📜对甲酚置于5%-Palladium/activated Carbon,Potassium Acetate,Sodium Hydroxide体系中,用 水 作为反应溶剂,化学反应 12.33H,反应生成 4-甲氧甲基苯酚 参考文献:Practical Process For The Air Oxidation Of Cresols: Part A. Mechanistic Investigations 标题:Practical Process For The Air Oxidation Of Cresols: Part A. Mechanistic Investigations 摘要:The Catalytic Air Oxidation Of P-Cresol And 2,6-Di-Tert-Butyl-4-Methylphenol To The Corresponding Benzaldehydes Was Investigated To Determine The Mechanism At Work In These Oxidation Reactions. A Number Of Intermediates And Byproducts,Mainly In The Form Of Dimers,Were Observed During The Course Of The Reactions,And Their Structures Were Elucidated By Spectroscopic And Chromatographic Methods. The Existence Of These Compounds In The Reaction Mixtures,And Their Proposed Methods Of Formation,Provided Further Insight Into The Mechanism Involved In These Oxidations. DOI:10.1021/op049845B
专利号:US-2016318862-A1 优先权日:2013-09-25 标 题:Synthesis of delta 12-pgj3 and related compounds 发明人:NICOLAOU KYRIACOS C; HERETSCH PHILIPP; HALE CHRISTOPHER R H; EL GHZAOUI ABDELLATIF EL MARROUNI; PULUKURI KIRAN KUMAR; YU RUOCHENG; GROVE CHARLES 权利人:UNIV RICE WILLIAM M 摘要:In one aspect, the present invention provides novel derivatives of Δ 12 -PGJ 3 and modular synthetic pathways to obtaining Δ 12 -PGJ 3 and derivatives thereof. In some aspects, the present derivatives of Δ 12 -PGJ 3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.
专利号:US-8268936-B2 优先权日:2005-01-04 标题:Synthesis of hybrid block copolymers and uses thereof 发明人:BREITENKAMP KURT; SILL KEVIN N 权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC 摘要:The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
专利号:US-2012196989-A1 优先权日:2005-02-11 标题:Synthesis of homopolymers and block copolymers 发明人:BREITENKAMP KURT; SILL KEVIN N 权利人:BREITENKAMP KURT; SILL KEVIN N; INTEZYNE TECHNOLOGIES INC 摘要:The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same.
专利号:US-8946456-B2 优先权日:2010-06-10 标 题 :Process for the preparation of 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol and (R)-feso-deacyl 发明人:CIAMBECCHINI UMBERTO; TURCHETTA STEFANO; DE FERRA LORENZO; ZENONI MAURIZIO 权利人:CIAMBECCHINI UMBERTO; TURCHETTA STEFANO; DE FERRA LORENZO; ZENONI MAURIZIO; CHEMI SPA 摘要:The present invention regards an improved and industrially advantageous process for the preparation of the 2-hydroxy-4-phenyl-3,4-dihydro-2H-chromen-6-yl-methanol intermediates, also called “feso chromenylâ€? and (R)-2-[3-(diisopropylamino)-1-phenylpropyl]-4-(hydroxymethyl)phenol, also called “(R)-feso deacylâ€?, which are in turn used in the synthesis of fesoterodine and in particular of fesoterodine fumarate. This process utilises reagents which are non-toxic and manageable at industrial level and enables obtaining a new stable and non-hygroscopic crystalline form of the key intermediate “(R)-feso deacylâ€?, called form B.
专利号:US-4797427-A 优先权日:1987-04-25 标题:Aromatic diamines containing sulfonic acid aryl esters, a process for their production and their use in the production of polyurethane plastics 发明人:SANDERS JOSEF; REIFF HELMUT; BALLE GERHARD; DIETERICH DIETER 权利人:BAYER AG 摘要:The present invention is directed to new aromatic diamines containing sulfonic acid aryl esters corresponding to the formula wherein R1 represents hydrogen, an optionally branched C1-C6 alkyl radical (preferably a methyl group), a C1-C6 alkoxy radical or a halogen atom (preferably chlorine) and R2 and R3 which may be the same or different, represent hydrogen, an optionally branched C1-C20 (preferably C1-C6) alkyl radical, a C1-C6 alkoxy radical or a halogen atom (preferably chlorine). The present invention is also directed to a process for the production of the above aromatic diamines containing sulfonic acid esters by the reaction of optionally substituted sulfochlorides with optionally substituted phenols followed by hydrogenation. Finally, the present invention is directed to the use of aromatic diamines containing sulfonic acid aryl esters as a synthesis component for the production of polyurethane plastics by the isocyanate polyaddition process.
专利号:EP-3049072-A1 优先权日:2013-09-25 标 题:Synthesis of delta 12-pgj3 and related compounds