CAS: 397864-40-3; 6α,9α-Difluoro-17α-(Furan-2-yl)Carbonyloxy-11β-Hydroxy-16α-Methyl-3-Oxoandrosta-1,4-Diene-17β-Carbothioic Acid

上下游产品

氟替卡松杂质 17β-[(N,N-Dimethylcarbornyl)Thio]-6α,9α-Difluoro-11β-Hydroxy-16α-Methyl-17α-(2-Furoyloxy)-3-Oxoandrosta-1,4-Diene 948565-92-2
氟替卡松杂质16 Gw694301X 397864-63-0
氟替卡松杂质31 (1R,2S,8S,10S,11S,13R,14R,15S,17S)-1,8-Difluoro-14-{[(Furan-2-yl)Carbonylsulfanyl]Carbonyl}-17-Hydroxy-2,13,15-Trimethyl-5-Oxotetracyclo[8.7.0.02,7.011,15]Heptadeca-3,6-Dien-14-Yl Furan-2-Carboxylate 397864-41-4
(6A,11B,16A,17A)-6,9-二氟-11,17-二羟基-16-甲基-3-氧代雄甾-1,4-二烯-17-硫代羧酸 6α,9α-Difluoro-11β,17α-Dihydroxy-16α-Methyl-3-Oxo-Androsta-1,4-Diene-17β-Carbothioic Acid 80473-92-3
5,9B-Difluoro-1,10-Dihydroxy-2,9A,11A-Trimethyl-7-Oxo-2H,3H,3Ah,3Bh,4H,5H,10H,11H-Cyclopenta[a]Phenanthrene-1-Carbothioic S-Acid
6,9-二氟-11,17-二羟基-16-甲基-3-氧代雄甾-1,4-二烯-17-羧酸 6α,9α-Difluoro-11β,17α-Dihydroxy-16α-Methyl-3-Oxoandrosta-1,4-Diene-17β-Carboxylic Acid 28416-82-2
氟米松 Flumetasone 2135-17-3

📜氟米松置于吗啉,Sodium Periodate,三乙胺,Sodium Iodide体系中,用 四氢呋喃,水,丙酮,丁酮 用作溶剂,化学反应 13.5H,反应生成氟替卡松杂质17
参考文献:Process For Preparing Fluticasone Propionate/furoate
标题:Process For Preparing Fluticasone Propionate/furoate
摘要:本发明涉及一种改进的制备取代氟替卡松衍生物的过程.该发明还揭示了用于纯化氟替卡松和相关中间体的过程,以提供高纯度产品.