氯苯腈 | CAS号199850-56-1 4-氯-5-碘-2-氨基苯甲酸甲酯 | CAS号85392-01-4 4-氯-2-(氯磺酰基)苯甲酸甲酯 | CAS号5900-59-4 2-氨基-4-氯苯甲酰胺 | CAS号116815-03-3 8-氯-1,2,3,4-四氢苯... | CAS号335293-22-6 dimethyl 4-acet... | CAS号13165-35-0 7-氯喹唑啉-2,4-二酮 | CAS号1189106-03-3 4-bromo-7-chlor...

合成工艺路线路线简述

    📜4-氯-2-硝基甲苯置于盐酸,Potassium Permanganate,水,Magnesium Sulfate,Tin(Ll) Chloride体系中,化学反应生成 甲基2-胺-4-氯苯酚酯
    参考文献:Antimalarials. The Synthesis Of 2,4,7-Trichloroquinoline1
    标题:Antimalarials. The Synthesis Of 2,4,7-Trichloroquinoline1
    摘要:
    DOI:10.1021/ja01211A049

    海关参考信息

    专利信息


    专利号:JP-2005529076-A
    优先权日:2002-02-15
    标题:Synthesis of quinazolinone

    专利号:US-7161002-B2
    优先权日:2002-02-15
    标 题 :Syntheses of quinazolinones
    发明人:BERGNES GUSTAVE; HA EDWARD; YIANNIKOUROUS GEORGE; KALARITIS PANOS; YONCE BRANDON E; WELDAY JR KURT ALAN
    权利人:SMITHKLINE BEECHAM CORP
    摘要:The present invention provides novel quinazolinone compositions of matter comprising enantiomerically pure compound represented by Formula I: n nor a pharmaceutically acceptable salt thereof, having a detectable amount of one or more starting material and/or reagent used in the synthesis thereof.

    专利号:CA-2475879-A1
    优先权日:2002-02-15
    标 题 :Synthesis of quinazolinones

    专利号:EP-1480980-A4
    优先权日:2002-02-15
    标 题 :SYNTHESIS OF QUINAZOLINONES

    专利号:US-11801242-B2
    优先权日:2018-10-09
    标 题:Compositions and methods for adjuvant cancer therapeutics
    发明人:ZHOU PEI; HONG JIYONG
    权利人:UNIV DUKE
    摘要:This invention relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to translesion synthesis (TLS) pathway. More particularly, this disclosure relates to small molecule inhibitors of TLS, methods of inhibiting TLS pathway with these compounds, and methods of treating diseases related to the TLS pathway.

    专利号:US-2012220595-A1
    优先权日:2009-11-12
    标题:Deuterated Tyrosine Kinase Inhibitors
    发明人:EPSTEIN DAVID M; JIN MEIZHONG; MULVIHILL MARK J
    权利人:EPSTEIN DAVID M; JIN MEIZHONG; MULVIHILL MARK J; OSI PHARMACEUTICALS LLC
    摘要:Compounds of Formula I, as shown below and defined herein: enriched in deuterium, and pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancers mediated at least in part by IGF-1R and/or IR.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 227.
    摘要:Silva, V. L. M.; Pinto, D. C. G. A.; Santos, C. M. M.; Rocha, D. H. A., Science of Synthesis Knowledge Updates, (2022) 3, 296.
    摘要:Wang, L.; Liu, M.; Cheng, J., Science of Synthesis: Knowledge Updates, (2024) 1, 193.
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