📜间甲基苯甲醚置于硝酸,溶剂黄146体系中,化学反应生成 3-甲基-4-硝基苯甲醚 参考文献:Wieland Et Al.,Justus Liebigs Annalen Der Chemie,1934,Vol. 513,P. 1,18 标题:Wieland Et Al.,Justus Liebigs Annalen Der Chemie,1934,Vol. 513,P. 1,18
专利号:US-5763599-A 优先权日:1994-12-16 标题:Nucleoside derivatives with photolabile protective groups 发明人:PFLEIDERER WOLFGANG; GIEGRICH HEINER 权利人:PFLEIDERER WOLFGANG 摘要:The invention relates to nucleoside derivatives having photolabile protective groups of the general formula (I) ##STR1## in which R 1 â•?H, NO 2 , CN, OCH 3 , halogen or alkyl or alkoxyalkyl having 1 to 4 C atoms n R 2 â•?H, OCH 3 n R 3 â•?H, F, Cl, Br, NO 2 n R 4 â•?H, halogen, OCH 3 , or an alkyl radical having 1 to 4 C atoms n R 5 â•?H or a usual functional group for preparing oligonucleotides n R 6 â•?H, OH, halogen or XR 8 , where Xâ•?O or S and R 8 represents a protective group usual in nucleotide chemistry, n B=adenine, cytosine, guanine, thymine, uracil, 2,6-diaminopurin-9-yl, hypoxanthin-9-yl, 5-methylcytosin-1-yl, 5-amino-4-imidazolcarboxamid-1-yl, or 5-amino-4-imidazolcarboxamid-3-yl, where in the case of B=adenine, cytosine or guanine, the primary amino function optionally exhibits a permanent protective group. n These derivatives may be used for the light-controlled synthesis of oligonucleotides on a DNA chip.
专利号:US-8372380-B2 优先权日:2007-03-30 标 题:In vivo imaging of sulfotransferases 发明人:BARRIO JORGE R; KEPE VLADIMIR; SMALL GARY W; SATYAMURTHY NAGICHETTIAR 权利人:UNIV CALIFORNIA; BARRIO JORGE R; KEPE VLADIMIR; SMALL GARY W; SATYAMURTHY NAGICHETTIAR 摘要:Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with 18 F, 123 I, 124 I, 125 I, or 11 C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.
专利号:US-7115766-B2 优先权日:2000-11-30 标题 :Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds 发明人:MULHOLLAND G KEITH; O'DONNELL MARTIN J; CHIN FREDERICK T; DELGADO FRANCISCA 权利人:UNIV INDIANA RES & TECH CORP 摘要:Radiolabeled fluorinated compounds useful for imaging in the diagnosis of Parkinson's Disease are disclosed. Methods and kits for their synthesis are also disclosed.
[参考文献]: Andrew Tsotinis, Et Al. Design And Synthesis Of Potent N1-Substituted Indole Melatonin Receptor Agonists. Chem Commun (Camb). 2003 Feb 7:(3):382-3.
合成参考文献
摘要:S60 | SWISSPEST19 | Swiss Pesticides and Metabolites from Kiefer et al 2019 | DOI:10.5281/zenodo.3544759 摘要:Kleemann, A.; Engel, J.; Kutscher, B.; Reichert, D., Pharmaceutical Substances[Online], Thieme: Stuttgart, (2003). 摘要:Joule, J. A., Science of Synthesis, (2001) 10, 407. 摘要:Joule, J. A., Science of Synthesis, (2001) 10, 415.