专利号:US-10011567-B1 优先权日:2017-03-09 标题 :Method for the synthesis of acrylate derivatives 发明人:WANG MINGWEN; ZHANG YUE 权利人:INNOSCI LLC 摘要:The present invention provides an improved synthesis of a salt of acrylate derivatives. The synthesis generally includes the preparation of an ester or an amide containing a leaving group followed by the formation of a salt.
专利号:WO-2025122636-A1 优先权日:2023-12-04 标题:Method for the synthesis of acrylate derivatives 发明人:CAICEDO-CARVAJAL CARLOS; KATZ JORDAN; CHOI SEAN 权利人:ORTHOBOND CORP 摘要:The disclosure relates to the synthesis of quaternary salts of various acrylates in high yield and high purity.
专利号:US-6962963-B2 优先权日:2002-10-18 标题 :Enzymatic synthesis of polymers 发明人:KUMAR RAJESH; WATTERSON ARTHUR C; PARMAR VIRINDER SINGH; KUMAR JAYANT; SAMUELSON LYNNE ANN 权利人:UNIV MASSACHUSETTS 摘要:The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.
专利号:WO-9617589-A1 优先权日:1994-12-08 标 题 :Method of smoothing or removing wrinkles and method of stimulating collagen synthesis 发明人:FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO 权利人:KAO CORP; FUJIMURA TSUTOMU; OGAWA AYUMI; OHSU HIROYUKI; TAKEMA YOSHINORI; HORI KIMIHIKO; AMANO SHINYA; FUJIMORI TAKETOSHI; OHASHI YUKIHIRO; SUZUKI YASUTO 摘要:The present invention relates to methods of stimulating collagen synthesis and of smoothing or removing wrinkles, which comprise administering an effective amount of a benzoic acid derivative of formula (1) or a salt thereof, wherein X is -O- or -N(R4)- (R4 is H or the like), R1 is a C¿4-25 -alkyl or C4-25-alkenyl group, R 2¿ is H, OH, or a C¿1-6 -alkoxyl or C1-6-alkanoyloxy group, and R 3 is -OR5¿ or -N(R 6)R7 (R5 is H, or a C1-25-alkyl or C1-25-alkenyl group), and R 6 and R7¿ are individually H, or a C¿1-3 -alkyl or C1-3-alkenyl group, and use of this compound for agents for stimulating synthesis of collagen, and smoothing or removing wrinkles. This compound (1) stimulates collagen synthesis in human dermal fibroblasts and consequently smooths or removes wrinkles caused by aging and/or photoaging.
专利号:US-8563760-B2 优先权日:2009-08-31 标 题:Process for the synthesis of long-chain fatty acids 发明人:FAUQ ABDUL H; EDWARDS ALBERT O 权利人:FAUQ ABDUL H; EDWARDS ALBERT O; MAYO FOUNDATION 摘要:This invention relates to processes for preparing long-chain fatty acids of Formula I: n nand salts thereof, as well as intermediates for the processes, wherein L 1 and L 2 are described herein.
专利号:US-2017029451-A1 优先权日:2013-12-05 标 题:Branched chain acyclic nucleoside phosphonate esters and methods of synthesis and uses thereof 发明人:WARE ROY W; DOWNEY AARON L; LANIER ERNEST RANDALL; SETHNA PHIROZE; SELLESETH DEAN 权利人:CHIMERIX INC 摘要:The present invention is directed to branched chain nucleoside phosphonate ester compounds and methods of synthesis thereof. The present invention is also directed to pharmaceutical compositions comprising branched chain nucleoside phosphonate ester compounds and methods of treating and/or preventing double stranded DNA viral infection and/or viral infection associated disease or disorder.
[参考文献]: Yui Masuda, Et Al. Synthesis Of (2S,2'R,3S,4R)-2-(2'-Hydroxy-21'-Methyidocosanoylamino)-1,3,4-Pentadecanetriol, The Ceramide Sex Pheromone Of The Female Hair Crab, Erimacrus Isenbeckii. Biosci Biotechnol Biochem. 2002 Jul;66(7):1531-7.
合成参考文献
摘要:Joosten, A.; Brioche, J., Science of Synthesis: Modern Strategies in Organofluorine Chemistry , (2024) 1, 6.