CAS: 5355-17-9; 4-(Methoxymethyl)Phenol

该化合物是一种多用途酚化合物,其特征是配在芳香环上的甲氧甲基功能组的存在,这一结构特征增强了其在有机溶剂中的溶性,同时保留了苯基衍生物的典型反应性.该化合物通常用作有机合成的中间体,特别是在特殊化学品,药品和农用化学品生产中.该化合物在温和条件下的稳定性和与各种反应途径的兼容性,使它成为建造更复杂的分子结构的宝贵建筑.甲基氧基甲基组还有可能进一步发挥功能,扩大其在精细化学合成中的适用性.

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CAS号67-56-1 甲醇 | CAS号623-05-2 对羟基苯甲醇 | CAS号2937-64-6 acetic acid 4-a... | CAS号106-44-5 对甲酚 | CAS号39720-27-9 4-(氯甲基)苯基乙酸酯 | CAS号123-08-0 4-羟基苯甲醛; 对羟基苯甲醛 | CAS号937-62-2 氯甲酸对甲苯酯 | CAS号124-41-4 甲醇钠 | CAS号61334-39-2 8-((ethoxycarbo... | CAS号15451-04-4 p-chloromethyl-... | CAS号145624-58-4 [4-(2-methylpro... | CAS号4167-74-2 4-异丁基苯酚 | CAS号123-08-0 4-羟基苯甲醛; 对羟基苯甲醛

合成工艺路线路线简述

    📜对甲酚置于5%-Palladium/activated Carbon,Potassium Acetate,Sodium Hydroxide体系中,用 水 作为反应溶剂,化学反应 12.33H,反应生成 4-甲氧甲基苯酚
    参考文献:Practical Process For The Air Oxidation Of Cresols: Part A. Mechanistic Investigations
    标题:Practical Process For The Air Oxidation Of Cresols: Part A. Mechanistic Investigations
    摘要:The Catalytic Air Oxidation Of P-Cresol And 2,6-Di-Tert-Butyl-4-Methylphenol To The Corresponding Benzaldehydes Was Investigated To Determine The Mechanism At Work In These Oxidation Reactions. A Number Of Intermediates And Byproducts,Mainly In The Form Of Dimers,Were Observed During The Course Of The Reactions,And Their Structures Were Elucidated By Spectroscopic And Chromatographic Methods. The Existence Of These Compounds In The Reaction Mixtures,And Their Proposed Methods Of Formation,Provided Further Insight Into The Mechanism Involved In These Oxidations.
    DOI:10.1021/op049845B

    海关参考信息

    专利信息


    专利号:US-2016318862-A1
    优先权日:2013-09-25
    标 题:Synthesis of delta 12-pgj3 and related compounds
    发明人:NICOLAOU KYRIACOS C; HERETSCH PHILIPP; HALE CHRISTOPHER R H; EL GHZAOUI ABDELLATIF EL MARROUNI; PULUKURI KIRAN KUMAR; YU RUOCHENG; GROVE CHARLES
    权利人:UNIV RICE WILLIAM M
    摘要:In one aspect, the present invention provides novel derivatives of Δ 12 -PGJ 3 and modular synthetic pathways to obtaining Δ 12 -PGJ 3 and derivatives thereof. In some aspects, the present derivatives of Δ 12 -PGJ 3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.

    专利号:US-8268936-B2
    优先权日:2005-01-04
    标题:Synthesis of hybrid block copolymers and uses thereof
    发明人:BREITENKAMP KURT; SILL KEVIN N
    权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
    摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.

    专利号:US-2012196989-A1
    优先权日:2005-02-11
    标题:Synthesis of homopolymers and block copolymers
    发明人:BREITENKAMP KURT; SILL KEVIN N
    权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC
    摘要:The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.

    专利号:US-8946456-B2
    优先权日:2010-06-10
    标 题 :Process for the preparation of 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol and (R)-feso-deacyl
    发明人:CIAMBECCHINI UMBERTO; TURCHETTA STEFANO; DE FERRA LORENZO; ZENONI MAURIZIO
    权利人:CIAMBECCHINI UMBERTO; TURCHETTA STEFANO; DE FERRA LORENZO; ZENONI MAURIZIO; CHEMI SPA
    摘要:The present invention regards an improved and industrially advantageous process for the preparation of the 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol intermediates, also called “feso chromenylâ€? and (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol, also called “(R)-feso deacylâ€?, which are in turn used in the synthesis of fesoterodine and in particular of fesoterodine fumarate. This process utilises reagents which are non-toxic and manageable at industrial level and enables obtaining a new stable and non-hygroscopic crystalline form of the key intermediate “(R)-feso deacylâ€?, called form B.

    专利号:US-4797427-A
    优先权日:1987-04-25
    标题:Aromatic diamines containing sulfonic acid aryl esters, a process for their production and their use in the production of polyurethane plastics
    发明人:SANDERS JOSEF; REIFF HELMUT; BALLE GERHARD; DIETERICH DIETER
    权利人:BAYER AG
    摘要:The present invention is directed to new aromatic diamines containing sulfonic acid aryl esters corresponding to the formula wherein R1 represents hydrogen, an optionally branched C1-C6 alkyl radical (preferably a methyl group), a C1-C6 alkoxy radical or a halogen atom (preferably chlorine) and R2 and R3 which may be the same or different, represent hydrogen, an optionally branched C1-C20 (preferably C1-C6) alkyl radical, a C1-C6 alkoxy radical or a halogen atom (preferably chlorine). The present invention is also directed to a process for the production of the above aromatic diamines containing sulfonic acid esters by the reaction of optionally substituted sulfochlorides with optionally substituted phenols followed by hydrogenation. Finally, the present invention is directed to the use of aromatic diamines containing sulfonic acid aryl esters as a synthesis component for the production of polyurethane plastics by the isocyanate polyaddition process.

    专利号:EP-3049072-A1
    优先权日:2013-09-25
    标 题:Synthesis of delta 12-pgj3 and related compounds

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    合成参考文献


    摘要:Ewing, T. A.; Fraaije, M. W.; van Berkel, W. J. H., Science of Synthesis: Biocatalysis in Organic Synthesis, (2015) 3, 165.
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