CAS: 5367-32-8; 3-Methyl-4-Nitroanisole

该化合物是属于硝酸盐类的有机化合物,其特点是在厌食结构上存在一个甲基组和一个硝基组,分子式为C9H10N2O3,表明含有碳,氢,氮和氧原子.该化合物一般是黄色至橙色晶体固体,由于存在甲基氧化合物组而闻名其芳香特性.该化合物在有机溶剂中具有中度溶性,在水中溶性有限.3-M乙基-4-nitroaniole经常用于有机合成,并用作染料,药品和农用化学品生产的中间体.该混合物有助于其再活性,使其成为各种化学反应中的有用建筑块.在处理该化合物时,应采取安全防范措施,因为如果吸入或浸泡,可能会对健康造成危害,并应采取适当措施来减少接触.

结构式图片

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号2581-34-2 4-硝基间甲苯酚 | CAS号100-17-4 4-硝基苯甲醚 | CAS号676-58-4 甲基氯化镁 | CAS号77-78-1 硫酸二甲酯 | CAS号109434-09-5 (5-methoxy-2-ni... | CAS号100-19-6 对硝基苯乙酮 | CAS号100-84-5 间甲基苯甲醚 | CAS号509-14-8 四硝基甲烷 | CAS号74-83-9 溴甲烷 | CAS号179691-27-1 2-(5-methoxy-2-... | CAS号21857-41-0 methyl 2-(5-met... | CAS号27798-66-9 5-甲氧基吲哚-2-乙酸甲酯 | CAS号1882-69-5 5-甲氧基-2-硝基苯甲酸 | CAS号20876-29-3 2-硝基-5-甲氧基苯乙酸 | CAS号31601-41-9 2-乙酰氨基-5-甲氧基甲苯 | CAS号27060-75-9 2-溴-5-甲氧基甲苯 | CAS号5883-96-5 5-甲氧基-2-苯基-1H-吲哚 | CAS号1076-74-0 5-甲氧基-2-甲基吲哚 | CAS号102-50-1 2-甲基-4-甲氧基苯胺

合成工艺路线路线简述

    间甲基苯甲醚置于硝酸,溶剂黄146体系中,化学反应生成 3-甲基-4-硝基苯甲醚
    参考文献:Wieland Et Al.,Justus Liebigs Annalen Der Chemie,1934,Vol. 513,P. 1,18
    标题:Wieland Et Al.,Justus Liebigs Annalen Der Chemie,1934,Vol. 513,P. 1,18

    海关参考信息

    专利信息


    专利号:US-5763599-A
    优先权日:1994-12-16
    标题:Nucleoside derivatives with photolabile protective groups
    发明人:PFLEIDERER WOLFGANG; GIEGRICH HEINER
    权利人:PFLEIDERER WOLFGANG
    摘要:The invention relates to nucleoside derivatives having photolabile protective groups of the general formula (I) ##STR1## in which R 1 â•?H, NO 2 , CN, OCH 3 , halogen or alkyl or alkoxyalkyl having 1 to 4 C atoms n R 2 â•?H, OCH 3 n R 3 â•?H, F, Cl, Br, NO 2 n R 4 â•?H, halogen, OCH 3 , or an alkyl radical having 1 to 4 C atoms n R 5 â•?H or a usual functional group for preparing oligonucleotides n R 6 â•?H, OH, halogen or XR 8 , where Xâ•?O or S and R 8 represents a protective group usual in nucleotide chemistry, n B=adenine, cytosine, guanine, thymine, uracil, 2,6-diaminopurin-9-yl, hypoxanthin-9-yl, 5-methylcytosin-1-yl, 5-amino-4-imidazolcarboxamid-1-yl, or 5-amino-4-imidazolcarboxamid-3-yl, where in the case of B=adenine, cytosine or guanine, the primary amino function optionally exhibits a permanent protective group. n These derivatives may be used for the light-controlled synthesis of oligonucleotides on a DNA chip.

    专利号:US-8372380-B2
    优先权日:2007-03-30
    标 题:In vivo imaging of sulfotransferases
    发明人:BARRIO JORGE R; KEPE VLADIMIR; SMALL GARY W; SATYAMURTHY NAGICHETTIAR
    权利人:UNIV CALIFORNIA; BARRIO JORGE R; KEPE VLADIMIR; SMALL GARY W; SATYAMURTHY NAGICHETTIAR
    摘要:Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with 18 F, 123 I, 124 I, 125 I, or 11 C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.

    专利号:US-7115766-B2
    优先权日:2000-11-30
    标题 :Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
    发明人:MULHOLLAND G KEITH; O'DONNELL MARTIN J; CHIN FREDERICK T; DELGADO FRANCISCA
    权利人:UNIV INDIANA RES & TECH CORP
    摘要:Radiolabeled fluorinated compounds useful for imaging in the diagnosis of Parkinson's Disease are disclosed. Methods and kits for their synthesis are also disclosed.
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    主要参考文献

    [参考文献]: Andrew Tsotinis, Et Al. Design And Synthesis Of Potent N1-Substituted Indole Melatonin Receptor Agonists. Chem Commun (Camb). 2003 Feb 7:(3):382-3.

    合成参考文献


    摘要:S60 | SWISSPEST19 | Swiss Pesticides and Metabolites from Kiefer et al 2019 | DOI:10.5281/zenodo.3544759
    摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003).
    摘要:Joule, J. A., Science of Synthesis, (2001) 10, 407.
    摘要:Joule, J. A., Science of Synthesis, (2001) 10, 415.
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