CAS: 401-79-6; 1-Methyl-3-(Trifluoromethyl)Benzene

上下游产品

CAS号705-29-3 3-三氟甲基氯苄 | CAS号401-78-5 间溴三氟甲苯 | CAS号676-58-4 甲基氯化镁 | CAS号115571-61-4 2,4-二氯-5-甲基三氟甲苯 | CAS号349-75-7 3-(三氟甲基)苄醇 | CAS号109-06-8 2-甲基吡啶 | CAS号75-63-8 三氟溴甲烷 | CAS号81290-20-2 (三氟甲基)三甲基硅烷 | CAS号108-88-3 甲苯 | CAS号591-17-3 3-溴甲苯 | CAS号349-75-7 3-(三氟甲基)苄醇 | CAS号92891-23-1 3-甲基-2-硝基三氟甲苯 | CAS号67192-42-1 3-甲基-4-硝基三氟甲苯 | CAS号87617-21-8 5-甲基-2-硝基三氟甲苯 | CAS号96783-80-1 1-甲基-3-硝基-5-(三氟甲基)苯 | CAS号402-23-3 3-(三氟甲基)苯甲酰溴 | CAS号67169-22-6 2-甲基-4-三氟甲基苯胺 | CAS号87617-23-0 2-氨基-5-甲基三氟甲苯 | CAS号96100-12-8 3-氨基-5-甲基三氟甲苯 | CAS号88301-98-8 2-甲基-6-三氟甲基苯胺

间二三氟甲苯置于二甲基苯基硅烷体系中,用 氘代苯 作为反应溶剂,化学反应 135.0H,反应生成 3-甲基三氟甲苯
参考文献:使用双 (Nhc) 镍 (0) 配合物裂解三氟甲基芳烃中的 C(Sp3)-f 键
标题:使用双 (Nhc) 镍 (0) 配合物裂解三氟甲基芳烃中的 C(Sp3)-f 键
摘要:描述了将三氟甲基芳烃中的 C(Sp3)-F 键氧化加成到镍 (0) 配合物的第一个例子.带有两个低空间位阻要求的 N-杂环卡宾 (Nhc) 配体的镍 (0) 配合物能够裂解三氟甲基芳烃的 C(Sp3)-F 键,得到相应的反式二氟苄基镍 (II) 氟化物配合物.分离和表征研究表明,C(Sp3)-F 键的裂解是通过 η2-芳烃镍 (0) 配合物进行的.利用这些氟化镍 (II) 配合物的反应性,我们开发了一种使用氢硅烷对三氟甲基芳烃进行催化加氢脱氟的方法.一项计算研究表明,由两个相对较小的 Nhc 配体支持的富电子镍 (0) 中心通过 Syn-Sn2' 机制裂解 C(Sp3)-F 键.
DOI:10.1021/jacs.0C09639

专利信息

专利号:WO-0140193-A1
优先权日:1999-12-03
标题:Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
权利人:CHEMRX ADVANCED TECHNOLOGIES I; BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula (I). Also claimed are novel intermediates and their methods of synthesis.

专利号:US-2002103381-A1
优先权日:2000-11-30
标 题 :Method for the synthesis of pyrazolines
发明人：BOLDI ARMEN M
摘要:The present invention provides a method for the synthesis of compounds of Formula I: n n n Also claimed are novel intermediates and their methods of synthesis.

专利号:US-6255545-B1
优先权日:1999-06-11
标 题 :Process for the synthesis of 3,5-bis(trifluoromethyl)-bromobenzene
发明人：CVETOVICH RAYMOND; TSAY FUH-RONG
权利人:MERCK & CO INC
摘要:The present invention is concerned with a novel process for the preparation of 3,5-bis(trifluoromethyl)bromobenzene (CAS 328-70-1). This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:US-4049710-A
优先权日:1976-02-24
标题:Novel carbamimidoyl chlorides and their use in the synthesis of herbicidal triazinediones
发明人：TOCKER STANLEY
权利人:DU PONT
摘要:Carbamimidoyl chlorides of the formula: WHERE R2 is alkyl of 1-4 carbon atoms are useful as intermediates in the synthesis of herbicidal triazinediones of the formula: where R1 is certain organic radicals.

专利号:US-6469164-B2
优先权日:2000-06-08
标题:Process for the synthesis of (2R, 2-alpha-R)-4-benzyl-2-[1-(3,5-bis (trifluoromethyl)phenyl)ethoxy]-1,4-oxazine-3-one
发明人：BRANDS KAREL M JOS; PAYACK JOSEPH F; PYE PHILIP J
权利人:MERCK & CO INC
摘要:The present invention is concerned with novel processes for the preparation of (2R, 2-alpha-R)-4-benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy-1,4-oxazin-3-one. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.

专利号:US-6777580-B2
优先权日:1999-07-01
标题:Process for the synthesis of (R)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol by asymmetric transfer hydrogenation
发明人：DEVINE PAUL; KARL HANSEN
权利人:MERCK & CO INC
摘要:The present invention is concerned with novel processes for the preparation of (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-ol. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.