CAS: 2156-04-9; 4-Vinylbenzeneboronic Acid

该化合物是一种有机化合物,具有乙烯基和黄酸功能组的特点,其特点是能够参与各种化学反应,特别是与二醇和其他核素形成共价联系,使其在有机合成和材料科学中具有价值;该化合物一般是白色的,白色的,白色的,可溶于水和酒精等极地溶剂;其碱酸混合物允许与生物分子发生可逆的相互作用,这对药物的开发和传感器应用特别有用;此外,4-vinybenzeneboromic酸可发生聚合作用,导致形成交叉联系网络,用于生产水文凝胶和其他先进材料;还注意到该化合物在医药化学方面的潜力,特别是由于能够形成稳定地与某些生物目标形成复合体,因此在开发有针对性的治疗方面的潜力.

结构式图片

欧盟法规

C&L通报

上下游产品

6H4-4-CHBrCH3)O}3{B(C6H4-4-CHBrCH3)O}3 (4-Vinylphenyl)magnesium chloride Trimethyl borate boric acid tributyl ester O,O'-(4-vinyl-phenylboranediyl)-Lg-tartaric acid diethyl esterO,O'-(4-vinyl-phenylboranediyl)-Lg-tartaric acid diethyl ester 2,4,6-tris-(4-vinylphenyl)cyclotriboroxane p-vinylphenylboronic diethanolamine ester diethoxy-(4-vinyl-phenyl)-borane

合成工艺路线路线简述

    Magnesium,Ethenylbenzene,Chloride置于硼酸三甲酯体系中,化学反应生成4-乙烯基苯硼酸
    参考文献:Braun,J.; Normant,H.,Bulletin De La Societe Chimique De France,1966,P. 2557-2564
    标题:Braun,J.; Normant,H.,Bulletin De La Societe Chimique De France,1966,P. 2557-2564

    海关参考信息

    专利信息


    专利号:US-8110642-B2
    优先权日:2006-05-08
    标 题:Synthesis of vinylphenylpyridine and living anionic polymerization
    发明人:LEE JAE-SUK; KANG NAM-GOO
    权利人:LEE JAE-SUK; KANG NAM-GOO; KWANGJU INST SCI & TECH
    摘要:Provided are a vinyl-biphenylpyridine monomer and a polymer thereof. More particularly, the present invention provides a vinyl-biphenylpyridine monomer having a side chain of pyridine or phenylpyridine as a functional group, a homopolymer of which molecular weight and molecular weight distribution are controlled using the monomer, and a block copolymer of which molecular structure and molecular weight are controlled to facilitate synthesis of an organic metal complex. Accordingly, the present invention provides a vinyl-biphenylpyridine monomer and a polymer thereof which are effectively used as nano and optical functional materials.

    专利号:WO-2021161084-A1
    优先权日:2020-02-16
    标题 :N-(4-fluorophenyl)-5-phenyl-[1,2,4] triazolo [1,5-a] pyridine-2-carboxamide derivatives and their synthesis thereof
    发明人:NINGEGOWDA RAGHU; BANUPRAKASH GOVINDAPPA; CHANDRASHEKHARAPPA SANDEEP
    权利人:NINGEGOWDA RAGHU; BANUPRAKASH GOVINDAPPA; CHANDRASHEKHARAPPA SANDEEP
    摘要:The present invention relates to the development of novel N-(4-fluorophenyl)-5-phenyl- [1,2,4]triazolo[1,5-a]pyridine-2-carboxamide derivatives for their different pharmacological activities. It particularly relates to the development of N-(4-fluorophenyl)-5-phenyl- [1,2,4]triazolo[1,5-a]pyridine-2-carboxamide derivatives as antiviral, anticancer, antifungal, hypoglycemic, anti-tubercular, sedative, anti-type 2 diabetes activity. It specifically relates to the N-(4-fluorophenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyridine-2-carboxamide derivatives for treatment of H37Rv and multidrug-resistant (MDR) strains of Mycobacterium tuberculosis (MTB). The present invention also relates to the process for synthesis of N-(4-fluorophenyl)- 5-phenyl-[1,2,4]triazolo[1,5-a]pyridine-2-carboxamide derivatives. The invention further relates to method for treatment of method for treatment of diseases such as tuberculosis, type 2 diabetes, bacterial, viral and fungal infections. Invention addresses the challenges in working with chemical processes and products by inventing novel reaction methodology that can maximize the desired products and minimize by-products, designing new synthetic schemes that can simplify operations in chemical productions and seeking nontoxic reagent that are inherently environmentally and ecologically benign. Synthesis of novel N-(4- fluorophenyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyridine-2-carboxamide derivatives is being employed to develop a novel synthetic methodology and their pharmacological applications. Novel series of N-(4-fluorophenyl)-5-phenyl-[1,2,4]triazolo[l,5-a]pyridine-2-carboxamide derivatives were designed synthesized evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of mycobacterium tuberculosis (MTB). All the synthesized compounds were characterized by spectroscopic methods like Mass, NMR and elemental analysis.

    专利号:US-7728088-B2
    优先权日:2002-08-06
    标题 :Synthesis of statistical microgels by means of controlled radical polymerisation
    发明人:DESTARAC MATHIAS; BAVOUZET BRUNO; TATON DANIEL
    权利人:RHODIA OPERATIONS
    摘要:The invention relates to a method of preparing statistical microgels. The inventive method comprises a step involving the radical polymerisation of a composition containing: at least one monoethylenically-unsaturated monomer, at least one multiethylenically-unsaturated monomer, a free radical source and a control agent. The invention also relates to first generation microgels thus prepared and all the compounds resulting from said microgels (next-generation microgels).

    专利号:US-2002001821-A1
    优先权日:1994-02-10
    标 题:Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof

    专利号:US-2006106178-A1
    优先权日:2002-08-06
    标题:Synthesis of statistical microgels by means of controlled radical polymerisation

    专利号:US-6127154-A
    优先权日:1994-02-10
    标题 :Methods for direct synthesis of compounds having complementary structure to a desired molecular entity and use thereof
    发明人:MOSBACH KLAUS; CORMACK PETER A G; RAMSTROEM OLOF; HAUPT KARSTEN
    摘要:Compounds which possess a complementary structure to a desired molecule, such as a biomolecule, in particular polymeric or oligomeric compounds, which are useful as in vivo or in vitro diagnostic and therapeutic agents are provided. Also, various methods for producing such compounds are provided. These polymeric or oligomeric compounds are useful in particular as antimicrobial agents, receptor, hormone or enzyme agonists and antagonists.
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    合成参考文献


    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2018) 3, 158.
    摘要:Sainsbury, M., Science of Synthesis Knowledge Updates, (2010) 1, 234.
    摘要:Kwiecień, H., Science of Synthesis Knowledge Updates, (2018) 3, 170.
    摘要:González-Bello, C., Science of Synthesis Knowledge Updates, (2018) 1, 220.
    摘要:Vashchenko, B. V.; Grygorenko, O. O., Science of Synthesis Knowledge Updates, (2021) 3, 297.
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